ChemicalBook > CAS DataBase List > Mal-PEG4-Glu(TFP ester)-NH-m-PEG24
Mal-PEG4-Glu(TFP ester)-NH-m-PEG24
- Product Name
- Mal-PEG4-Glu(TFP ester)-NH-m-PEG24
- CAS No.
- 2408741-87-5
- Chemical Name
- Mal-PEG4-Glu(TFP ester)-NH-m-PEG24
- Synonyms
- Mal-PEG4-Glu(TFP ester)-NH-m-PEG24;MAL-dPEG??-Glu(TFP ester)-NH-m-dPEG???;9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78-Tetracosaoxa-6-azanonaheptacontanoic acid, 4-[[19-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1,17-dioxo-4,7,10,13-tetraoxa-16-azanonadec-1-yl]amino]-5-oxo-, 2,3,5,6-tetrafluorophenyl ester, (4S)-
- CBNumber
- CB63162987
- Molecular Formula
- C78H134F4N4O35
- Formula Weight
- 1763.9
- MOL File
- 2408741-87-5.mol
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Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 Property
- Boiling point:
- 1305.2±65.0 °C(Predicted)
- Density
- 1.198±0.06 g/cm3(Predicted)
- pka
- 13.98±0.46(Predicted)
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N-Bromosuccinimide Price
dPEG
- Product number
- 11581
- Product name
- MAL-dPEG®₄-Glu(TFPester)-NH-m-dPEG®₂₄
- Packaging
- 50mg
- Price
- $565
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-22754
- Product name
- Mal-PEG4-Glu(TFPester)-NH-m-PEG24
- Purity
- 98%
- Packaging
- 50mg
- Price
- $670
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-22754
- Product name
- Mal-PEG4-Glu(TFPester)-NH-m-PEG24
- Purity
- 98%
- Packaging
- 100mg
- Price
- $890
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-22754
- Product name
- Mal-PEG4-Glu(TFPester)-NH-m-PEG24
- Purity
- 98%
- Packaging
- 250mg
- Price
- $1280
- Updated
- 2021/12/16
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Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 Chemical Properties,Usage,Production
Biological Activity
Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 Preparation Products And Raw materials
Raw materials
Preparation Products
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Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 Suppliers
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