2-methylsulfinyl-4-methyl-6-[(3-methoxyphenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinone

Product Name: 2-methylsulfinyl-4-methyl-6-[(3-methoxyphenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinone
CAS No.: 1221186-52-2
Chemical Name: 2-methylsulfinyl-4-methyl-6-[(3-methoxyphenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinone
Synonyms: ML 202;6-[(3-Methoxyphenyl)methyl]-4-methyl-2-methylsulfinylthieno[3,4]pyrrolo[1,3-d]pyridazin-5-one;2-methylsulfinyl-4-methyl-6-[(3-methoxyphenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinone;5H-Thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one, 4,6-dihydro-6-[(3-methoxyphenyl)methyl]-4-methyl-2-(methylsulfinyl)-
CBNumber: CB63160170
Molecular Formula: C18H17N3O3S2
Formula Weight: 387.48
MOL File: 1221186-52-2.mol

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2-methylsulfinyl-4-methyl-6-[(3-methoxyphenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinone Property

Boiling point:: 673.0±65.0 °C(Predicted)
Density: 1.49±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
pka: -1.00±0.20(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 37326
Product name: ML-202
Purity: ≥98%
Packaging: 1mg
Price: $42
Updated: 2026/04/30

Cayman Chemical

Product number: 37326
Product name: ML-202
Purity: ≥98%
Packaging: 5mg
Price: $200
Updated: 2026/04/30

Cayman Chemical

Product number: 37326
Product name: ML-202
Purity: ≥98%
Packaging: 10mg
Price: $377
Updated: 2026/04/30

Cayman Chemical

Product number: 37326
Product name: ML-202
Purity: ≥98%
Packaging: 25mg
Price: $836
Updated: 2026/04/30

Usbiological

Product number: 255851
Product name: ML 202
Packaging: 10mg
Price: $480
Updated: 2021/12/16

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2-methylsulfinyl-4-methyl-6-[(3-methoxyphenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinone Chemical Properties,Usage,Production

Uses

ML202 is a highly specific allosteric activator of human pyruvate kinase M2 (hPK-M2), which can affect the cooperativity of phosphoenolpyruvate (PEP) binding, while adenosine diphosphate (ADP) binding almost no effect[1].

Definition

ChEBI: 6-[(3-methoxyphenyl)methyl]-4-methyl-2-methylsulfinyl-5-thieno[3,4]pyrrolo[1,3-d]pyridazinone is an organosulfur heterocyclic compound, an organonitrogen heterocyclic compound and an organic heterobicyclic compound.

References

[1] Matthew B Boxer, et al. Identification of activators for the M2 isoform of human pyruvate kinase Version 3. 2009 Sep 1 [updated 2011 Mar 3]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID:21735594

2-methylsulfinyl-4-methyl-6-[(3-methoxyphenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinone Preparation Products And Raw materials

Raw materials

Preparation Products

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2-methylsulfinyl-4-methyl-6-[(3-methoxyphenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinone Suppliers

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1221186-52-2, 2-methylsulfinyl-4-methyl-6-[(3-methoxyphenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinoneRelated Search:

2-methylsulfinyl-4-methyl-6-[(3-methoxyphenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinone

ML 202

5H-Thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one, 4,6-dihydro-6-[(3-methoxyphenyl)methyl]-4-methyl-2-(methylsulfinyl)-

6-[(3-Methoxyphenyl)methyl]-4-methyl-2-methylsulfinylthieno[3,4]pyrrolo[1,3-d]pyridazin-5-one

1221186-52-2