4E2RCat

Product Name: 4E2RCat
CAS No.: 432499-63-3
Chemical Name: 4E2RCat
Synonyms: 4E2RCat;4E2RCat, 10 mM in DMSO;Eukaryotic Initiation Factor;5-(5-((3-benzyl-4-oxo-2-thiazolidinyl)methyl)furan-2-yl)-2-chlorobenzoic acid;5-(5-((3-Benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)-2-chlorobenzoic acid;4E-2RCat,Virus Protease,4E2RCat,Inhibitor,inhibit,Autophagy,Eukaryotic Initiation Factor (eIF);5-(5-((3-Benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)-2-chlorobenzoic acid[4E2RCat;Benzoic acid, 2-chloro-5-[5-[[4-oxo-3-(phenylmethyl)-2-thioxo-5-thiazolidinylidene]methyl]-2-furanyl]-
CBNumber: CB63167593
Molecular Formula: C22H14ClNO4S2
Formula Weight: 455.93
MOL File: 432499-63-3.mol

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4E2RCat Property

Boiling point:: 659.0±65.0 °C(Predicted)
Density: 1.56±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 15.5 mg/mL (34.00 mM)
form: Solid
pka: 2.72±0.25(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-6204
Product name: 4E2RCat
Purity: >98.0%
Packaging: 1mg
Price: $132
Updated: 2021/12/16

ChemScene

Product number: CS-6204
Product name: 4E2RCat
Purity: >98.0%
Packaging: 5mg
Price: $396
Updated: 2021/12/16

ChemScene

Product number: CS-6204
Product name: 4E2RCat
Purity: >98.0%
Packaging: 10mg
Price: $600
Updated: 2021/12/16

ChemScene

Product number: CS-6204
Product name: 4E2RCat
Purity: >98.0%
Packaging: 50mg
Price: $1800
Updated: 2021/12/16

ChemScene

Product number: CS-6204
Product name: 4E2RCat
Purity: >98.0%
Packaging: 100mg
Price: $2520
Updated: 2021/12/16

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4E2RCat Chemical Properties,Usage,Production

Uses

4E2RCat is an inhibitor of eIF4E-eIF4G interaction with an IC50 of 13.5 μM.

in vivo

4E2RCat inhibits protein synthesis in vivo and it is not a consequence of increased cell death^[1].

IC 50

eIF4

References

[1] Cencic R, et al. Blocking eIF4E-eIF4G interaction as a strategy to impair coronavirus replication. J Virol. 2011 Jul;85(13):6381-9. DOI:10.1128/JVI.00078-11

4E2RCat Preparation Products And Raw materials

Raw materials

Preparation Products

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4E2RCat Suppliers

China 34 United States 4 Global 38

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 9431
Advantage: 55

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 9543
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32470
Advantage: 58

Henan Weituxi Chemical Technology Co., Ltd.

Tel: 0371-63284658 18135795563
Fax: QQ:2885349392
Email: 3905209149@qq.com
Country: China
ProdList: 9912
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Shanghai Dongyang Biotechnology Co., Ltd.

Tel: 0512-0512-13601744364 13601744364
Email: chemsharker@126.com
Country: China
ProdList: 1073
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Shanghai hongqu biomedical technology co. LTD

Tel: 88888888888
Email: hongquchem@qq.com
Country: China
ProdList: 5132
Advantage: 58

432499-63-3, 4E2RCatRelated Search:

4E2RCat

Benzoic acid, 2-chloro-5-[5-[[4-oxo-3-(phenylmethyl)-2-thioxo-5-thiazolidinylidene]methyl]-2-furanyl]-

Eukaryotic Initiation Factor

5-(5-((3-Benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)-2-chlorobenzoic acid

5-(5-((3-Benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)-2-chlorobenzoic acid[4E2RCat

4E-2RCat,Virus Protease,4E2RCat,Inhibitor,inhibit,Autophagy,Eukaryotic Initiation Factor (eIF)

4E2RCat, 10 mM in DMSO

5-(5-((3-benzyl-4-oxo-2-thiazolidinyl)methyl)furan-2-yl)-2-chlorobenzoic acid

432499-63-3

C22H14ClNO4S2