2,2'-DIHYDROXYCHALCONE

Product Name: 2,2'-DIHYDROXYCHALCONE
CAS No.: 15131-80-3
Chemical Name: 2,2'-DIHYDROXYCHALCONE
Synonyms: 2,2'-Dihydroxychalcone;2,2'-Dihydroxychalcone;2,2'-Dihydroxychalchone;2,2''-DIHYDROXYCHALCHONE;2,2''-Dihydroxy chalcone;trans-2,2'-dihydroxychalcone;1,3-bis(2-hydroxyphenyl)-2-propen-1-on;1,3-DI(2-HYDROXYPHENYL)PROP-2-EN-1-ONE;Chalcone, 2,2'-dihydroxy- (6ci,7ci,8ci);1,3-bis(2-hydroxyphenyl)-2-propen-1-one
CBNumber: CB6318442
Molecular Formula: C15H12O3
Formula Weight: 240.25
MOL File: 15131-80-3.mol

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2,2'-DIHYDROXYCHALCONE Property

Melting point:: 161-162°C
Boiling point:: 447.1±45.0 °C(Predicted)
Density: 1.286±0.06 g/cm3(Predicted)
pka: 7.72±0.30(Predicted)
form: solid

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Safety

RIDADR: UN 2811 6.1 / PGIII
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: IDF00045
Product name: 2,2′-Dihydroxychalcone
Purity: Aldrich
Packaging: 1g
Price: $179
Updated: 2025/07/31

TRC

Product number: D452863
Product name: 2,2''-Dihydroxychalcone
Packaging: 100mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD66599
Product name: 2,2'-Dihydroxychalcone
Packaging: 2g
Price: $75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD66599
Product name: 2,2'-Dihydroxychalcone
Packaging: 5G
Price: $125
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD66599
Product name: 2,2'-Dihydroxychalcone
Packaging: 10g
Price: $200
Updated: 2021/12/16

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2,2'-DIHYDROXYCHALCONE Chemical Properties,Usage,Production

Uses

2,2′-Dihydroxychalcone, a flavonoid, is a glutathione S-transferase (GST) inhibitor with an IC50 of 28.9 μM in human colon cancer cells. 2,2′-Dihydroxychalcone induces cell cycle arrest and apoptosis in prostate cancer cells. 2,2′-Dihydroxychalcone has anticancer and anti-inflammatory properties[1][2].

References

[1] Ahmed Q Haddad, et al. Antiproliferative mechanisms of the flavonoids 2,2'-dihydroxychalcone and fisetin in human prostate cancer cells. Nutr Cancer. 2010;62(5):668-81. DOI:10.1080/01635581003605524
[2] Kenneth Goh, et al. 2,2'-Dihydroxychalcone, a glutathione transferase inhibitor, sensitises human colon adenocarcinoma cells to chlorambucil and melphalan, but not to actinomycin D. Mol Med Rep. 2008 Jul-Aug;1(4):575-9. PMID:21479453

2,2'-DIHYDROXYCHALCONE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,2'-DIHYDROXYCHALCONE Suppliers

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15131-80-3, 2,2'-DIHYDROXYCHALCONERelated Search:

3,2'-DIHYDROXYFLAVONE DATISCETIN 2'-METHOXYFLAVONE MORIN 2'-HYDROXY-2,3-DIMETHOXYCHALCONE 3-HYDROXY-2'-METHOXYFLAVONE 2',4'-DIHYDROXYCHALCONE [(E)-2',4'-Dihydroxychalcone-4-yl]β-D-glucopyranoside 4,2'-DIHYDROXYCHALCONE,2',4-DIHYDROXYCHALCONE DHF 5,2'-DIMETHOXYFLAVONE 5-HYDROXY-2'-METHOXYFLAVONE 7,2'-DIMETHOXYFLAVONE 2'-HYDROXY-2-METHOXYCHALCONE 3,2'-DIMETHOXYFLAVONE 6,2'-DIMETHOXYFLAVONE 5,2'-DIHYDROXYFLAVONE 4,4'-Dihydroxychalcone, 4-Methyl ether

1,3-bis(2-hydroxyphenyl)-2-propen-1-on

1,3-bis(2-hydroxyphenyl)-2-propen-1-one

2’-hydroxy-3-(o-hydroxyphenyl)-acrylophenon

2-Propen-1-one, 1,3-bis(2-hydroxyphenyl)-

Acrylophenone, 2'-hydroxy-3-(o-hydroxyphenyl)-

Chalcone, 2,2'-dihydroxy- (6ci,7ci,8ci)

1,3-Bis-(2-hydroxyphenyl)prop-2-en-1-one

(E)-1,3-bis(2-hydroxyphenyl)prop-2-en-1-one

1,3-DI(2-HYDROXYPHENYL)PROP-2-EN-1-ONE

2,2''-DIHYDROXYCHALCHONE

trans-2,2'-dihydroxychalcone

2,2'-Dihydroxychalcone

2,2'-Dihydroxychalchone

2,2''-Dihydroxy chalcone

2,2'-Dihydroxychalcone

15131-80-3

Chalcones