Ceftezole
- Product Name
- Ceftezole
- CAS No.
- 26973-24-0
- Chemical Name
- Ceftezole
- Synonyms
- CTZ;CG-B 3Q;FR 10123;Celoslin;ceftezol;CEFTEZOLE;CEPHTEZOL;Ceftazole;NSC 102805;Ceftezole Acid
- CBNumber
- CB6277787
- Molecular Formula
- C13H12N8O4S3
- Formula Weight
- 440.48
- MOL File
- 26973-24-0.mol
Ceftezole Property
- Melting point:
- 155°C (dec.)
- Density
- 2.09
- storage temp.
- Store at -20°C
- solubility
- DMSO: 88 mg/mL (199.78 mM);;
- pka
- 2.60±0.50(Predicted)
- λmax
- 273nm(Phosphate buffer sol.)(lit.)
- Merck
- 14,1948
- CAS DataBase Reference
- 26973-24-0(CAS DataBase Reference)
Safety
- Hazard Codes
- T+,N
- Risk Statements
- 21/22-26-50/53
- Safety Statements
- 28-36/37-45-61
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
N-Bromosuccinimide Price
- Product number
- 716707
- Product name
- Cadmium zinc telluride
- Purity
- 99.9999% trace metals basis
- Packaging
- 5g
- Price
- $146
- Updated
- 2023/01/07
- Product number
- C244315
- Product name
- Ceftezole
- Packaging
- 10g
- Price
- $85
- Updated
- 2021/12/16
- Product number
- FC41103
- Product name
- Ceftezole
- Packaging
- 5G
- Price
- $90
- Updated
- 2021/12/16
- Product number
- FC41103
- Product name
- Ceftezole
- Packaging
- 10g
- Price
- $144
- Updated
- 2021/12/16
- Product number
- J11705
- Product name
- Ceftezole
- Packaging
- 25mg
- Price
- $38
- Updated
- 2021/12/16
Ceftezole Chemical Properties,Usage,Production
Originator
Ceftezole,Arocor Holdings Inc.
Uses
Ceftezole is a β-lactam, cephem antibiotic. It also exhibits potent α-glucosidase inhibitory activity and antidiabetic effect in streptozotocin-induced mouse.
Uses
A direct bandgap semiconductor, it is used in a variety of applications, including radiation detectors, photorefractive gratings, electro-optic modulators, solar cells, and terahertz generation and detection. The band gap varies from approximately 1.4 to 2.2 eV, depending on composition.
Definition
ChEBI: Ceftezole is a first-generation cephalosporin antibiotic having (1,3,4-thiadiazol-2-ylsulfanyl)methyl and [2-(1H-tetrazol-1-yl)acetamido side groups located at positions 3 and 7 respectively. It is a cephalosporin and a member of thiadiazoles.
Manufacturing Process
To a solution of 1 equivalent (eq.) of 1H-tetrazole-1-acetic acid and 1 eq. of
triethylamine in 20 ml of tetrahydrofuran cooled to -20°C was added 1 eq. of
pivaloyl chloride. After thirty-minute stirring of the mixture 20 ml of a
chloroform solution containing 1 eq. of and 1 eq. of triethylamine was poured
into the solution cooled at -10°C during a period of 30 minutes. The resulting
mixed solution was stirred for 30 minutes at the same temperature, for 1 hour
in an ice-water mixture and for 3 hours at room temperature. Removal of a
solvent from the reaction mixture afforded an oily residue, which was
dissolved into 15 ml of 10% sodium bicarbonate aqueous solution. The
resulting aqueous layer was adjusted to pH 1.0-2.0 with 10% hydrochloric
acid, washed with ether and extracted with ethyl acetate. The extract was
washed with water, dried over sodium sulfate and concentrated under reduced
pressure leaving a residue which was triturated with ethyl acetate to obtain 3-
acetoxymethyl-8-oxo-7-(2-tetrazol-1-acetylamino)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid.
A solution of 1 eq. of sodium salt of 3-acetoxymethyl-8-oxo-7-(2-tetrazol-1-
acetylamino)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid (it may be
prepared with equivalent of sodium bicarbonate and above named acid) and 1
eq. of [1.3.4]-thiadiazole-2-thiol in 20 ml of phosphate buffer (pH 6.4) was
stirred for 5.5 hours at 60°C. The reaction mixture was adjusted to pH 2.0
with 5% hydrochloric acid and treated with ethyl acetate to form a title
compound - ceftezole.
Therapeutic Function
Antibiotic
General Description
Cadmium zinc telluride (Cd1-xZnxTe or CZT) can detect nuclear radiation hence, CZT with Zn concentrations between 0.1-0.2 may be used in the making of radiation detectors of X-ray and gamma-ray spectrometers.
Ceftezole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Ceftezole manufacturers
- Product
- Ceftezole 26973-24-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
- Product
- Ceftezole 26973-24-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- Ceftezole 26973-24-0
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1KG
- Purity
- 99.0%+
- Supply Ability
- 300 MT
- Release date
- 2020-05-23