3-METHYL-2-OXOPENTANOIC ACID SODIUM SALT Property

Melting point:

204-206 °C(lit.)

storage temp. 

2-8°C

solubility 

Methanol (Slightly), Water (Sparingly, Sonicated)

form 

Solid

color 

White to Off-White

Odor

very mild fruity

BRN 

7779663

LogP

0.17

Safety

Hazard Codes 

Xn

Risk Statements 

22

WGK Germany 

3

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

3-METHYL-2-OXOPENTANOIC ACID SODIUM SALT Chemical Properties,Usage,Production

Uses

3-Methyl-2-oxopentanoic acid sodium salt may be used in chemical synthesis studies.

Uses

3-Methyl-2-oxovaleric Acid is an α-ketomonocarboxylic acid that triggers insulin release by acting upon receptor sites which differ from those occupied by amino acids. 4-Methyl-2-oxovaleric Acid is a n analogue of Isoleucine.

Biochem/physiol Actions

(±)-3-Methyl-2-oxovaleric acid sodium salt is a mixture of the D- and L-3-methyl-2-oxovaleric acids. 3-methyl-2-oxovaleric acid is used as a substrate to study the specificity, distribution and kinetics of α-keto acid dehydrogenases. α-keto-β-methylvaleric acid is used to inhibit the mitochondrial α-ketoglutarate dehydrogenase complex (KGDHC) to induce and study nerve cell death. α-keto-β-methylvaleric acid may be studied as a reactive oxygen scavenger.