BMS 986158
- Product Name
- BMS 986158
- CAS No.
- 1800340-40-2
- Chemical Name
- BMS 986158
- Synonyms
- BMS 986158;BMS-986158 ,S9691;BMS-986158 (BMS986158);BMS-986158, 10 mM in DMSO;BMS-986158;BMS 986158;BMS986158;BMS 986158,Epigenetic Reader Domain,inhibit,BMS-986158,Inhibitor,BMS986158;(S)-2-(3-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-5-(phenyl(tetrahydro-2H-pyran-4-yl)methyl)-5H-pyrido[3,2-b]indol-7-yl)propan-2-ol;5H-Pyrido[3,2-b]indole-7-methanol, 3-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-α,α-dimethyl-5-[(S)-phenyl(tetrahydro-2H-pyran-4-yl)methyl]-
- CBNumber
- CB63170234
- Molecular Formula
- C30H33N5O2
- Formula Weight
- 495.63
- MOL File
- 1800340-40-2.mol
BMS 986158 Property
- Boiling point:
- 674.0±65.0 °C(Predicted)
- Density
- 1.28±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 50 mM
- form
- A solid
- pka
- 14.31±0.29(Predicted)
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 27789
- Product name
- BMS 986158
- Packaging
- 1mg
- Price
- $97
- Updated
- 2024/03/01
- Product number
- 27789
- Product name
- BMS 986158
- Packaging
- 25mg
- Price
- $1439
- Updated
- 2024/03/01
- Product number
- 27789
- Product name
- BMS 986158
- Packaging
- 5mg
- Price
- $385
- Updated
- 2024/03/01
- Product number
- 27789
- Product name
- BMS 986158
- Packaging
- 10mg
- Price
- $672
- Updated
- 2024/03/01
- Product number
- 2604EF
- Product name
- 2-[3-(3,5-Dimethyltriazol-4-yl)-5-[(S)-oxan-4-yl(phenyl)methyl]pyrido[3,2-b]indol-7-yl]propan-2-ol
- Packaging
- 25mg
- Price
- $1699
- Updated
- 2021/12/16
BMS 986158 Chemical Properties,Usage,Production
Uses
BMS-986158 is a potent BET inhibitor with IC50s of 6.6 and 5 nM in NCI-H211 small cell lung cancer (SCLC) cells and MDA-MB231 triple negative breast cancer (TNBC) cells, respectively[1].
References
[1] Yin M, et al. Potent BRD4 inhibitor suppresses cancer cell-macrophage interaction. Nat Commun. 2020 Apr 14;11(1):1833. DOI:10.1038/s41467-020-15290-0
BMS 986158 Preparation Products And Raw materials
Raw materials
Preparation Products
BMS 986158 Suppliers
- Tel
- 18149758185 18149758185;
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- Country
- China
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- 3505
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- +86-21-52996696
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- China
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- 021-65675885
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- China
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- 58
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- 086-0519-83990708 18915800124
- Fax
- 0519-83990708
- info@pbpharm.com
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- China
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- 010-50973130 18101056239
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- CDXH21@126.com
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- United States
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- +1-708-310-1919 +1-13798911105
- Fax
- 708-557-7486
- sales@invivochem.cn
- Country
- United States
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- Tel
- 86-571-88216897,88216896 13588875226
- Fax
- 86-571-88216895
- sales@hzclap.com
- Country
- CHINA
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View Lastest Price from BMS 986158 manufacturers
- Product
- BMS 986158 1800340-40-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-13