2-NITRO-3-ACETYLAMINO-4-METHYLBENZOIC ACID
- Product Name
- 2-NITRO-3-ACETYLAMINO-4-METHYLBENZOIC ACID
- CAS No.
- 7356-52-7
- Chemical Name
- 2-NITRO-3-ACETYLAMINO-4-METHYLBENZOIC ACID
- Synonyms
- 3-Acetamido-4-methyl-2-nitrobenzoic acid;2-NITRO-3-ACETYLAMINO-4-METHYLBENZOIC ACID;3-Acetylamino-4-methyl-2-nitro-benzoic acid;Benzoic acid, 3-(acetylaMino)-4-Methyl-2-nitro-
- CBNumber
- CB6310714
- Molecular Formula
- C10H10N2O5
- Formula Weight
- 238.2
- MOL File
- 7356-52-7.mol
2-NITRO-3-ACETYLAMINO-4-METHYLBENZOIC ACID Property
- storage temp.
- Sealed in dry,Room Temperature
N-Bromosuccinimide Price
- Product number
- A144940
- Product name
- 3-Acetamido-4-methyl-2-nitrobenzoicacid
- Packaging
- 50mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FA153791
- Product name
- 3-Acetamido-4-methyl-2-nitrobenzoic acid
- Packaging
- 250mg
- Price
- $102.5
- Updated
- 2021/12/16
- Product number
- FA153791
- Product name
- 3-Acetamido-4-methyl-2-nitrobenzoic acid
- Packaging
- 500mg
- Price
- $180
- Updated
- 2021/12/16
- Product number
- 073300
- Product name
- 3-Acetamido-4-methyl-2-nitrobenzoic acid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $231
- Updated
- 2021/12/16
- Product number
- FA153791
- Product name
- 3-Acetamido-4-methyl-2-nitrobenzoic acid
- Packaging
- 100mg
- Price
- $52
- Updated
- 2021/12/16
2-NITRO-3-ACETYLAMINO-4-METHYLBENZOIC ACID Chemical Properties,Usage,Production
Synthesis
6946-14-1
7356-52-7
The general procedure for the synthesis of 3-acetamido-4-methyl-2-nitrobenzoic acid from 3-acetamido-4-methylbenzoic acid is as follows: in Example 42, 3-acetamido-4-methylbenzoic acid (205 g, 1061 mmol) was added in batches to stirred fuming nitric acid (1 L), keeping the reaction temperature at -5°C during the addition process and ensuring that the entire reaction temperature does not exceed 0 °C throughout the reaction. After the addition was completed, stirring of the reaction mixture was continued for 1 hour. Subsequently, crushed ice (2.5 kg) was added to the reaction mixture and stirring was continued for 30 minutes. At the end of the reaction, the precipitate formed was collected by filtration and washed thoroughly with water. The obtained filter cake was air-dried and suspended in 1 L of acetic acid at 65°C. The suspension was allowed to stand for 1 hour to naturally cool to room temperature and then filtered. The filtrate was washed with acetic acid and ether sequentially to finally obtain 3-acetamido-4-methyl-2-nitrobenzoic acid (160 g, 63% yield) as a white solid. Mass spectrometry analysis showed (M + H)+ of 239.
References
[1] Patent: WO2018/218070, 2018, A2. Location in patent: Page/Page column 181; 182
[2] Patent: WO2007/76092, 2007, A2. Location in patent: Page/Page column 71
[3] Patent: WO2015/27222, 2015, A2. Location in patent: Paragraph 0278
[4] Patent: WO2007/125405, 2007, A2. Location in patent: Page/Page column 27; 87
[5] Patent: US2004/167194, 2004, A1. Location in patent: Page 23
2-NITRO-3-ACETYLAMINO-4-METHYLBENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
2-NITRO-3-ACETYLAMINO-4-METHYLBENZOIC ACID Suppliers
- Tel
- 18270980682
- Fax
- 021 51613951
- mlcheng@sunwaypharm.cn
- Country
- China
- ProdList
- 8669
- Advantage
- 57
- Tel
- +86057186818502 13588463833
- Fax
- Pls mail us for more information!
- info@sagechem.com
- Country
- China
- ProdList
- 10266
- Advantage
- 58
- Tel
- 027-86697669 13986148687
- Fax
- 86-027-86697669
- sales@tcaschem.com
- Country
- China
- ProdList
- 3993
- Advantage
- 55
- Tel
- 021-31261262/ 49 (0)17662837245
- Fax
- (0)21-33250524
- sales@novochemy.com
- Country
- Germany
- ProdList
- 6328
- Advantage
- 58
- Tel
- 022-60131465 18920720807
- Fax
- 022-58558581
- zishan_1986@163.com
- Country
- China
- ProdList
- 743
- Advantage
- 58
- Tel
- 0512-0512-52358471 17715136450
- Fax
- 05125235 6881
- sales@shiyabiopharm.com
- Country
- China
- ProdList
- 12127
- Advantage
- 58
- Tel
- 0570-3081766 18357083060
- Fax
- 0570-3072337
- sales@qzamkbio.com
- Country
- China
- ProdList
- 1046
- Advantage
- 55
- Tel
- 526763801 13301653310
- Fax
- +86-21-51619052
- 526763801@qq.com
- Country
- China
- ProdList
- 9274
- Advantage
- 55
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 025-58859352 18068836627
- Fax
- (5)02557626880
- dt3@aikonchem.com
- Country
- China
- ProdList
- 15493
- Advantage
- 58
View Lastest Price from 2-NITRO-3-ACETYLAMINO-4-METHYLBENZOIC ACID manufacturers
- Product
- 2-NITRO-3-ACETYLAMINO-4-METHYLBENZOIC ACID 7356-52-7
- Price
- US $6.68/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg-1000kg
- Release date
- 2020-01-08