5'-O-Phosphorylguanylyl-(3'-5')-guanosine

Product Name: 5'-O-Phosphorylguanylyl-(3'-5')-guanosine
CAS No.: 33008-99-0
Chemical Name: 5'-O-Phosphorylguanylyl-(3'-5')-guanosine
Synonyms: pGpG;5'-Phosphoguanylyl-(3',5')-guanosine;5'-Phosphoguanylyl-(3'->5')-guanosine;5'-O-Phosphorylguanylyl-(3'-5')-guanosine;Guanosine, 5'-O-phosphonoguanylyl-(3'→5')-
CBNumber: CB63140866
Molecular Formula: C20H26N10O15P2
Formula Weight: 708.43
MOL File: 33008-99-0.mol

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5'-O-Phosphorylguanylyl-(3'-5')-guanosine Property

Density: 2.60±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
pka: 1.37±0.50(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: NP46568
Product name: 5'-Phosphoguanylyl-(3'->5')-guanosine
Packaging: 250ug
Price: $625
Updated: 2021/12/16

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5'-O-Phosphorylguanylyl-(3'-5')-guanosine Chemical Properties,Usage,Production

Biological Activity

5’-Phosphoguanylyl-(3’,5’)-guanosine (pGpG) is an intermediate molecule produced by the pathway for enzymatic cyclic diguanylate (c-di-GMP) degradation. 5’-Phosphoguanylyl-(3’,5’)-guanosine can be used to detect the metabolism of nucleic acids[1][2]. 5’-Phosphoguanylyl-(3’,5’)-guanosine reduces the rate of c-di-GMP degradation in cell lysates and inhibits the activity of EAL-dependent PDEs (PA2133, PvrR, and purified recombinant RocR) from P. aeruginosa[2].

References

[1]. Nesbitt NM, et, al. Modification of a bi-functional diguanylate cyclase-phosphodiesterase to efficiently produce cyclic diguanylate monophosphate. Biotechnol Rep (Amst). 2015 May 5;7:30-37. [2]. Cohen D, et, al. Oligoribonuclease is a central feature of cyclic diguanylate signaling in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):11359-64.

5'-O-Phosphorylguanylyl-(3'-5')-guanosine Preparation Products And Raw materials

Raw materials

Preparation Products

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5'-O-Phosphorylguanylyl-(3'-5')-guanosine Suppliers

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33008-99-0, 5'-O-Phosphorylguanylyl-(3'-5')-guanosineRelated Search:

5'-O-Phosphorylguanylyl-(3'-5')-guanosine

pGpG

5'-Phosphoguanylyl-(3'->5')-guanosine

Guanosine, 5'-O-phosphonoguanylyl-(3'→5')-

5'-Phosphoguanylyl-(3',5')-guanosine

33008-99-0

C20H26N10O15P2xNa