ChemicalBook > CAS DataBase List > 5-(3,5-difluorobenzyl)-1H-indazol-3-amine

5-(3,5-difluorobenzyl)-1H-indazol-3-amine

Product Name
5-(3,5-difluorobenzyl)-1H-indazol-3-amine
CAS No.
1108745-30-7
Chemical Name
5-(3,5-difluorobenzyl)-1H-indazol-3-amine
Synonyms
(3,5-difluorobenzyl)-1H-indazol-3-amine;5-(3,5-difluorobenzyl)-1H-indazol-3-amine;5-(3,5- difluorobenzyl)-1 h- azole-3-amine;3-Amino-5-(3,5-difluorobenzyl)-1H-indazole;5-(3,5-difluoro-benzyl)-1H-indazol-3-ylamine;5-[(3,5-Difluorophenyl)methyl]-1H-indazol-3-amine;1H-Indazol-3-amine, 5-[(3,5-difluorophenyl)methyl]-;5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-amine - [D81383]
CBNumber
CB62756082
Molecular Formula
C14H11F2N3
Formula Weight
259.25
MOL File
1108745-30-7.mol
More
Less

5-(3,5-difluorobenzyl)-1H-indazol-3-amine Property

Boiling point:
450.7±40.0 °C(Predicted)
Density 
1.399±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
pka
14.82±0.40(Predicted)
Appearance
White to off-white Solid
InChI
InChI=1S/C14H11F2N3/c15-10-4-9(5-11(16)7-10)3-8-1-2-13-12(6-8)14(17)19-18-13/h1-2,4-7H,3H2,(H3,17,18,19)
InChIKey
CZQCRNRCCQSJHD-UHFFFAOYSA-N
SMILES
N1C2=C(C=C(CC3=CC(F)=CC(F)=C3)C=C2)C(N)=N1
More
Less

Safety

HS Code 
2933998090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

AK Scientific
Product number
2407DF
Product name
5-(3,5-Difluorobenzyl)-1H-indazol-3-amine
Packaging
1g
Price
$224
Updated
2021/12/16
Apolloscientific
Product number
PC52452
Product name
5-[(3,5-Difluorophenyl)methyl]-1H-indazol-3-amine
Packaging
250mg
Price
$395
Updated
2021/12/16
SynQuest Laboratories
Product number
3H30-3-AE
Product name
5-[(3,5-Difluorophenyl)methyl]-1H-indazol-3-amine
Packaging
250mg
Price
$632
Updated
2021/12/16
Chemenu
Product number
CM119287
Product name
3-Amino-5-(3,5-difluorobenzyl)-1H-indazole
Purity
99%
Packaging
1000g
Price
$6072
Updated
2021/12/16
Ambeed
Product number
A633080
Product name
3-Amino-5-(3,5-difluorobenzyl)-1H-indazole
Purity
95%
Packaging
10g
Price
$344
Updated
2021/12/16
More
Less

5-(3,5-difluorobenzyl)-1H-indazol-3-amine Chemical Properties,Usage,Production

Uses

5-(3,5-difluorobenzyl)-1H-indazol-3-amine is an intermediates of Entrectinib(RXDX-101). Entrectinib (RXDX-101, NMS-E628) is an orally bioavailable pan-TrkA/B/C, ROS1 and ALK inhibitor with IC50 ranging between 0.1 and 1.7 nM. Entrectinib (RXDX-101) induces autophagy.

5-(3,5-difluorobenzyl)-1H-indazol-3-amine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5-(3,5-difluorobenzyl)-1H-indazol-3-amine Suppliers

Suzhou Crst Pharmatech Co., Ltd.
Tel
0512-62910395 17751098781
Fax
0512-62910396
Email
sales@crstpharma.com
Country
China
ProdList
499
Advantage
58
Jinan Guoding Pharmaceutical Technology Co., Ltd.
Tel
053167801621 15665775653
Fax
053167801621
Email
sales@guodingpharma.com
Country
China
ProdList
491
Advantage
58
Shandong Xuanshuo Pharmaceutical Technology Co. LTD
Tel
15269103900
Email
suchangzhou@shiningpharm.com
Country
China
ProdList
330
Advantage
58
Shanghai Biobond Pharmaceutical Co.,Ltd.
Tel
21-68719686 18917373795
Fax
021-68719686
Email
sales@sh-biobond.cn
Country
China
ProdList
83
Advantage
58
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
Tel
17702719238 18971495150;
Email
sales@sun-shinechem.com
Country
China
ProdList
1077
Advantage
64
Shanghai Hope Chem Co., Ltd.,
Tel
+21-18501659228 18501659228
Fax
sales@hope-chem.com
Email
info@hope-chem.com
Country
China
ProdList
474
Advantage
55
Anhui Dexinjia Biopharm Co., Ltd
Tel
0531-82375892 15553111391
Email
3276840968@qq.com
Country
China
ProdList
301
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Nanjing Chalf-Pharm Technology Co., Ltd.
Tel
025-57018978 18251899859
Fax
025-57018008
Email
sales@chalf-pharm.com
Country
China
ProdList
5674
Advantage
50
More
Less

View Lastest Price from 5-(3,5-difluorobenzyl)-1H-indazol-3-amine manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
5-(3,5-difluorobenzyl)-1H-indazol-3-amine 1108745-30-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-30
Anhui Dexinjia Biopharm Co., Ltd
Product
5-(3,5-difluorobenzyl)-1H-indazol-3-amine 1108745-30-7
Price
US $15.00-50.00/kg
Min. Order
1kg
Purity
NLT98%
Supply Ability
5 ton per month
Release date
2023-04-02
Zibo Hangyu Biotechnology Development Co., Ltd
Product
5-(3,5-difluorobenzyl)-1H-indazol-3-amine 1108745-30-7
Price
US $90.00-900.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-10-27

1108745-30-7, 5-(3,5-difluorobenzyl)-1H-indazol-3-amineRelated Search:


  • 5-(3,5-difluorobenzyl)-1H-indazol-3-amine
  • 3-Amino-5-(3,5-difluorobenzyl)-1H-indazole
  • 5-(3,5-difluoro-benzyl)-1H-indazol-3-ylamine
  • 5-[(3,5-Difluorophenyl)methyl]-1H-indazol-3-amine
  • 1H-Indazol-3-amine, 5-[(3,5-difluorophenyl)methyl]-
  • 5-(3,5- difluorobenzyl)-1 h- azole-3-amine
  • (3,5-difluorobenzyl)-1H-indazol-3-amine
  • 5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-amine - [D81383]
  • 1108745-30-7