ChemicalBook > CAS DataBase List > (R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline

(R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline

Product Name
(R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline
CAS No.
85-63-2
Chemical Name
(R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline
Synonyms
(-)-laudanosine;Impurities of atracurium391;cis-Atracurium EP Impurity C;(R)-1-(3,4-dimethoxybenzyl)-;AtracuriuM Besylate iMpurity C;Cisatracurium Besilate Impurity 3;Cisatracurium Besilate EP Impurity C;Cisatracurium Besilate EP Impurity C (R-Laudanosine);(R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline;(1R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline
CBNumber
CB63040993
Molecular Formula
C21H27NO4
Formula Weight
357.44
MOL File
85-63-2.mol
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(R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline Property

solubility 
Chloroform (Slightly), DMSO (Slightly, Sonicated), Ethanol (Slightly), Methanol
form 
Solid
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Medical Isotopes, Inc.
Product number
52004
Product name
(R)-Laudanosine
Packaging
5G
Price
$2200
Updated
2021/12/16
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(R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline Chemical Properties,Usage,Production

Uses

(R)-Laudanosine is an isomer of (S)-Laudanosine (L178525), a metabolite of the neuromuscular-blocking drugs Atracurium (A794500) and Cisatracurium (C496700) with potentially toxic systemic effects. It crosses the blood-brain barrier and may cause excitement and seizure activity.

Definition

ChEBI: (R)-laudanosine is a benzylisoquinoline alkaloid that is (R)-tetrahydropapaverine in which the amino hydrogen has been replaced by a methyl group It is a polyether, a benzylisoquinoline alkaloid, a benzyltetrahydroisoquinoline, an aromatic ether and a tertiary amino compound. It is functionally related to a (R)-tetrahydropapaverine. It is a conjugate base of a (R)-laudanosine(1+).

(R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline Suppliers

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85-63-2, (R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolineRelated Search:


  • (1R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline
  • (R)-1-(3,4-dimethoxybenzyl)-
  • cis-Atracurium EP Impurity C
  • Cisatracurium Besilate EP Impurity C
  • AtracuriuM Besylate iMpurity C
  • Cisatracurium Besilate EP Impurity C (R-Laudanosine)
  • Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (1R)-
  • (R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium
  • (-)-laudanosine
  • Impurities of atracurium391
  • Cisatracurium Besilate Impurity 3
  • (R)-1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline (Cisatracurium Besilate Impurity)
  • (R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline
  • 85-63-2