ChemicalBook > CAS DataBase List > (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one

(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one

Product Name
(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one
CAS No.
1700622-07-6
Chemical Name
(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one
Synonyms
Ezetimibe-9;Ezetimibe Impuriry I;(3R,4S)-1-(4-fluorophenyl);3?-(4-Methylphenyl)ezetimibe;4”DeFluoro-4”methyl-Ezetimibe;4-Desfluoro-4-methyl Ezetimibe;(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one;2-Azetidinone, 1-(4-fluorophenyl)-3-[(3S)-3-hydroxy-3-(4-methylphenyl)propyl]-4-(4-hydroxyphenyl)-, (3R,4S)-;(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one? (Ezetimibe Impurity）;Ezetimibe impuriry 11/ 4”DeFluoro-4”methyl-Ezetimibe/(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one
CBNumber
CB63128952
Molecular Formula
C25H24FNO3
Formula Weight
405.46
MOL File
1700622-07-6.mol
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(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one Property

Melting point:
161-164°C
Boiling point:
663.6±55.0 °C(Predicted)
Density 
1.271±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
9.72±0.30(Predicted)
color 
Off-White to Pale Beige
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D228860
Product name
4”DeFluoro-4”methyl-Ezetimibe
Packaging
5mg
Price
$180
Updated
2021/12/16
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(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one Chemical Properties,Usage,Production

Uses

4”DeFluoro-4”methyl-ezetimibe is a derivative of Ezetimibe (E975000), which is an antihyperlipoproteinemic and a cholesterol absorption inhibitor.

(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

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(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one Suppliers

China 38 India 1 United States 5 Global 44
Quality Control Solutions Ltd.
Tel
0755-66853366 13670046396
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0755-28363542
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orders@qcsrm.com
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China
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Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
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051085625359
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sales@reading-chemicals.com
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China
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Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9906
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50
BOC Sciences
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16314854226
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info@bocsci.com
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United States
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9923
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Roark Standards
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0755-83552066 15986688328
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0755-83552066
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service@roarkstandards.com
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China
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Shanghai Zhen Li Biological Technology Co., Ltd
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021-16621358918; 18516310516
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13045646768
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zhenlipharma888@163.com
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19065
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58
XinYao(Shenzhen) Biological Technology Co., Ltd.
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0755-89880280
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Hangzhou Huarong Pharm Co., Ltd.
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571-86758373 +8613588754946
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0086-571-81131109
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Guangzhou Dreampharm Biotechnology Co., Ltd.
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Standardpharm Co. Ltd.
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86-714-3992388
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1700622-07-6, (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-oneRelated Search:

(S)-3-((R)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one EzetiMibe Fluoro IsoMer (R)-3-((R)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one (3R,4R)-1-(4-fluorophenyl)-3-((R)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one EZETIMIBE-D4 5-(4-FLUOROPHENYL)VALERIC ACID (3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one (4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone EZM-K 4-Benzyloxybenzaldehyde (2R,3R,6S)-N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxaMide (S)-3-((2R,5R)-5-(4-fluorophenyl)-2-((S)-(4-fluorophenylaMino)(4-hydroxyphenyl)Methyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one (αR,δS)-4-Fluoro-N-(4-fluorophenyl)-δ-hydroxy-α-[(4-hydroxyphenyl)Methyl]benzenepentanaMide 4-(4-Fluorobenzoyl)butyric acid (3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one EzetiMibe Dehydoxy IMpurity Desfluoro EzetiMibe (3S,4S)-1-(4-fluorophenyl)-3-((R)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one

  • Ezetimibe impuriry 11/ 4”DeFluoro-4”methyl-Ezetimibe/(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one
  • (3R,4S)-1-(4-fluorophenyl)
  • Ezetimibe-9
  • (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one
  • 4-Desfluoro-4-methyl Ezetimibe
  • 4”DeFluoro-4”methyl-Ezetimibe
  • 2-Azetidinone, 1-(4-fluorophenyl)-3-[(3S)-3-hydroxy-3-(4-methylphenyl)propyl]-4-(4-hydroxyphenyl)-, (3R,4S)-
  • 3?-(4-Methylphenyl)ezetimibe
  • Ezetimibe Impuriry I
  • (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one? (Ezetimibe Impurity）
  • 1700622-07-6