GSK682753A

Product Name: GSK682753A
CAS No.: 1334294-76-6
Chemical Name: GSK682753A
Synonyms: GSK682753A;GSK-682753A,GSK682753A;EBI2 inhibitor GS682753A;(E)-8-(3-(4-Chlorophenyl)acryloyl)-3-(3,4-dichlorobenzyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one;(E)-8-(3-(4-Chlorophenyl)acryloyl)-3-(3,4-dichlorobenzyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one , GSK682753A;1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 8-[(2E)-3-(4-chlorophenyl)-1-oxo-2-propen-1-yl]-3-[(3,4-dichlorophenyl)methyl]-
CBNumber: CB63167614
Molecular Formula: C23H21Cl3N2O3
Formula Weight: 479.78
MOL File: 1334294-76-6.mol

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GSK682753A Property

Boiling point:: 731.8±60.0 °C(Predicted)
Density: 1.44±0.1 g/cm3(Predicted)
storage temp.: 4°C, protect from light
solubility: DMSO : ≥ 27 mg/mL (56.28 mM)
form: Solid
pka: -0.50±0.20(Predicted)
color: White to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-6260
Product name: GSK682753A
Purity: 99.84%
Packaging: 5mg
Price: $156
Updated: 2021/12/16

ChemScene

Product number: CS-6260
Product name: GSK682753A
Purity: 99.84%
Packaging: 10mg
Price: $264
Updated: 2021/12/16

ChemScene

Product number: CS-6260
Product name: GSK682753A
Purity: 99.84%
Packaging: 25mg
Price: $576
Updated: 2021/12/16

ChemScene

Product number: CS-6260
Product name: GSK682753A
Purity: 99.84%
Packaging: 50mg
Price: $996
Updated: 2021/12/16

ChemScene

Product number: CS-6260
Product name: GSK682753A
Purity: 99.84%
Packaging: 100mg
Price: $1680
Updated: 2021/12/16

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GSK682753A Chemical Properties,Usage,Production

Uses

GSK682753A is a selective and highly potent inverse agonist of the epstein-barr virus-induced receptor 2 (EBI2) with an IC50 of 53.6 nM.

References

[1] Benned-Jensen T, et al. Ligand modulation of the Epstein-Barr virus-induced seven-transmembrane receptor EBI2: identification of a potent and efficacious inverse agonist. J Biol Chem. 2011 Aug 19;286(33):29292-302. DOI:10.1074/jbc.M110.196345

GSK682753A Preparation Products And Raw materials

Raw materials

Preparation Products

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GSK682753A Suppliers

China 25 United States 6 Global 31

Shanghai EFE Biological Technology Co., Ltd.

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Beijing Jin Ming Biotechnology Co., Ltd.

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1334294-76-6, GSK682753ARelated Search:

GSK682753A

EBI2 inhibitor GS682753A

1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 8-[(2E)-3-(4-chlorophenyl)-1-oxo-2-propen-1-yl]-3-[(3,4-dichlorophenyl)methyl]-

GSK-682753A,GSK682753A

(E)-8-(3-(4-Chlorophenyl)acryloyl)-3-(3,4-dichlorobenzyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one

(E)-8-(3-(4-Chlorophenyl)acryloyl)-3-(3,4-dichlorobenzyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one , GSK682753A

1334294-76-6