ChemicalBook > CAS DataBase List > 7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin

7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin

Product Name
7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin
CAS No.
76877-33-3
Chemical Name
7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin
Synonyms
CPM;AURORA KA-6719;Anti-CPM antibody produced in rabbit;Recombinant Human CPM Protein, His Tag;Recombinant Mouse Cpm Protein, His Tag;7-Diethylamino-3-(4-maleimidophenyl)-4-methylcumarin;7-DIETHYLAMINO-3-(4-MALEIMIDOPHENYL)-4-METHYLCOUMARIN;7-DIETHYLAMINO-3-(4-MALEIMIODOPHENYL)-4-METHYLCOUMARIN;7-DIETHYLAMINO-3-(4'-MALEIMIDYLPHENYL)-4-METHYLCOUMARIN;7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin
CBNumber
CB6319454
Molecular Formula
C24H22N2O4
Formula Weight
402.44
MOL File
76877-33-3.mol
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7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin Property

Melting point:
220-223°C
Boiling point:
618.7±55.0 °C(Predicted)
Density 
1.302±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO: soluble
pka
3.28±0.20(Predicted)
form 
solid
color 
yellow
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Safety

WGK Germany 
3
10
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SAB4500438
Product name
Anti-CPM antibody produced in rabbit
Purity
affinity isolated antibody
Packaging
100μG
Price
$506
Updated
2024/03/01
Sigma-Aldrich
Product number
HPA002657
Product name
Anti-CPM antibody produced in rabbit
Purity
affinity isolated antibody, buffered aqueous glycerol solution
Packaging
100μL
Price
$580
Updated
2024/03/01
Sigma-Aldrich
Product number
C1484
Product name
7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin
Purity
≥95% (HPLC), solid
Packaging
25mg
Price
$417
Updated
2024/03/01
Sigma-Aldrich
Product number
96669
Product name
7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin
Purity
BioReagent, suitable for fluorescence, ≥90% (HPCE)
Packaging
10mg
Price
$201
Updated
2024/03/01
Sigma-Aldrich
Product number
HPA002657
Product name
Anti-CPM antibody produced in rabbit
Purity
affinity isolated antibody, buffered aqueous glycerol solution
Packaging
25μL
Price
$282
Updated
2023/06/20
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7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin Chemical Properties,Usage,Production

Description

7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin is a thiol-reactive fluorescent probe. It displays excitation/emission maxima of 387/468 nm, respectively, and fluorescence intensity increases when bound to cysteine residues.

Uses

(7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin)CPM is probably the most widely used blue fluorescent thiol-reactive dye. This maleimide derivative of coumarin is essentially nonfluorescent until it reacts with thiols, making it possible to quantify thiols without a separation step. CPM is a good energ

Uses

7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin is a thiol-reactive fluorescent probe. 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin (CPM) is a thiol-reactive fluorescent probe. CPM selectively forms Michael adducts in the presence of hyperreactive sulfhydryls. CPM has been used to monitor the release of thiols, quantitate thiol in microplate reactions, and to distinguish proliferating cancer cells by nucleolar protein staining. Dyes and metabolites.

7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin Preparation Products And Raw materials

Raw materials

Preparation Products

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7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin Suppliers

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76877-33-3, 7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarinRelated Search:


  • CPM
  • AURORA KA-6719
  • 7-DIETHYLAMINO-3-(4-MALEIMIDOPHENYL)-4-METHYLCOUMARIN
  • 7-DIETHYLAMINO-3-(4'-MALEIMIDYLPHENYL)-4-METHYLCOUMARIN
  • 7-DIETHYLAMINO-3-(4-MALEIMIODOPHENYL)-4-METHYLCOUMARIN
  • 1H-PYRROLE-2,5-DIONE, 1-(4-(7-(DIETHYLAMINO)-4-METHYL-2-OXO-2H-1-BENZOPYRAN-3-YL)PHENYL)-
  • 1-[4-(7-Diethylamino-4-methyl-2-oxo-2H-chromen-3-yl)-phenyl]-pyrrole-2,5-dione
  • 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcumarin
  • n-(4-(7-diethylamino-4-methylcoumarin-3-yl)phenyl)maleimide
  • CPM [7-DiethylaMino-3-(4'-MaleiMidylphenyl)-4-MethylcouMarin]
  • Anti-Carboxypeptidase M precursor antibody produced in rabbit
  • Anti-CPM antibody produced in rabbit
  • 1-[4-[7-(Diethylamino)-4-methyl-2-oxo-chromen-3-yl]phenyl]pyrrole-2,5-dione
  • Recombinant Human CPM Protein, His Tag
  • Recombinant Mouse Cpm Protein, His Tag
  • 1-(4-(7-(Diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)phenyl)-1H-pyrrole-2,5-dione
  • 7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin
  • 76877-33-3
  • C22H22IN2O4
  • C24H22N24
  • Fluorescent Labels
  • Fluorescent Probes, Labels, Particles and Stains
  • Other Fluorescent Labels
  • BioChemical
  • Biochemicals and Reagents
  • Coumarines