ChemicalBook > CAS DataBase List > 5-(3,5-difluorobenzyl)-1H-indazol-3-amine
5-(3,5-difluorobenzyl)-1H-indazol-3-amine
- Product Name
- 5-(3,5-difluorobenzyl)-1H-indazol-3-amine
- CAS No.
- 1108745-30-7
- Chemical Name
- 5-(3,5-difluorobenzyl)-1H-indazol-3-amine
- Synonyms
- (3,5-difluorobenzyl)-1H-indazol-3-amine;5-(3,5-difluorobenzyl)-1H-indazol-3-amine;5-(3,5- difluorobenzyl)-1 h- azole-3-amine;3-Amino-5-(3,5-difluorobenzyl)-1H-indazole;5-(3,5-difluoro-benzyl)-1H-indazol-3-ylamine;5-[(3,5-Difluorophenyl)methyl]-1H-indazol-3-amine;1H-Indazol-3-amine, 5-[(3,5-difluorophenyl)methyl]-;5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-amine - [D81383]
- CBNumber
- CB62756082
- Molecular Formula
- C14H11F2N3
- Formula Weight
- 259.25
- MOL File
- 1108745-30-7.mol
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5-(3,5-difluorobenzyl)-1H-indazol-3-amine Property
- Boiling point:
- 450.7±40.0 °C(Predicted)
- Density
- 1.399±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 14.82±0.40(Predicted)
- Appearance
- White to off-white Solid
- InChI
- InChI=1S/C14H11F2N3/c15-10-4-9(5-11(16)7-10)3-8-1-2-13-12(6-8)14(17)19-18-13/h1-2,4-7H,3H2,(H3,17,18,19)
- InChIKey
- CZQCRNRCCQSJHD-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=C(CC3=CC(F)=CC(F)=C3)C=C2)C(N)=N1
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Safety
- HS Code
- 2933998090
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
AK Scientific
- Product number
- 2407DF
- Product name
- 5-(3,5-Difluorobenzyl)-1H-indazol-3-amine
- Packaging
- 1g
- Price
- $224
- Updated
- 2021/12/16
Apolloscientific
- Product number
- PC52452
- Product name
- 5-[(3,5-Difluorophenyl)methyl]-1H-indazol-3-amine
- Packaging
- 250mg
- Price
- $395
- Updated
- 2021/12/16
SynQuest Laboratories
- Product number
- 3H30-3-AE
- Product name
- 5-[(3,5-Difluorophenyl)methyl]-1H-indazol-3-amine
- Packaging
- 250mg
- Price
- $632
- Updated
- 2021/12/16
Chemenu
- Product number
- CM119287
- Product name
- 3-Amino-5-(3,5-difluorobenzyl)-1H-indazole
- Purity
- 99%
- Packaging
- 1000g
- Price
- $6072
- Updated
- 2021/12/16
Ambeed
- Product number
- A633080
- Product name
- 3-Amino-5-(3,5-difluorobenzyl)-1H-indazole
- Purity
- 95%
- Packaging
- 10g
- Price
- $344
- Updated
- 2021/12/16
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5-(3,5-difluorobenzyl)-1H-indazol-3-amine Chemical Properties,Usage,Production
Uses
5-(3,5-difluorobenzyl)-1H-indazol-3-amine is an intermediates of Entrectinib(RXDX-101). Entrectinib (RXDX-101, NMS-E628) is an orally bioavailable pan-TrkA/B/C, ROS1 and ALK inhibitor with IC50 ranging between 0.1 and 1.7 nM. Entrectinib (RXDX-101) induces autophagy.
5-(3,5-difluorobenzyl)-1H-indazol-3-amine Preparation Products And Raw materials
Raw materials
Preparation Products
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5-(3,5-difluorobenzyl)-1H-indazol-3-amine Suppliers
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View Lastest Price from 5-(3,5-difluorobenzyl)-1H-indazol-3-amine manufacturers
Henan Aochuang Chemical Co.,Ltd.
- Product
- 5-(3,5-difluorobenzyl)-1H-indazol-3-amine 1108745-30-7
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-30
Anhui Dexinjia Biopharm Co., Ltd
- Product
- 5-(3,5-difluorobenzyl)-1H-indazol-3-amine 1108745-30-7
- Price
- US $15.00-50.00/kg
- Min. Order
- 1kg
- Purity
- NLT98%
- Supply Ability
- 5 ton per month
- Release date
- 2023-04-02
Zibo Hangyu Biotechnology Development Co., Ltd
- Product
- 5-(3,5-difluorobenzyl)-1H-indazol-3-amine 1108745-30-7
- Price
- US $90.00-900.00/kg
- Min. Order
- 10kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-10-27