MSI-1436

Product Name: MSI-1436
CAS No.: 186139-09-3
Chemical Name: MSI-1436
Synonyms: MSI-1436;Trodusquemine;MSI 1436,MSI1436;MSI-1436 USP/EP/BP;MSI-1436(Trodusquemine;Trodusquemine (MSI-1436);TRODUSQUEMINE;AMINOSTEROL-1436;MSI1436;Cholestane-7,24-diol, 3-[[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]amino]-, 24-(hydrogen sulfate), (3β,5α,7α,24R)-
CBNumber: CB63041435
Molecular Formula: C37H72N4O5S
Formula Weight: 685.07
MOL File: 186139-09-3.mol

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MSI-1436 Property

Density: 1.12±0.1 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
solubility: Soluble in DMSO
pka: -3.49±0.18(Predicted)
form: Solid
color: White to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: T891970
Product name: Trodusquemine
Packaging: 10mg
Price: $2100
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611475
Product name: MSI-1436
Packaging: 5mg
Price: $1149.2
Updated: 2021/12/16

ChemScene

Product number: CS-4937
Product name: MSI-1436
Packaging: 10mg
Price: $1920
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611475
Product name: MSI-1436
Packaging: 10mg
Price: $1921
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0004520
Product name: MSI-1436
Purity: 95.00%
Packaging: 5MG
Price: $2045.78
Updated: 2021/12/16

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MSI-1436 Chemical Properties,Usage,Production

Uses

Treatment of medically significant obesity.

Uses

Trodusquemine is a specific protein tyrosine phosphatase 1B (PTP1B) inhibitor.

Definition

ChEBI: Trodusquemine is a bile acid.

in vivo

MSI-1436 (10 mg/kg, i.p.) causes obesity-dependent body weight, reduces total body fat content and adipocyte size and lipid content of white adipose tissue of mice. MSI-1436 treatment significantly reduces plasma insulin levels. MSI-1436 (10 mg/kg, i.p.) increases phosphorylation of STAT-3 2.7-fold and, in conjunction with 100 U/kg insulin, p-IRβ increases threefold over insulin alone-treated rats^[1]. MSI-1436 (Trodusquemine) exhibits anxiolytic effect through a restoration of endocannabinoid (eCB) signaling within the amygdala^[2]. MSI-1436 (5 mg/kg, i.p.) has an anti-diabetic effect on diabetic mice, and is sufficient to suppress food intake and cause weight loss in CD1 mice^[3].

MSI-1436 Preparation Products And Raw materials

Raw materials

Preparation Products

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MSI-1436 Suppliers

China 25 United States 5 Global 30

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3506
Advantage: 58

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

Nanjing Meihao Pharmaceutical Technology Co., Ltd.

Tel: meitaochem@126.com
Email: meitaochem@126.com
Country: China
ProdList: 19103
Advantage: 58

Zhejiang J&C Biological Technology Co.,Limited

Tel: +1-2135480471
Email: sales@sarms4muscle.com
Country: China
ProdList: 10473
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 20284
Advantage: 58

HANGZHOU CLAP TECHNOLOGY CO.,LTD

Tel: 86-571-88216897,88216896 13588875226
Fax: 86-571-88216895
Email: sales@hzclap.com
Country: CHINA
ProdList: 6312
Advantage: 58

Beijing xinyanhui pharmaceutical research and development co., LTD

Tel: 13969155946
Email: 1461866103@qq.com
Country: China
ProdList: 16111
Advantage: 58

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View Lastest Price from MSI-1436 manufacturers

RongNa Biotechnology Co.,Ltd

Product: MSI-1436;Trodusquemine 186139-09-3
Price: US $10.00/ASSAYS
Min. Order: 1ASSAYS
Purity: 99%
Supply Ability: 1 ton
Release date: 2025-08-16

Shaanxi Dideu New Materials Co. Ltd

Product: Trodusquemine 186139-09-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-07-05

Dideu Industries Group Limited

Product: MSI-1436 186139-09-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-08-17

186139-09-3, MSI-1436Related Search:

MSI-1436

Trodusquemine

TRODUSQUEMINE;AMINOSTEROL-1436;MSI1436

Cholestane-7,24-diol, 3-[[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]amino]-, 24-(hydrogen sulfate), (3β,5α,7α,24R)-

Trodusquemine (MSI-1436)

MSI-1436 USP/EP/BP

MSI-1436(Trodusquemine

MSI 1436,MSI1436

186139-09-3

C37H72N4O5S