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PKCζ Pseudosubstrate Inhibitor

Product Name
PKCζ Pseudosubstrate Inhibitor
CAS No.
799764-07-1
Chemical Name
PKCζ Pseudosubstrate Inhibitor
Synonyms
Pseudosubstrate Inhibitor;PKCζ Pseudosubstrate Inhibitor;PKC.zeta. Pseudosubstrate Inhibitor;PKCζ Pseudosubstrate Inhibitor (Protein Kinase Cζ Pseudosubstrate Inhibitor);L-Leucine, L-seryl-L-isoleucyl-L-tyrosyl-L-arginyl-L-arginylglycyl-L-alanyl-L-arginyl-L-arginyl-L-tryptophyl-L-arginyl-L-lysyl-
CBNumber
CB63152717
Molecular Formula
C76H128N30O16
Formula Weight
1718.02
MOL File
799764-07-1.mol
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PKCζ Pseudosubstrate Inhibitor Property

Density 
1.48±0.1 g/cm3(Predicted)
solubility 
DMF: 20 mg/ml; DMSO: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
form 
A crystalline solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
17482
Product name
PKCζ Pseudosubstrate Inhibitor
Purity
≥95%
Packaging
500μg
Price
$96
Updated
2024/03/01
Cayman Chemical
Product number
17482
Product name
PKCζ Pseudosubstrate Inhibitor
Purity
≥95%
Packaging
1mg
Price
$182
Updated
2024/03/01
Cayman Chemical
Product number
17482
Product name
PKCζ Pseudosubstrate Inhibitor
Purity
≥95%
Packaging
5mg
Price
$758
Updated
2024/03/01
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PKCζ Pseudosubstrate Inhibitor Chemical Properties,Usage,Production

Description

The atypical protein kinase C isoform, PKCζ, is critical for mediating mitogenic signal transduction, cell survival, and some of the physiological actions of insulin.1 PKCζ pseudosubstrate inhibitor is a synthetic peptide that corresponds to a pseudosubstrate domain of this PKC isoform.2 It selectively, reversibly, and substrate-competitively inhibits PKCζ activity and, thus, is used to delineate the signaling functions of PKCζ.3,4,5

References

1. Toker, A. Signaling through protein kinase C Front. Biosci. 3,d1134-d1147(1998).
2. Eichholtz, T., de Bont, D.B.A., de Widt, J., et al. A myristoylated pseudosubstrate peptide, a novel protein kinase C inhibitor J. Biol. Chem. 268(3),1982-1986(1993).
3. Lee, A.W. The role of atypical protein kinase C in CSF-1-dependent Erk activation and proliferation in myeloid progenitors and macrophages PLoS One 6(10),e25580(2011).
4. Dang, P.M.C., Fontayne, A., Hakim, J., et al. Protein kinase C ζ phosphorylates a subset of selective sites of the NADPH oxidase component p47phox and participates in formyl peptide-mediated neutrophil respiratory burst J. Immunol. 166,1206-1213(2001).
5. Standaert, M.L., Galloway, L., Karnam, P., et al. Protein kinase C-ζ as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport J. Biol. Chem. 272(48),30075-30082(1997).

PKCζ Pseudosubstrate Inhibitor Preparation Products And Raw materials

Raw materials

Preparation Products

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PKCζ Pseudosubstrate Inhibitor Suppliers

Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6870
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11289
Advantage
58
JiangSu Star Science Co.,Ltd
Tel
400-605-7200 17312445705
Email
sales022@b2star.com
Country
China
ProdList
3764
Advantage
58
Shanghai Maclean Biochemical Technology Co., LTD
Tel
021-50706066 15221275939
Email
shenlinxing@macklin.cn
Country
China
ProdList
29803
Advantage
58
Shanghai HongTide Biotechnology Co.,Ltd.
Tel
19961912513
Email
sales@hongtide.com
Country
China
ProdList
4577
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
8740
Advantage
58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.com
Country
China
ProdList
24246
Advantage
58

799764-07-1, PKCζ Pseudosubstrate InhibitorRelated Search:


  • PKCζ Pseudosubstrate Inhibitor
  • PKC.zeta. Pseudosubstrate Inhibitor
  • Pseudosubstrate Inhibitor
  • PKCζ Pseudosubstrate Inhibitor (Protein Kinase Cζ Pseudosubstrate Inhibitor)
  • L-Leucine, L-seryl-L-isoleucyl-L-tyrosyl-L-arginyl-L-arginylglycyl-L-alanyl-L-arginyl-L-arginyl-L-tryptophyl-L-arginyl-L-lysyl-
  • 799764-07-1