Mal-PEG8-t-butyl ester

Product Name: Mal-PEG8-t-butyl ester
CAS No.: 2055048-43-4
Chemical Name: Mal-PEG8-t-butyl ester
Synonyms: Mal-PEG8-Boc;Mal-PEG8-COOtBu;Mal-PEG8-CH2CH2COOtBu;Mal-PEG8-t-butyl ester;tert-butyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate;4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 1,1-dimethylethyl ester;Mal-PEG8-CH2CH2COOtBu/4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 1,1-dimethylethyl ester
CBNumber: CB63162992
Molecular Formula: C27H47NO12
Formula Weight: 577.66
MOL File: 2055048-43-4.mol

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Mal-PEG8-t-butyl ester Property

Boiling point:: 625.7±55.0 °C(Predicted)
Density: 1.144±0.06 g/cm3(Predicted)
storage temp.: -20°C, stored under nitrogen
solubility: Soluble in Water, DMSO, DMF, DCM
pka: -2.34±0.20(Predicted)
form: Oil
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23335
Product name: Mal-PEG8-t-butylester
Purity: 98%
Packaging: 100mg
Price: $260
Updated: 2021/12/16

BroadPharm

Product number: BP-23335
Product name: Mal-PEG8-t-butylester
Purity: 98%
Packaging: 250mg
Price: $480
Updated: 2021/12/16

Acrotein

Product number: B-1566
Product name: Mal-PEG8-CH2CH2COOtBu
Purity: 97%
Packaging: 0.25g
Price: $220
Updated: 2021/12/16

Acrotein

Product number: B-1566
Product name: Mal-PEG8-CH2CH2COOtBu
Purity: 97%
Packaging: 0.5g
Price: $330
Updated: 2021/12/16

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Mal-PEG8-t-butyl ester Chemical Properties,Usage,Production

Description

Mal-PEG8-t-butyl ester is a PEG linker containing a maleimide group and a t-butyl ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Uses

Mal-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Mal-PEG8-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Mal-PEG8-t-butyl ester Suppliers

China 24 United States 2 Global 26

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 52923
Advantage: 58

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View Lastest Price from Mal-PEG8-t-butyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Mal-PEG8-COOtBu 2055048-43-4
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-27

2055048-43-4, Mal-PEG8-t-butyl esterRelated Search:

Mal-PEG8-OH Maleimido-mono-amide-NOTA Mal-PEG8-acid Mal-PEG20K-OMe Maleimide-SS-DBCO MaleiMido-Mono-aMide-DTPA 1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, 10-[2-[[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]amino]-2-oxoethyl]-, 1,4,7-tris(1,1-dimethylethyl) ester Mal-PEG8-NHS ester Mal-SS-NHS Mal-PEG8-Mal Mal-PEG10K-OMe

Mal-PEG8-t-butyl ester

Mal-PEG8-CH2CH2COOtBu

Mal-PEG8-COOtBu

Mal-PEG8-Boc

4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 1,1-dimethylethyl ester

Mal-PEG8-CH2CH2COOtBu/4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 1,1-dimethylethyl ester

tert-butyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate

2055048-43-4

C27H47NO12