4-Azido-L-phenylalanine

Product Name: 4-Azido-L-phenylalanine
CAS No.: 33173-53-4
Chemical Name: 4-Azido-L-phenylalanine
Synonyms: H-PHE(4-N3)-OH;H-L-Phe(4-N3)-OH;H-4-Azido-Phe-OH;H-P-AZIDO-PHE-OH;L-Phe(4-azido)-OH;H-PHE(4-AZIDO)-OH;H-P-AZIDO-L-PHE-OH;p-azidophenylanaline;4-azidophenylalanine;P-AZIDO-PHENYLALANINE
CBNumber: CB6303989
Molecular Formula: C9H10N4O2
Formula Weight: 206.21
MOL File: 33173-53-4.mol

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4-Azido-L-phenylalanine Property

storage temp.: -20°C
solubility: Water : 6.2 mg/mL (30.07 mM; ultrasonic and adjust pH to 6 with HCl);DMSO : 6 mg/mL (29.10 mM; ultrasonic and adjust pH to 6 with HCl)
form: Solid
color: White to yellow
Appearance: off-white solid
InChI: InChI=1/C9H10N4O2/c10-8(9(14)15)5-6-1-3-7(4-2-6)12-13-11/h1-4,8H,5,10H2,(H,14,15)/t8-/s3
InChIKey: NEMHIKRLROONTL-SBYBRXNCNA-N
SMILES: C(C1C=CC(N=[N+]=[N-])=CC=1)[C@H](N)C(=O)O |&1:10,r|

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Safety

HS Code: 2922498590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: A3582
Product name: H-Phe(4-N3)-OH
Packaging: 250MG
Price: $200
Updated: 2025/07/31

TRC

Product number: A923015
Product name: 4-Azido-L-phenylalanine
Packaging: 25mg
Price: $65
Updated: 2021/12/16

Usbiological

Product number: 260709
Product name: 4-Azido-L-phenylalanine
Packaging: 100mg
Price: $363
Updated: 2021/12/16

Chem-Impex

Product number: 06162
Product name: 4-Azido-L-phenylalanine
Purity: ≥ 99.7% (Chiral HPLC)
Packaging: 100MG
Price: $65
Updated: 2021/12/16

Iris Biotech GmbH

Product number: HAA1850
Product name: H-L-Phe(4-N3)-OH
Packaging: 250mg
Price: $108
Updated: 2021/12/16

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4-Azido-L-phenylalanine Chemical Properties,Usage,Production

Description

4-Azido-L-phenylalanine (4AZP) is an unnatural amino acid analog of L-phenylalanine that contains an azide moiety. 4AZP-labeling is a fast, sensitive, and non-radioactive alternative to the traditional technique for detecting nascent protein synthesis.

4AZP is randomly incorporated into synthesizing protein instead of phenylalanine during translation. The resulting azide-labeled full-length proteins can be detected via copper-catalyzed click reaction (with fluorescent or biotin-labeled alkynes) or copper-free click reaction (with cycloalkynes) and used for subsequent microscopic imaging or purification tasks.

Chemical Properties

Off-white to brown powder

Uses

4-Azido-L-phenylalanine is an unnatural derivative of L-phenylalanine. It is a nonpolar, essential amino acid that naturally occurs in the human body and is also used to treat patients with depression.

Uses

The in-vivo incorporation of clickable unnatural amino acids such as 4-Azido-L-phenylalanine with unique reactivity at a defined postition is used for functionalization of proteins. The azide functionalities in the protein can then be modified with almost any alkyne bearing molecule by Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC). Copper-free alternatives with strained internal alkynes are also available (SPAAC). Some examples enabled with this technique are protein PEGylation, masking with sugars, and the attachment to antibodies.

reaction suitability

reaction type: click chemistry
reaction type: solution phase peptide synthesis

4-Azido-L-phenylalanine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Azido-L-phenylalanine Suppliers

China 97 France 1 Germany 1 India 2 Japan 1 United Kingdom 1 United States 12 Global 115

Shanghai Beckham Medical Technology Co., Ltd

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View Lastest Price from 4-Azido-L-phenylalanine manufacturers

Career Henan Chemica Co

Product: 4-Azido-L-phenylalanine 33173-53-4
Price: US $1.00/g
Min. Order: 1g
Purity: 85.0-99.8%
Supply Ability: 20ton
Release date: 2020-10-28

Xian confluore Biological Technology Co., Ltd.

Product: 4-Azido-L-phenylalanine 33173-53-4
Price: US $0.00/mg
Min. Order: 250mg
Purity: >95.00%
Supply Ability: 250mg
Release date: 2024-03-30

33173-53-4, 4-Azido-L-phenylalanineRelated Search:

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4-AZIDO-L-PHENYLALANINE

4-Azido-L-phenylalanine≥ 98% (HPLC)

L-Phe(4-azido)-OH

p-Azido-L-phenylalanine

P-AZIDO-PHENYLALANINE

4-azidophenylalanine

L-Phenylalanine, 4-azido-

(S)-2-aMino-3-(4-azidophenyl)propanoic acid

p-azidophenylanaline

H-4-Azido-Phe-OH

H-L-Phe(4-N3)-OH

4-Azido-L-phenylalanine HCl

(S)-2-AMINO-3-P-AZIDOPHENYLPROPIONIC ACID

H-PHE(4-AZIDO)-OH

H-P-AZIDO-L-PHE-OH

H-P-AZIDO-PHE-OH

H-PHE(4-N3)-OH

(2S)-2-amino-3-(4-azidophenyl)propanoic acid

(S)-2-amino-3-(4-azidophenyl)propanoic acid 4-Azido-L-phenylalanine

(2S)-2-amino-3-(4-azidophenyl)propanoicaci

4-Azido-<sc>L</sc>-phenylalanine

4-Azido-L-phenylalanine (CCT-1406)

33173-53-4