ChemicalBook > CAS DataBase List > Mal-PEG8-t-butyl ester

Mal-PEG8-t-butyl ester

Product Name
Mal-PEG8-t-butyl ester
CAS No.
2055048-43-4
Chemical Name
Mal-PEG8-t-butyl ester
Synonyms
Mal-PEG8-Boc;Mal-PEG8-COOtBu;Mal-PEG8-CH2CH2COOtBu;Mal-PEG8-t-butyl ester;tert-butyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate;4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 1,1-dimethylethyl ester;Mal-PEG8-CH2CH2COOtBu/4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 1,1-dimethylethyl ester
CBNumber
CB63162992
Molecular Formula
C27H47NO12
Formula Weight
577.66
MOL File
2055048-43-4.mol
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Mal-PEG8-t-butyl ester Property

Boiling point:
625.7±55.0 °C(Predicted)
Density 
1.144±0.06 g/cm3(Predicted)
storage temp. 
-20°C, stored under nitrogen
solubility 
Soluble in Water, DMSO, DMF, DCM
pka
-2.34±0.20(Predicted)
form 
Oil
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23335
Product name
Mal-PEG8-t-butylester
Purity
98%
Packaging
100mg
Price
$260
Updated
2021/12/16
BroadPharm
Product number
BP-23335
Product name
Mal-PEG8-t-butylester
Purity
98%
Packaging
250mg
Price
$480
Updated
2021/12/16
Acrotein
Product number
B-1566
Product name
Mal-PEG8-CH2CH2COOtBu
Purity
97%
Packaging
0.25g
Price
$220
Updated
2021/12/16
Acrotein
Product number
B-1566
Product name
Mal-PEG8-CH2CH2COOtBu
Purity
97%
Packaging
0.5g
Price
$330
Updated
2021/12/16
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Mal-PEG8-t-butyl ester Chemical Properties,Usage,Production

Description

Mal-PEG8-t-butyl ester is a PEG linker containing a maleimide group and a t-butyl ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Uses

Mal-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Mal-PEG8-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Mal-PEG8-t-butyl ester Suppliers

Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28772
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58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
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58
Alpha Biopharmaceuticals Co., Ltd
Tel
0411-39042497
Fax
0411-39042693
Email
sales@alphabiopharm.com
Country
China
ProdList
1951
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58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32467
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58
Nextpeptide Inc
Tel
+86-0571-81612335 +8613336028439
Email
sales@nextpeptide.com
Country
China
ProdList
19908
Advantage
58
Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
Tel
13892832556
Email
2440688701@qq.com
Country
China
ProdList
1995
Advantage
58
Xiamen Sinopeg Biotech Co., Ltd.
Tel
400-9189898 17359873007
Email
sales@sinopeg.com
Country
China
ProdList
1000
Advantage
58
Block Chemical Technology (Shanghai) Co., LTD
Tel
021-20432219 13918097649
Fax
QQ79021576
Email
li_jinfei@acblock-lab.com
Country
China
ProdList
9683
Advantage
58
Taizhou Nanfeng Pharmaceutical Research Institute
Tel
nanfengpharma@126.co 18616377689
Email
nanfengpharma@126.com
Country
China
ProdList
20009
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
54995
Advantage
58
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View Lastest Price from Mal-PEG8-t-butyl ester manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.
Product
MAL-PEG8-COOtBu 2055048-43-4
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle, 10g/bottle, 100g/bottle
Release date
2026-02-06
Xian confluore Biological Technology Co., Ltd.
Product
Mal-PEG8-COOtBu 2055048-43-4
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-27

2055048-43-4, Mal-PEG8-t-butyl esterRelated Search:


  • Mal-PEG8-t-butyl ester
  • Mal-PEG8-CH2CH2COOtBu
  • Mal-PEG8-COOtBu
  • Mal-PEG8-Boc
  • 4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 1,1-dimethylethyl ester
  • Mal-PEG8-CH2CH2COOtBu/4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 1,1-dimethylethyl ester
  • tert-butyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate
  • 2055048-43-4
  • C27H47NO12