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Centrinone-B

Product Name
Centrinone-B
CAS No.
1798871-31-4
Chemical Name
Centrinone-B
Synonyms
LCR-323;Centrinone-B;Centrinone B,CentrinoneB;2-((2-Fluoro-4-((2-fluoro-3-nitrobenzyl)sulfonyl)phenyl)thio)-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(piperidin-1-yl)pyrimidin-4-amine;2-[[2-Fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(1-piperidinyl)-4-pyrimidinamine;4-Pyrimidinamine, 2-[[2-fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(1-piperidinyl)-
CBNumber
CB63067004
Molecular Formula
C27H27F2N7O5S2
Formula Weight
631.67
MOL File
1798871-31-4.mol
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Centrinone-B Property

Boiling point:
904.9±75.0 °C(Predicted)
Density 
1.54±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : 8.5 mg/mL (13.46 mM)
form 
Solid
pka
13.68±0.10(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Tocris
Product number
5690
Product name
CentrinoneB
Purity
≥98%(HPLC)
Packaging
10
Price
$259
Updated
2021/12/16
TRC
Product number
C256610
Product name
Centrinone-B
Packaging
1mg
Price
$130
Updated
2021/12/16
TRC
Product number
C256610
Product name
Centrinone-B
Packaging
5mg
Price
$500
Updated
2021/12/16
TRC
Product number
C256610
Product name
Centrinone-B
Packaging
10mg
Price
$1495
Updated
2021/12/16
ChemScene
Product number
CS-5374
Product name
Centrinone-B
Purity
98.97%
Packaging
5mg
Price
$144
Updated
2021/12/16
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Centrinone-B Chemical Properties,Usage,Production

Uses

Centrinone-B is a high affinity and selective PLK4 inhibitor. It depletes centriole and centrosome levels in vitro and induces cell cycle arrest in normal human cell lines in a p53-dependent manner.

storage

Store at -20°C

Centrinone-B Preparation Products And Raw materials

Raw materials

Preparation Products

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1798871-31-4, Centrinone-BRelated Search:


  • 2-[[2-Fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(1-piperidinyl)-4-pyrimidinamine
  • Centrinone-B
  • LCR-323
  • 4-Pyrimidinamine, 2-[[2-fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(1-piperidinyl)-
  • Centrinone B,CentrinoneB
  • 2-((2-Fluoro-4-((2-fluoro-3-nitrobenzyl)sulfonyl)phenyl)thio)-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(piperidin-1-yl)pyrimidin-4-amine
  • 1798871-31-4
  • C27H27F2N7O5S2