Overview Reference
ChemicalBook > CAS DataBase List > 2,6-DI-TERT-BUTYLPYRIDINE

2,6-DI-TERT-BUTYLPYRIDINE

Overview Reference
Product Name
2,6-DI-TERT-BUTYLPYRIDINE
CAS No.
585-48-8
Chemical Name
2,6-DI-TERT-BUTYLPYRIDINE
Synonyms
2,6-DI-T-BUTYLPYRIDINE;2,6-Bis(tert-butyl)pyridine;NSC 175805;2,6-DI-TERT-BUTYLPYRIDINE;Pyridine, 2,6-di-tert-butyl-;2,6-Di-tert-butylpyridine>2,6-DI-TERT-BUTYLPYRIDINE 97%;2,6-Di-tert-butylpyridine ,96%;2,6-DI-TERT-BUTYLPYRIDINE, >=97%;2,6-Di-tert-butylpyridine
CBNumber
CB6293437
Molecular Formula
C13H21N
Formula Weight
191.31
MOL File
585-48-8.mol
More
Less

2,6-DI-TERT-BUTYLPYRIDINE Property

Melting point:
2°C(lit.)
Boiling point:
100-101 °C/23 mmHg (lit.)
Density 
0.852 g/mL at 25 °C (lit.)
refractive index 
1.472-1.474
Flash point:
72 °C
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Liquid
pka
3.58(at 25℃)
Specific Gravity
0.852
color 
Clear yellow
Water Solubility 
Miscible with alcohol, acetone, and hexane. Immiscible with water.
Merck 
14,3036
BRN 
125886
Dielectric constant
3.3900000000000001
Stability:
Stable. Combustible. Incompatible with strong acids, strong oxidizing agents.
InChIKey
UWKQJZCTQGMHKD-UHFFFAOYSA-N
CAS DataBase Reference
585-48-8(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xn,Xi
Risk Statements 
36/37/38-22
Safety Statements 
37/39-26-36/37/39-36
RIDADR 
3267
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29339900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
219584
Product name
2,6-Di-tert-butylpyridine
Purity
≥97%
Packaging
1g
Price
$54.6
Updated
2024/03/01
Sigma-Aldrich
Product number
219584
Product name
2,6-Di-tert-butylpyridine
Purity
≥97%
Packaging
5g
Price
$193
Updated
2024/03/01
TCI Chemical
Product number
D1804
Product name
2,6-Di-tert-butylpyridine
Purity
>97.0%(GC)
Packaging
5g
Price
$142
Updated
2024/03/01
TCI Chemical
Product number
D1804
Product name
2,6-Di-tert-butylpyridine
Purity
>97.0%(GC)
Packaging
25g
Price
$489
Updated
2024/03/01
Alfa Aesar
Product number
H55761
Product name
2,6-Di-tert-butylpyridine, 97+%
Packaging
1g
Price
$42.65
Updated
2024/03/01
More
Less

2,6-DI-TERT-BUTYLPYRIDINE Chemical Properties,Usage,Production

Overview

2,6-Di-tert-butylpyridine is a weak base used in the preparation of 2, 6-di-tert-butylpyridine hydrotriflate. It is used as a proton scavenger to check the progress of the living polymerization of isobutylene. It is associated with cerric ammonium nitrate and used in the alfa-enolation of aldehydes. It is involved in the preparation of vinyl triflate using polymer-bound 2,6-di-tert-butylpyridine. Since it was first synthesized by Brown and Kanner[1], 2,6-di-tert-butylpyridine has attracted the interest of many researchers because of its unusually low basicity: with its two-alkyl substituents, DTBP is nevertheless a weaker base than unsubstituted pyridine in aqueous solution. Brown and Kanner[1] and others[2] proposed that the abnormally low basicity of DTBP was caused by steric hindrance to hydration of DTBPH+. Recent determinations of gas-phase proton affinities of DTBP and other alkyl-substituted pyridines showed that the basicity of DTBP in the gas phase was normal[2, 3], which confirmed that its weak basicity in water was due to solvent effects on DTBP and (or) DTBPH+. A complete analysis of the thermodynamic cycles linking the protonation processes of DTBP and other pyridines in the gas phase and in aqueous solution led Arnett and Chawla[2] to conclude that there was indeed some hindrance to the hydration of DTBPH+ as reflected in its abnormally low enthalpy of hydration. However, more recently Hopkins et al.[3], after investigating the protonation of additional tertbutylpyridines and repeating the thermodynamic determinations of Amett and Chawla[2] of DTBP, concluded from their new data that the hydration enthalpy of DTBPH+ was normal but that the corresponding entropy was abnormal; they suggested that the rotation of the water molecule attached to DTBPH+ and of -CMe3 was restricted. These results and conclusions were in agreement with the gas phase studies of Moet-Ner and Sieck[4] on the attachment of one water molecule to a series of pyridinium cations including DTBPH+.

Reference

  1. H. C. BROWN and B. KANNERJ. Am. Chem. Soc. 75, 3865 (1953).
  2. E. M. ARNETT and B. CHAWLAJ. Am. Chem. Soc. 101, 7141 (1979).
  3. H.P.HOPKINSD,.V.JAHAGIRDAP.RS,.MOULIKD,.H.AUE, H. M. WEBB,W. R. DAVIDSON and M. D. PEDLEY. J.. Am. Chem. Soc. 106,4341 (1984).
  4. M. MEOT-NEaRnd L. W. SIECK J. Am. Chem. Soc. 105, 2956 (1983) 

Chemical Properties

dark brown liquid

Uses

2,6-Di-tert-butylpyridine is used in the preparation of 2, 6-di-tert-butylpyridine hydrotriflate. It is used as a proton scavenger to check the progress of the living polymerization of isobutylene. It is associated with cerric ammonium nitrate and used in the alfa-enolation of aldehydes. It is involved in the preparation of vinyl triflate using polymer-bound 2,6-di-tert-butylpyridine.

Uses

2,6-Di-tert-butylpyridine was used as proton trapping agent to investigate the living polymerization of isobutylene. It was also used with cerric ammonium nitrate in the α-enolation of aldehydes leading to 1,4-dicarbonyl systems.

Definition

ChEBI: 2,6-di-tert-butylpyridine is a member of pyridines.

General Description

Reactivity of 2,6-di-tert-butylpyridine with iron(III) tetraphenylporphyrin pi-cation radical has been examined by proton NMR spectroscopy. Reaction of 2,6-di-tert-butylpyridine with methyl iodide and methyl fluorosulfonate under high pressure has been reported.

Purification Methods

Redistil it from KOH pellets. [Beilstein 20 III/IV 2868.]

2,6-DI-TERT-BUTYLPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2,6-DI-TERT-BUTYLPYRIDINE Suppliers

Americas 1 Australia 1 Belgium 2 China 175 Europe 1 France 1 Germany 3 India 5 Japan 2 Lithuania 1 Switzerland 1 The Netherlands 1 United Kingdom 10 United States 21 Global 225
ITIC MEDCHEM(SUZHOU) CO.,LTD.
Tel
0512-68323967 18015559028
Fax
+86-512-69200360
Email
sales@iticmedchem.com
Country
China
ProdList
411
Advantage
61
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40240
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7639
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44700
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9550
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Shanghai Harvest Chemical Industrial Co., Ltd.
Tel
21-31038972 15721252604
Fax
+86-21-51385350
Email
ammyzuo@harvest-chem.com
Country
China
ProdList
2511
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
18089
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-021-64543801 13764082696
Email
2355241799@qq.com
Country
China
ProdList
42982
Advantage
64
Suzhou Ryan Pharmaceutical Technology Co., Ltd.
Tel
0512-68780025,68780026 18962125825
Email
sales@ryanchem.com
Country
China
ProdList
161
Advantage
62
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
Shanghai Shenyue Chemical Co., Ltd.
Tel
021-021-52212593 15300879511
Fax
+86 (21) 51062076
Email
sales@nuohey.com
Country
China
ProdList
5102
Advantage
60
Suzhou Guide Fine Material Co.Ltd.
Tel
136-16210669 13914021065
Fax
0512-66627360
Email
sales@guide-chemicals.com
Country
China
ProdList
294
Advantage
60
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6139
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22519
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25014
Advantage
65
Yancheng Orgunion Pharmaceutical Sci & Tech Co., Ltd.
Tel
0515-89701588 13770166955
Fax
0515-87400189
Email
orgunion@orgunion.com
Country
China
ProdList
620
Advantage
55
Aloespharm Co., Ltd.
Tel
021-20960837
Fax
021-20960837
Email
market@aloespharm.com
Country
China
ProdList
1303
Advantage
55
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9352
Advantage
58
Mashilabs (Shanghai) Co.,Ltd.
Tel
19916721580
Fax
QQ：3154870176
Email
info@mashilabs.com
Country
China
ProdList
4115
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15878
Advantage
55
SHANGHAI BANGCHENG CHEMICAL Co.,Ltd.
Tel
021-69106960 13701823733
Fax
021-69106780
Email
13701823733@163.com
Country
China
ProdList
4775
Advantage
60
Shanghai Yongye Biotechnology Co., Ltd.
Tel
86-021-61559134 15921386130
Fax
021-55068248
Email
3423497944@qq.com
Country
China
ProdList
8147
Advantage
55
Beijing Xinsavi Chemical Technology Co., Ltd.
Tel
010-56218822 13717722232
Fax
010-56218800
Email
xinsavichem@163.com
Country
China
ProdList
3201
Advantage
56
Beijing Holiyang Chemical Co. Ltd.
Tel
13718199399
Fax
QQ : 206661479
Email
holiyangchem@163.com
Country
China
ProdList
3387
Advantage
56
Shanghai YouPeng Chemical Co. Ltd.
Tel
021-69005955 13701776567
Fax
021-69005775
Email
youpengchem@163.com
Country
China
ProdList
4303
Advantage
56
Sichuan Hainuowei Technology Co. Ltd.
Tel
13708085536
Fax
QQ : 121102042
Email
hanovichem@163.com
Country
China
ProdList
3389
Advantage
56
Shanghai Kaisai Chemical Co., Ltd
Tel
021-33516722 13701817765
Fax
021-33516776
Email
kaisaichem@163.com
Country
China
ProdList
4751
Advantage
58
Beijing HuaYangZhicheng Technology Co., Ltd.
Tel
13716033033
Fax
010-56276266
Email
hanchochem@163.com
Country
China
ProdList
2960
Advantage
50
Shanghai LanRun Chemical Co., Ltd.
Tel
021-69515658 ; 69515628 13701998368
Fax
021-69515998
Email
longrunchem@163.com
Country
China
ProdList
3920
Advantage
50
Shanghai Rolead Chemical Technology Co., Ltd.
Tel
021-69992220 13701886816
Fax
021-69992237
Email
roleadchem@163.com
Country
China
ProdList
4759
Advantage
50
Shanghai Kangtuo Chemical Co., Ltd.
Tel
021-69185552 13701777608
Fax
021-69186006
Email
kangtuochem@163.com
Country
China
ProdList
4370
Advantage
55
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12357
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Shanghai Uchem Inc.
Tel
15618758386 15618758386
Fax
QQ:3004479444
Email
sales3@myuchem.com
Country
China
ProdList
2013
Advantage
55
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
2853979813@qq.com
Country
China
ProdList
7990
Advantage
55
Chengdu JingXin Technology Co., Ltd.
Tel
028-85005297 13980656781
Fax
028-85005529
Email
jingxin73730@163.com
Country
China
ProdList
3280
Advantage
50
Chemspon Bio-Tech Co., Ltd
Tel
0571-88937695 88937835 13606537248
Fax
0571-88933015 QQ:1423821043
Email
sales@chemspon.com
Country
China
ProdList
240
Advantage
58
skychemical Co.Ltd
Tel
021-20960837,QQ1332204249
Fax
021-20960837
Email
sales@skychemical.com
Country
China
ProdList
3320
Advantage
55
Nanjing Vital Chemical Co., Ltd.
Tel
025-87193546 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
9030
Advantage
60
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862，442785678，326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9638
Advantage
58
More
Less

View Lastest Price from 2,6-DI-TERT-BUTYLPYRIDINE manufacturers

Suzhou Ryan Pharmachem Technology Co.,Ltd.
Product
2,6-DI-TERT-BUTYLPYRIDINE 585-48-8
Price
US $0.00-0.00/kg
Min. Order
10kg
Purity
98%
Supply Ability
hundred kgs grade
Release date
2023-05-08
Hebei Guanlang Biotechnology Co., Ltd.
Product
2,6-DI-TERT-BUTYLPYRIDINE 585-48-8
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2022-09-29
Dideu Industries Group Limited
Product
2,6-DI-TERT-BUTYLPYRIDINE 585-48-8
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-28

585-48-8, 2,6-DI-TERT-BUTYLPYRIDINERelated Search:

2,6-DI-TERT-BUTYLPYRIDINE, POLYMER-BOUND 2,4-Di-tert-butylpyridine 4-Methyl-2,6-di-tert-butylpyridine 2,6-DITERT-BUTYLISONICOTINAMIDE 2,6-DI-TERT-BUTYLISONICOTINIC ACID 2,6-DI-TERT-BUTYLPYRIDINE, POLYMER-BOUND 2,4,6-TRI-TERT-BUTYLPYRIDINE SPECS AC-907/25005251 2,6-DI-TERT-BUTYLPYRIDINE 2,6-DITERT-BUTYLISONICOTINONITRILE 4-(BROMOMETHYL)-2,6-DI-TERT-BUTYLPYRIDINE

  • Pyridine, 2,6-bis(1,1-dimethylethyl)-
  • Pyridine, 2,6-di-tert-butyl-
  • 2,6-DI-T-BUTYLPYRIDINE
  • 2,6-DI-TERT-BUTYLPYRIDINE
  • 2,6-Bis(1,1-dimethylethyl)pyridine
  • 2,6-Bis(tert-butyl)pyridine
  • 2,6-Di-tert-butylpyridine ,96%
  • 2,6-DI-TERT-BUTYLPYRIDINE 97%
  • 2,6-DI-TERT-BUTYLPYRIDINE, >=97%
  • 2,6-Di-tert-butylpyridine, 97% 25GR
  • 2,6-Di-tert-butylpyridine, 97% 5GR
  • NSC 175805
  • 2,6-Di-<i>tert</i>-butylpyridine
  • 2,6-Di-tert-butylpyridine, 96%, for synthesis
  • 2,6-Di-tert-butylpyridine&gt
  • 2,6-DI-TERT-BUTYLPYRIDINE ISO 9001：2015 REACH
  • CAS585-48-8 2,6-DI-TERT-BUTYLPYRIDINE
  • 585-48-8
  • C13H21N
  • Pyridines
  • Heterocyclic Building Blocks
  • Building Blocks
  • C9 to C46
  • Pyridines, Pyrimidines, Purines and Pteredines
  • Heterocyclic Compounds
  • C9 to C46
  • Heterocyclic Building Blocks
  • Pyridines