PKR-IN-2
- Product Name
- PKR-IN-2
- CAS No.
- 1628428-01-2
- Chemical Name
- PKR-IN-2
- Synonyms
- AG519;PKR-IN-2;PKR inhibitor 2;PKR activator 3;PKR-IN-2 ,E2388;PKR-IN-2, 10 mM in DMSO;pyruvate,PKRIN2,Pyruvate Kinase,kinase,PKR IN 2,inhibit,Inhibitor,deficiency;N-(4-(4-hydroxy-4-isobutylpiperidine-1-carbonyl)phenyl)quinoxaline-5-sulfonamide;5-Quinoxalinesulfonamide, N-[4-[[4-hydroxy-4-(2-methylpropyl)-1-piperidinyl]carbonyl]phenyl]-
- CBNumber
- CB63067019
- Molecular Formula
- C24H28N4O4S
- Formula Weight
- 468.57
- MOL File
- 1628428-01-2.mol
PKR-IN-2 Property
- Boiling point:
- 681.5±65.0 °C(Predicted)
- Density
- 1.336±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 50 mg/mL (106.71 mM)
- form
- Solid
- pka
- 6.11±0.50(Predicted)
- color
- White to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CS-5353
- Product name
- PKR-IN-2
- Purity
- 99.97%
- Packaging
- 5mg
- Price
- $420
- Updated
- 2021/12/16
- Product number
- CS-5353
- Product name
- PKR-IN-2
- Purity
- 99.97%
- Packaging
- 10mg
- Price
- $600
- Updated
- 2021/12/16
- Product number
- CS-5353
- Product name
- PKR-IN-2
- Purity
- 99.97%
- Packaging
- 50mg
- Price
- $1800
- Updated
- 2021/12/16
- Product number
- CS-5353
- Product name
- PKR-IN-2
- Purity
- 99.97%
- Packaging
- 100mg
- Price
- $2520
- Updated
- 2021/12/16
- Product number
- CD31003122
- Product name
- PKR-IN-2
- Purity
- 98+%
- Packaging
- 5mg
- Price
- $243
- Updated
- 2021/12/16
PKR-IN-2 Chemical Properties,Usage,Production
Uses
PKR activator 3 is a pyruvate kinase isoform PKR activator extracted from patent WO2014139144A1, compound 160. PKR activator 3 can be used for the research of PKR function related diseases, including cancer, diabetes, obesity, autoimmune disorders, and benign prostatic hyperplasia[1].
References
[1] Popovici-Muller, et al. Preparation of N-(piperidinecarbonylphenyl) sulfonamide compounds as pyruvate kinase modulators. From PCT Int. Appl. (2014), WO2014139144A1 20140918.
PKR-IN-2 Preparation Products And Raw materials
Raw materials
Preparation Products
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