4,5-DIMETHOXY-ISATOIC ANHYDRIDE
- Product Name
- 4,5-DIMETHOXY-ISATOIC ANHYDRIDE
- CAS No.
- 20197-92-6
- Chemical Name
- 4,5-DIMETHOXY-ISATOIC ANHYDRIDE
- Synonyms
- 6,7-DIMETHOXYISATOIC ANHYDRIDE;4,5-DIMETHOXY-ISATOIC ANHYDRIDE;6,7-dimethoxy-2H-3,1-benzoxazine-2,4(1H)-dione;6,7-DIMETHOXY-1H-BENZO[D][1,3]OXAZINE-2,4-DIONE;4,5-Dimethoxy-isatoic anhydride, CAS 20197-92-6;2H-3,1-Benzoxazine-2,4(1H)-dione, 6,7-dimethoxy-;6,7-Dimethoxy-2,4-dihydro-1H-3,1-benzoxazine-2,4-dione;4,5-DIMETHOXY-ISATOIC ANHYDRIDE4,5-DIMETHOXY-ISATOIC ANHYDRIDE
- CBNumber
- CB6298634
- Molecular Formula
- C10H9NO5
- Formula Weight
- 223.18
- MOL File
- 20197-92-6.mol
4,5-DIMETHOXY-ISATOIC ANHYDRIDE Property
- Melting point:
- 255 °C(Solv: 1,4-dioxane (123-91-1))
- Density
- 1.358±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 9.93±0.20(Predicted)
- color
- Pale Beige to Light Beige
- CAS DataBase Reference
- 20197-92-6(CAS DataBase Reference)
Safety
- HazardClass
- IRRITANT
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- D470613
- Product name
- 4,5-Dimethoxyisatoicanhydride
- Packaging
- 250mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 011695
- Product name
- 4,5-Dimethoxy-isatoicanhydride
- Purity
- 95%
- Packaging
- 250mg
- Price
- $19
- Updated
- 2021/12/16
- Product number
- 011695
- Product name
- 4,5-Dimethoxy-isatoicanhydride
- Purity
- 95%
- Packaging
- 1g
- Price
- $28
- Updated
- 2021/12/16
- Product number
- 039854
- Product name
- 6,7-Dimethoxy-2H-3,1-benzoxazine-2,4(1H)-dione
- Packaging
- 1g
- Price
- $39
- Updated
- 2021/12/16
- Product number
- 039854
- Product name
- 6,7-Dimethoxy-2H-3,1-benzoxazine-2,4(1H)-dione
- Packaging
- 5g
- Price
- $134
- Updated
- 2021/12/16
4,5-DIMETHOXY-ISATOIC ANHYDRIDE Chemical Properties,Usage,Production
Synthesis
501-53-1
5653-40-7
20197-92-6
The general procedure for the synthesis of 6,7-dimethoxy-2H-benzo[d][1,3]oxazine-2,4(1H)-diones from benzyl chloroformate and 2-amino-4,5-dimethoxybenzoic acid is as follows: 1. 2-Amino-4,5-dimethoxybenzoic acid (25 g, 0.13 mol) was dissolved in tetrahydrofuran (THF, 400 mL). 2. Benzyl chloroformate (54 mL, 0.38 mol) was added slowly with vigorous stirring. 3. The reaction mixture was refluxed overnight, followed by evaporation to dryness and further removal of residual solvent under vacuum. 4. Ether (425 mL) was added to the residue followed by phosphorus tribromide (PBr3, 11.88 mL, 0.13 mol). 5. The mixture was refluxed for 48 hours, after which the reaction mixture was filtered and the solid was washed with ether (3 × 150 mL). 6. The residue was redissolved in ether, stirred for 1 h and then filtered, washed and dried to give 27 g of a white powdery product, 6,7-dimethoxy-2H-benzo[d][1,3]oxazine-2,4(1H)-dione. Yield: 96%. 1H NMR (DMSO-d6, 200 MHz): δ 3.82 (s, 3H, OCH3), 3.88 (s, 3H, OCH3), 6.66 (s, 1H, Ar), 7.27 (s, 1H, Ar), 11.58 (s, 1H, exchangeable NH).
References
[1] Patent: US2006/128695, 2006, A1. Location in patent: Page/Page column 20
4,5-DIMETHOXY-ISATOIC ANHYDRIDE Preparation Products And Raw materials
Raw materials
Preparation Products
4,5-DIMETHOXY-ISATOIC ANHYDRIDE Suppliers
- Tel
- --
- Fax
- --
- info@abcr.de
- Country
- Germany
- ProdList
- 6831
- Advantage
- 75
View Lastest Price from 4,5-DIMETHOXY-ISATOIC ANHYDRIDE manufacturers
- Product
- 4,5-DIMETHOXY-ISATOIC ANHYDRIDE 20197-92-6
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2020-02-04