ChemicalBook > CAS DataBase List > 2,3-DIHYDRO-1,4-BENZODIOXIN-5-YLMETHANOL

2,3-DIHYDRO-1,4-BENZODIOXIN-5-YLMETHANOL

Product Name
2,3-DIHYDRO-1,4-BENZODIOXIN-5-YLMETHANOL
CAS No.
274910-19-9
Chemical Name
2,3-DIHYDRO-1,4-BENZODIOXIN-5-YLMETHANOL
Synonyms
2,3-Dihydro-1,4-benzodioxin-5-methanol;1,4-Benzodioxin-5-methanol, 2,3-dihydro-;2,3-Dihydro-1,4-benzodioxan-5-ylmethanol;2,3-DIHYDRO-1,4-BENZODIOXIN-5-YLMETHANOL;(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)methanol;2,3-Dihydro-5-(hydroxymethyl)-1,4-benzodioxine;(2,3-Dihydro-1,4-benzodioxin-5-yl)methanol, 5-(Hydroxymethyl)-1,4-benzodioxane
CBNumber
CB6295244
Molecular Formula
C9H10O3
Formula Weight
166.17
MOL File
274910-19-9.mol
More
Less

2,3-DIHYDRO-1,4-BENZODIOXIN-5-YLMETHANOL Property

Melting point:
54 °C
Boiling point:
94-97 °C(Press: 0.28 Torr)
Density 
1.257±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
14.24±0.10(Predicted)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36-51
Safety Statements 
24/25-26
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FD139328
Product name
(2,3-Dihydrobenzo[b][1,4]dioxin-5-yl)methanol
Packaging
1g
Price
$78
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD139328
Product name
(2,3-Dihydrobenzo[b][1,4]dioxin-5-yl)methanol
Packaging
2g
Price
$136
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD139328
Product name
(2,3-Dihydrobenzo[b][1,4]dioxin-5-yl)methanol
Packaging
5G
Price
$271
Updated
2021/12/16
AK Scientific
Product number
Y8530
Product name
2,3-Dihydro-1,4-benzodioxin-5-ylmethanol
Packaging
5g
Price
$411
Updated
2021/12/16
Matrix Scientific
Product number
119575
Product name
(2,3-Dihydrobenzo[b][1,4]dioxin-5-yl)methanol
Purity
95+%
Packaging
250mg
Price
$414
Updated
2021/12/16
More
Less

2,3-DIHYDRO-1,4-BENZODIOXIN-5-YLMETHANOL Chemical Properties,Usage,Production

Synthesis

4442-53-9

274910-19-9

2,3-Dihydro-1,4-benzodiene-5-carboxylic acid (5.00 g, 28.0 mmol) was dissolved in tetrahydrofuran (150 mL) at 0 °C and lithium aluminum hydride (2.13 g, 56.0 mmol) was added slowly. The reaction mixture was stirred at 0 °C for 10 min, then brought to room temperature and continued stirring for 18 h. The reaction was completed by the addition of water (2.13 g, 56.0 mmol). Upon completion of the reaction, the reaction was quenched by the addition of water (150 mL) and subsequently extracted with ethyl acetate (2 x 100 mL). The organic phases were combined, washed with saturated saline (100 mL), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford the target product (2,3-dihydrobenzo[b][1,4]dioxin-5-yl)methanol as a yellow oil (3.22 g, 99% yield). The product was characterized by 1H NMR (CDCl3): δ 6.87-6.79 (m, 3H), 4.66 (s, 2H), 4.32-4.30 (m, 2H), 4.28-4.25 (m, 2H), 2.19 (bs, 1H). The [M+H-18]+ peak was detected by mass spectrometry, m/z = 149.5.

References

[1] Patent: WO2017/155909, 2017, A1. Location in patent: Paragraph 0075
[2] Bioorganic and Medicinal Chemistry, 2018, vol. 26, # 8, p. 1797 - 1809

2,3-DIHYDRO-1,4-BENZODIOXIN-5-YLMETHANOL Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2,3-DIHYDRO-1,4-BENZODIOXIN-5-YLMETHANOL Suppliers

Belgium 1 China 52 Germany 2 India 2 United Kingdom 2 United States 11 Global 70
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
ZHIWE CHEMTECH CO LTD
Tel
021-20221225 13917446399
Fax
QQ:115820162
Email
zwchem@163.com
Country
China
ProdList
617
Advantage
61
Amber MolTech LLC
Tel
086-010-62176588
Fax
086-010-62117849
Email
amber@jyamber.com
Country
China
ProdList
10151
Advantage
56
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9793
Advantage
50
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Shanghai Chenzhu Pharmaceutical Co., Ltd.
Tel
13162380607
Fax
QQ:1696175688
Email
1696175688@qq.com
Country
China
ProdList
817
Advantage
55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Yantai ShengKailun Chemical Technology Co., Ltd.
Tel
13356901049
Fax
QQ：1025383091
Email
3119594100@qq.com
Country
China
ProdList
7964
Advantage
55
Sichuan BaiPeng Biotechnology Co., Ltd.
Tel
028-65791793 18140026355
Fax
QQ568470422
Email
568470422@qq.com
Country
China
ProdList
9997
Advantage
58
Aikon International Limited
Tel
025-58859352 18068836627
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15083
Advantage
58
Suzhou Nuoouman Biological Technology Co., Ltd.
Tel
15026866316
Email
180642609@qq.com
Country
China
ProdList
4967
Advantage
58
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400-6387771-6039 18920764717
Email
sales@heowns.com
Country
China
ProdList
23771
Advantage
60
Henan Alfachem Co.,Ltd.
Tel
0371-55051623 18137891487
Fax
QQ：2853979817
Email
2853979817@qq.com
Country
China
ProdList
9988
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57422
Advantage
58
Zhejiang J&C Biological Technology Co.,Limited
Tel
+1-2135480471
Email
sales@sarms4muscle.com
Country
China
ProdList
10473
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
+86-0571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52846
Advantage
58
Zhejiang Lianshuo Biotechnology Co., Ltd.
Tel
18616526224
Email
lianshuo@vip.126.com
Country
China
ProdList
9607
Advantage
58
Beijing xinyanhui pharmaceutical research and development co., LTD
Tel
13969155946
Email
1461866103@qq.com
Country
China
ProdList
16111
Advantage
58
Changzhou Yinghao Technology Development Co., Ltd
Tel
15151934985
Email
sales@yingsapharm.com
Country
China
ProdList
5181
Advantage
58
Zhengzhou anmousse chemical products co. LTD
Tel
0371-55289822 18737195735
Fax
QQ:483339295
Email
483339295@qq.com
Country
China
ProdList
7587
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49975
Advantage
58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
Tel
+8613580539051
Email
joe@yuhengpharm.com
Country
CHINA
ProdList
21142
Advantage
58
Changzhou Kechem Bio-Scientific Co., LTD.
Tel
0519-68985668 13685222090
Fax
qq735434464
Email
sales@kechem.cn
Country
China
ProdList
26028
Advantage
58
Shanghai Xiushi Biomedical Co., LTD
Tel
15002184385 15021598081 15002184385
Email
product001@xiushipharm.com
Country
China
ProdList
4719
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
Tel
021-51816796-820 13611835272
Fax
021-5161 3951
Email
sales2@sunwaypharm.com
Country
China
ProdList
44119
Advantage
58
Hubei Co-prosperity Medicine Technonlogy Co., Ltd
Tel
2383948258 19172820304
Email
2383948258@qq.com
Country
China
ProdList
12987
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2815987 13927875076
Fax
0751-2828607
Email
3007432263@qq.com
Country
China
ProdList
9963
Advantage
58
Bide Pharmatech Ltd.
Tel
400-6005915
Email
sales@picasso-e.com
Country
China
ProdList
39653
Advantage
58
Shanghai Lingfu Pharmaceutical Research Co. LTD
Tel
+86(21)5895 0110 19945755304
Email
sales@chemany.com
Country
China
ProdList
9984
Advantage
58
Shandong Welt Chem. Co.,Ltd.
Tel
531-87153728 13805401165
Email
xufeng192@126.com
Country
China
ProdList
3964
Advantage
58
Hangzhou Hongxi Biomedical Technology Co., LTD
Tel
18989489206
Email
hoxipharm@163.com
Country
China
ProdList
4921
Advantage
58
Yantai Sheng Kai Lun Biological Products Co. , Ltd.
Tel
13356901049
Email
mark@sklnchem.cn
Country
China
ProdList
7998
Advantage
58
Shanghai Haohong Scientific Co., Ltd.
Tel
400-8210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
40000
Advantage
58
Anhui Henuo Biotechnology Co., Ltd
Tel
18455579438
Country
China
ProdList
16684
Advantage
58
Shanghai Jieshikai Biotechnology Co. , Ltd.
Tel
021-57520305 13795461237
Email
zhuruyan@jskchem.com
Country
China
ProdList
49234
Advantage
58
Zhuhai Aobokai Biomedical Technology Co., Ltd.
Tel
400-0628126 18736790110;
Email
sales-team@aobchem.com.cn
Country
China
ProdList
50000
Advantage
58
https://hanhongsci.com/
Tel
021-54306202 18917919676
Email
info@hanhongsci.com
Country
China
ProdList
29995
Advantage
58
Yanggu Rongke Trading Co., Ltd
Tel
15863541132
Email
18366413387@163.com
Country
China
ProdList
3898
Advantage
58
Huanuo Pharmaceutical Technology (Guangxi) Co., Ltd
Tel
13005928603
Email
211017228@qq.com
Country
China
ProdList
8277
Advantage
58
Beijing Famozi Pharmaceutical Technology Co., Ltd
Tel
15811073878
Email
2559355526@qq.com
Country
China
ProdList
10000
Advantage
58
Hangzhou Boloko Biotechnology Co., LTD
Tel
13757158499; 13757158499
Email
bolokobiotech@qq.com
Country
China
ProdList
3981
Advantage
58
Heze Xingda Pharmaceutical Technology Co., Ltd.
Tel
13583079096
Email
18366413387@163.com
Country
China
ProdList
3881
Advantage
58
GIHI CHEMICALS CO.,LIMITED
Tel
+8618058761490
Email
info@gihichemicals.com
Country
China
ProdList
49941
Advantage
58
PT CHEM GROUP LIMITED
Tel
+86-85511178;
Email
peter68@ptchemgroup.com
Country
China
ProdList
35425
Advantage
58
Beijing Boning Biotechnology Co., Ltd.
Tel
13269979963
Email
1565439254@qq.com
Country
CHINA
ProdList
195
Advantage
58

274910-19-9, 2,3-DIHYDRO-1,4-BENZODIOXIN-5-YLMETHANOLRelated Search:

3-OXO-INDAN-4-CARBOXYLIC ACID 2,3-dihydro-1-oxo-1H-indene-4-carbonitrile 2-PHENYL-2,3-DIHYDRO-4-QUINOLONE 2,3-DIHYDRO-1,4-BENZODIOXIN-6-YLMETHANOL 2,3-DIHYDRO-1,4-BENZODIOXIN-2-YLMETHANOL 2,3-Dihydro-1,4-benzodioxine-5-carboxylic acid 8-Amino-7-chloro-2,3-dihydrobenzo[1,4]dioxine-5-carboxylic acid ethyl ester 6,7-Dibromo-2,3-dihydrobenzo[1,4]dioxine-5-carboxylic acid 6,7-Dibromo-8-nitro-2,3-dihydrobenzo[1,4]dioxine-5-carboxylic acid 8-Amino-2,3-dihydrobenzo[1,4]dioxine-5-carboxylic acid ethyl ester 8-Amino-2,3-dihydrobenzo[1,4]dioxine-5-carboxylic acid 2,3-DIHYDRO-1,4-BENZODIOXIN-5-YLMETHANOL 7-Bromo-2,3-dihydrobenzo[1,4]dioxine-5-carboxylic acid ethyl ester 1,4-Benzodioxin-5-carboxylic acid, 2,3-dihydro-8-(2-(hydroxymethyl)-3- (4-(1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl)-1-piperazinyl)propoxy )-, 3-methylbutyl ester, monohydrochloride (8-Amino-2,3-dihydrobenzo[1,4]dioxin-5-yl)-methanol 7-(chlorosulfonyl)-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid 1-BUTYL-4-PIPERIDINYLMETHYL-8-AMINO-7-CHLORO-2,3-DIHYDRO-1,4-BENZODIOXIN-5-CARBOXYLATE HYDROCHLORIDE 7-Iodo-2,3-dihydrobenzo[1,4]dioxine-5-carboxylic acid ethyl ester

  • 2,3-DIHYDRO-1,4-BENZODIOXIN-5-YLMETHANOL
  • 2,3-Dihydro-5-(hydroxymethyl)-1,4-benzodioxine
  • (2,3-Dihydro-1,4-benzodioxin-5-yl)methanol, 5-(Hydroxymethyl)-1,4-benzodioxane
  • (2,3-dihydrobenzo[b][1,4]dioxin-5-yl)methanol
  • 2,3-Dihydro-1,4-benzodioxin-5-methanol
  • 2,3-Dihydro-1,4-benzodioxan-5-ylmethanol
  • 1,4-Benzodioxin-5-methanol, 2,3-dihydro-
  • 274910-19-9