Mal-PEG4-Glu(TFP ester)-NH-m-PEG24

Product Name: Mal-PEG4-Glu(TFP ester)-NH-m-PEG24
CAS No.: 2408741-87-5
Chemical Name: Mal-PEG4-Glu(TFP ester)-NH-m-PEG24
Synonyms: Mal-PEG4-Glu(TFP ester)-NH-m-PEG24;MAL-dPEG??-Glu(TFP ester)-NH-m-dPEG???;9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78-Tetracosaoxa-6-azanonaheptacontanoic acid, 4-[[19-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1,17-dioxo-4,7,10,13-tetraoxa-16-azanonadec-1-yl]amino]-5-oxo-, 2,3,5,6-tetrafluorophenyl ester, (4S)-
CBNumber: CB63162987
Molecular Formula: C78H134F4N4O35
Formula Weight: 1763.9
MOL File: 2408741-87-5.mol

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Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 Property

Boiling point:: 1305.2±65.0 °C(Predicted)
Density: 1.198±0.06 g/cm3(Predicted)
pka: 13.98±0.46(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

dPEG

Product number: 11581
Product name: MAL-dPEG®₄-Glu(TFPester)-NH-m-dPEG®₂₄
Packaging: 50mg
Price: $565
Updated: 2021/12/16

BroadPharm

Product number: BP-22754
Product name: Mal-PEG4-Glu(TFPester)-NH-m-PEG24
Purity: 98%
Packaging: 50mg
Price: $670
Updated: 2021/12/16

BroadPharm

Product number: BP-22754
Product name: Mal-PEG4-Glu(TFPester)-NH-m-PEG24
Purity: 98%
Packaging: 100mg
Price: $890
Updated: 2021/12/16

BroadPharm

Product number: BP-22754
Product name: Mal-PEG4-Glu(TFPester)-NH-m-PEG24
Purity: 98%
Packaging: 250mg
Price: $1280
Updated: 2021/12/16

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Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 Chemical Properties,Usage,Production

Biological Activity

Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 Preparation Products And Raw materials

Raw materials

Preparation Products

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Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 Suppliers

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2408741-87-5, Mal-PEG4-Glu(TFP ester)-NH-m-PEG24Related Search:

Mal-PEG4-Glu(TFP ester)-NH-m-PEG24

MAL-dPEG??-Glu(TFP ester)-NH-m-dPEG???

9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78-Tetracosaoxa-6-azanonaheptacontanoic acid, 4-[[19-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1,17-dioxo-4,7,10,13-tetraoxa-16-azanonadec-1-yl]amino]-5-oxo-, 2,3,5,6-tetrafluorophenyl ester, (4S)-

2408741-87-5

C78H134F4N4O35