ANTI-8-HYDROXYGUANOSINE

Product Name
ANTI-8-HYDROXYGUANOSINE
Chemical Name
ANTI-8-HYDROXYGUANOSINE
Synonyms
Anti-8OHG;ANTI-8OHDG;ANTI-8-OHG GOAT PAB;Anti-DNA/RNA Damage;ANTI-8-OXO-G GOAT PAB;ANTI-8-HYDROXYGUANOSINE;ANTI-8-HYDROXYGUANOSINE GOAT PAB;Monoclonal Anti-DNA/RNA Damage antibody produced in mouse
CBNumber
CB6298179
Molecular Formula
C10H13N5O6
Formula Weight
299.24012
MOL File
Mol file
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ANTI-8-HYDROXYGUANOSINE Property

storage temp. 
-20°C
form 
buffered aqueous glycerol solution
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Safety

WGK Germany 
1
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
DR1001
Product name
Anti-8-Hydroxyguanosine Goat pAb
Purity
liquid, Calbiochem?
Packaging
100μL
Price
$458
Updated
2024/03/01
Sigma-Aldrich
Product number
SAB5200010
Product name
Monoclonal Anti-DNA/RNA Damage antibody produced in mouse
Purity
clone 15A3, 1?mg/mL, purified immunoglobulin
Packaging
100μG
Price
$503
Updated
2023/06/20
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ANTI-8-HYDROXYGUANOSINE Chemical Properties,Usage,Production

General Description

DNA/RNA damage, also known as 8-hydroxyguanine (8-OHG), is a product of oxidized DNA or RNA.

Biochem/physiol Actions

8-hydroxyguanine (8-OHG) helps in determining the reactive oxygen species (ROS)-induced modification of a purine residue in DNA. It is a sensitive marker of oxidative DNA damage. Overexpression of the gene has been observed in diabetic patients, especially those with advanced microvascular complications. Thus, 8-OHG functions as a novel biomarker for identifying oxidative DNA damage in diabetic patients. Plasma level of 8-OHG elevates with the age, with cigarette smoking and during tumorigenesis. 8-OHG levels in urine is considered as a biomarker of the total systemic oxidative stress in vivo. Overexpression of 8-OHG has been observed in various neurodegenerative diseases such as Parkinson′s disease (PD) and multiple system atrophy (MSA).

ANTI-8-HYDROXYGUANOSINE Preparation Products And Raw materials

Raw materials

Preparation Products

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ANTI-8-HYDROXYGUANOSINE Suppliers

Switzerland 1 United States 3 Global 4
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
EMD Biosciences, Inc.
Tel
--
Fax
--
Email
technical@calbiochem.com
Country
United States
ProdList
6529
Advantage
66
BIODESIGN International/OEM Concepts
Tel
--
Fax
--
Email
info@biodesign.com
Country
United States
ProdList
2376
Advantage
50

ANTI-8-HYDROXYGUANOSINERelated Search:

8-HYDROXYGUANOSINE

  • ANTI-8-HYDROXYGUANOSINE
  • ANTI-8-HYDROXYGUANOSINE GOAT PAB
  • ANTI-8OHDG
  • ANTI-8-OHG GOAT PAB
  • ANTI-8-OXO-G GOAT PAB
  • Anti-8OHG
  • Anti-DNA/RNA Damage
  • Monoclonal Anti-DNA/RNA Damage antibody produced in mouse