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AZD3147

Product Name
AZD3147
CAS No.
1101810-02-9
Chemical Name
AZD3147
Synonyms
AZD3147;AZ-12600000;AZD 3147, 10 mM in DMSO;(S)-1-(4-(4-(1-(cyclopropylsulfonyl)cyclopropyl)-6-(3-methylmorpholino)pyrimidin-2-yl)phenyl)-3-(2-hydroxyethyl)thiourea;1-[4-[4-(1-cyclopropylsulfonylcyclopropyl)-6-[(3S)-3-methylmorpholin-4-yl]pyrimidin-2-yl]phenyl]-3-(2-hydroxyethyl)thiourea;(S)-1-(4-(4-(1-(Cyclopropylsulfonyl)cyclopropyl)-6-(3-methylmorpholin-4-yl)-pyrimidin-2-yl)phenyl)-3-(2-hydroxyethyl)thiourea;N-[4-[4-[1-(Cyclopropylsulfonyl)cyclopropyl]-6-[(3S)-3-methyl-4-morpholinyl]-2-pyrimidinyl]phenyl]-N'-(2-hydroxyethyl)thiourea;N-[4-[4-[1-(cyclopropylsulfonyl)cyclopropyl]-6-[(3S)-3-methyl-4-morpholinyl]-2-pyrimidinyl]phenyl]-N'-(2-hydroxyethyl)-thiourea;Thiourea, N-[4-[4-[1-(cyclopropylsulfonyl)cyclopropyl]-6-[(3S)-3-methyl-4-morpholinyl]-2-pyrimidinyl]phenyl]-N'-(2-hydroxyethyl)-
CBNumber
CB63134225
Molecular Formula
C24H31N5O4S2
Formula Weight
517.66
MOL File
1101810-02-9.mol
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AZD3147 Property

Boiling point:
696.7±65.0 °C(Predicted)
Density 
1.45±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: <100 mM; Ethanol: >1 mg/ml; Hydrochloric Acid: <100 mM
form 
A solid
pka
11.71±0.70(Predicted)
color 
Off-white to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22474
Product name
AZD 3147
Packaging
500μg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
22474
Product name
AZD 3147
Packaging
1mg
Price
$55
Updated
2024/03/01
Cayman Chemical
Product number
22474
Product name
AZD 3147
Packaging
5mg
Price
$199
Updated
2024/03/01
Cayman Chemical
Product number
22474
Product name
AZD 3147
Packaging
10mg
Price
$275
Updated
2024/03/01
Tocris
Product number
5615
Product name
AZD3147
Purity
≥98%(HPLC)
Packaging
10
Price
$259
Updated
2021/12/16
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AZD3147 Chemical Properties,Usage,Production

Uses

AZD3147 is a selective dual inhibitor of mTORC1 and mTORC2 with physiochemical and pharmacokinectic properties suitable for clinical applications.

in vivo

The pharmacokinetic parameters of AZD3147[1].

ParameterMouseDog
CL (mL/min/kg)7816
Vss (L/kg)2.32.2
t1/2(h)0.91.9
F%6173

IC 50

mTORC1; mTORC2

AZD3147 Preparation Products And Raw materials

Raw materials

Preparation Products

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AZD3147 Suppliers

China 37 United Kingdom 1 United States 6 Global 44
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16077
Advantage
64
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4768
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Angel Pharmatech, Ltd.
Tel
17317130613
Fax
QQ3358272972
Email
3358272972@qq.com
Country
China
ProdList
3277
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30229
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Chunchuang (Wuhan) Technology Co., Ltd
Tel
15727060112
Email
yutianchun2007@126.com
Country
China
ProdList
9814
Advantage
58
Wuhan Shanhai Zhihe Biotechnology Co., Ltd.
Tel
17771424646
Email
shoubull@126.com
Country
China
ProdList
957
Advantage
58

1101810-02-9, AZD3147Related Search:


  • AZD3147
  • 1-[4-[4-(1-cyclopropylsulfonylcyclopropyl)-6-[(3S)-3-methylmorpholin-4-yl]pyrimidin-2-yl]phenyl]-3-(2-hydroxyethyl)thiourea
  • N-[4-[4-[1-(Cyclopropylsulfonyl)cyclopropyl]-6-[(3S)-3-methyl-4-morpholinyl]-2-pyrimidinyl]phenyl]-N'-(2-hydroxyethyl)thiourea
  • Thiourea, N-[4-[4-[1-(cyclopropylsulfonyl)cyclopropyl]-6-[(3S)-3-methyl-4-morpholinyl]-2-pyrimidinyl]phenyl]-N'-(2-hydroxyethyl)-
  • (S)-1-(4-(4-(1-(cyclopropylsulfonyl)cyclopropyl)-6-(3-methylmorpholino)pyrimidin-2-yl)phenyl)-3-(2-hydroxyethyl)thiourea
  • N-[4-[4-[1-(cyclopropylsulfonyl)cyclopropyl]-6-[(3S)-3-methyl-4-morpholinyl]-2-pyrimidinyl]phenyl]-N'-(2-hydroxyethyl)-thiourea
  • AZD 3147, 10 mM in DMSO
  • AZ-12600000
  • (S)-1-(4-(4-(1-(Cyclopropylsulfonyl)cyclopropyl)-6-(3-methylmorpholin-4-yl)-pyrimidin-2-yl)phenyl)-3-(2-hydroxyethyl)thiourea
  • 1101810-02-9