ChemicalBook > CAS DataBase List > CPI-268456

CPI-268456

Product Name
CPI-268456
CAS No.
1380087-86-4
Chemical Name
CPI-268456
Synonyms
CPI-268456;CPI 268456;CPI268456;4H-Isoxazolo[5,4-d][2]benzazepine-4-acetamide, 8-chloro-6-(4-chlorophenyl)-1-methyl-, (4S)-;2-((4R)-8-chloro-6-(4-chlorophenyl)-1-methyl-4H-benzo[c]isoxazolo[4,5-e]azepin-4-yl)acetamide;2-[(7S)-12-chloro-9-(4-chlorophenyl)-3-methyl-5-oxa-4,8-diazatricyclo[8.4.0.02,?]tetradeca-1(14),2(6),3,8,10,12-hexaen-7-yl]acetamide
CBNumber
CB63051827
Molecular Formula
C20H15Cl2N3O2
Formula Weight
400.258
MOL File
1380087-86-4.mol
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CPI-268456 Property

Boiling point:
649.8±55.0 °C(Predicted)
Density 
1.49±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml
form 
A crystalline solid
pka
16.03±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
20973
Product name
CPI-268456
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
20973
Product name
CPI-268456
Packaging
5mg
Price
$139
Updated
2024/03/01
Cayman Chemical
Product number
20973
Product name
CPI-268456
Packaging
10mg
Price
$243
Updated
2024/03/01
Cayman Chemical
Product number
20973
Product name
CPI-268456
Packaging
25mg
Price
$533
Updated
2024/03/01
DC Chemicals
Product number
DC8619
Product name
CPI-268456
Purity
>98%
Packaging
100mg
Price
$650
Updated
2021/12/16
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CPI-268456 Chemical Properties,Usage,Production

Uses

BRD4-IN-3 (compound 141) is a potent BRD4 inhibitor with an IC50 of <0.5 μM. BRD4-IN-3 shows cytoxicity for MYC-Raji with an IC50 value of >1 μM[1].

IC 50

BRD4: <0.5 μM (IC50)

References

[1] Brian K. Albrecht, et al. Bromodomain inhibitors and uses thereof. WO2012075383A2.

CPI-268456 Preparation Products And Raw materials

Raw materials

Preparation Products

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CPI-268456 Suppliers

China 33 United States 3 Global 36
Shanghai Boyle Chemical Co., Ltd.
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Shanghai Lollane Biological Technology Co.,Ltd.
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021-52996696，15000506266 15000506266
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+86-21-52996696
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Twochem Co.Ltd
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021-021-58111628 15800915896
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Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627
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ShangHai Biochempartner Co.,Ltd
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177-54423994 17754423994
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Amadis Chemical Company Limited
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Medi-tech Bioscientific Co., Ltd.
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Zhejiang J&C Biological Technology Co.,Limited
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Career Henan Chemica Co
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Absin Bioscience Inc.
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1380087-86-4, CPI-268456Related Search:


  • CPI-268456
  • 2-((4R)-8-chloro-6-(4-chlorophenyl)-1-methyl-4H-benzo[c]isoxazolo[4,5-e]azepin-4-yl)acetamide
  • CPI 268456;CPI268456
  • 4H-Isoxazolo[5,4-d][2]benzazepine-4-acetamide, 8-chloro-6-(4-chlorophenyl)-1-methyl-, (4S)-
  • 2-[(7S)-12-chloro-9-(4-chlorophenyl)-3-methyl-5-oxa-4,8-diazatricyclo[8.4.0.02,?]tetradeca-1(14),2(6),3,8,10,12-hexaen-7-yl]acetamide
  • 1380087-86-4