ChemicalBook > CAS DataBase List > 2-(4-FORMYL-2-METHOXY-PHENOXY)-ACETAMIDE

2-(4-FORMYL-2-METHOXY-PHENOXY)-ACETAMIDE

Product Name
2-(4-FORMYL-2-METHOXY-PHENOXY)-ACETAMIDE
CAS No.
186685-89-2
Chemical Name
2-(4-FORMYL-2-METHOXY-PHENOXY)-ACETAMIDE
Synonyms
AKOS B000358;AKOS BBS-00006760;ART-CHEM-BB B000358;CHEMBRDG-BB 4132412;TIMTEC-BB SBB009162;2-(4-Formyl-2-methoxyphenoxy);4-CARBAMOYLMETHOXY-3-METHOXYBENZALDEHYDE;2-(4-FORMYL-2-METHOXY-PHENOXY)-ACETAMIDE;Acetamide, 2-(4-formyl-2-methoxyphenoxy)-;4-(2-Amino-2-oxoethoxy)-3-methoxybenzaldehyde
CBNumber
CB6308641
Molecular Formula
C10H11NO4
Formula Weight
209.2
MOL File
186685-89-2.mol
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2-(4-FORMYL-2-METHOXY-PHENOXY)-ACETAMIDE Property

Melting point:
84-85 °C(Solv: benzene (71-43-2))
Boiling point:
452.0±35.0 °C(Predicted)
Density 
1.257±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
15.30±0.40(Predicted)
Appearance
Off-white to light yellow Solid
CAS DataBase Reference
186685-89-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
HazardClass 
IRRITANT
HS Code 
2912490090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R396702
Product name
2-(4-FORMYL-2-METHOXY-PHENOXY)-ACETAMIDE
Purity
Aldrich<sup>CPR</sup>
Packaging
1 unit
Price
$30.7
Updated
2025/07/31
Sigma-Aldrich
Product number
R396702
Product name
2-(4-FORMYL-2-METHOXY-PHENOXY)-ACETAMIDE
Purity
AldrichCPR
Packaging
50MG
Price
$29.8
Updated
2024/03/01
TRC
Product number
B414190
Product name
2-(4-Formyl-2-methoxyphenoxy)acetamide
Packaging
100mg
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
019377
Product name
2-(4-Formyl-2-methoxy-phenoxy)-acetamide
Packaging
500mg
Price
$25
Updated
2021/12/16
AK Scientific
Product number
6276AD
Product name
2-(4-Formyl-2-methoxy-phenoxy)-acetamide
Packaging
250mg
Price
$38
Updated
2021/12/16
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2-(4-FORMYL-2-METHOXY-PHENOXY)-ACETAMIDE Chemical Properties,Usage,Production

Synthesis

121-33-5

79-07-2

186685-89-2

General procedure for the synthesis of 2-(4-formyl-2-methoxyphenyl)acetamide from vanillin and chloroacetamide: In a solvent mixture of acetonitrile-DMF (20 mL, 8:2, v/v), chloroacetamide (0.010 mol), vanillin (0.011 mol), and potassium carbonate (2.00 g, 0.0145 mol) were sequentially added. The reaction mixture was heated and refluxed under stirring for 5-7 h. The progress of the reaction was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the solvent was removed by evaporation, the residue was treated with an appropriate amount of water and the precipitated solid was collected by filtration. The resulting precipitate was washed with 30% aqueous methanol and subsequently dried in air. The yield of the product 2-(4-formyl-2-methoxyphenyl)acetamide and its physicochemical properties are listed in Table 9.

References

[1] Russian Chemical Bulletin, 2015, vol. 64, # 2, p. 395 - 404
[2] Izv. Akad. Nauk, Ser. Khim., 2015, # 2, p. 395 - 404,10
[3] Russian Journal of General Chemistry, 2005, vol. 75, # 7, p. 1113 - 1124
[4] European Journal of Medicinal Chemistry, 2014, vol. 81, p. 1 - 14

2-(4-FORMYL-2-METHOXY-PHENOXY)-ACETAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(4-FORMYL-2-METHOXY-PHENOXY)-ACETAMIDE Suppliers

Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
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88
Fluorochem Ltd
Tel
--
Fax
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Email
vernam@fluorochem.co.uk
Country
United Kingdom
ProdList
6375
Advantage
65
Zerenex Molecular Limited
Tel
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Fax
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Email
sales@zerenex-molecular.com
Country
United Kingdom
ProdList
6204
Advantage
47
Fluorochem Ltd.
Tel
--
Fax
--
Email
enquiries@fluorochem.co.uk
Country
United Kingdom
ProdList
6401
Advantage
74
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View Lastest Price from 2-(4-FORMYL-2-METHOXY-PHENOXY)-ACETAMIDE manufacturers

Career Henan Chemical Co
Product
2-(4-FORMYL-2-METHOXY-PHENOXY)-ACETAMIDE 186685-89-2
Price
US $5.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2020-01-12