ChemicalBook > CAS DataBase List > PHM-27 (HUMAN)

PHM-27 (HUMAN)

Product Name: PHM-27 (HUMAN)
CAS No.: 87403-73-4
Chemical Name: PHM-27 (HUMAN)
Synonyms: phm-27;Human PHI;PHI HUMAN;PHM, HUMAN;PHI-27, human;PHM-27 (HUMAN);PHM 27 (human) TFA;PHM-27 (PHI, human);peptide histidine methionine;PEPTIDE HISTIDINE METHIONINE, HUMAN
CBNumber: CB6321709
Molecular Formula: C135H214N34O40S
Formula Weight: 2985.46
MOL File: 87403-73-4.mol

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PHM-27 (HUMAN) Property

Boiling point:: 2732.1±65.0 °C(Predicted)
Density: 1.303±0.06 g/cm3(Predicted)
storage temp.: -15°C
form: Solid
color: White to off-white
Sequence: {His}{Ala}{Asp}{Gly}{Val}{Phe}{Thr}{Ser}{Asp}{Phe}{Ser}{Lys}{Leu}{Leu}{Gly}{Gln}{Leu}{Ser}{Ala}{Lys}{Lys}{Tyr}{Leu}{Glu}{Ser}{Leu}{Met}-NH2

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 2080
Product name: PHM27(human)
Packaging: 1
Price: $224
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb372703
Product name: PHM-27
Purity: > 95%
Packaging: 1mg
Price: $620.5
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0009216
Product name: PHM-27/PHI-HUMAN
Purity: 95.00%
Packaging: 1MG
Price: $762.3
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb372703
Product name: PHM-27
Purity: > 95%
Packaging: 5mg
Price: $1319.2
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0009216
Product name: PHM-27/PHI-HUMAN
Purity: 95.00%
Packaging: 5MG
Price: $1331
Updated: 2021/12/16

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PHM-27 (HUMAN) Chemical Properties,Usage,Production

Uses

PHM-27 (human) is a human prepro-vasoactive intestinal polypeptide (27 amino acid). PHM-27 (human) is a potent the human calcitonin receptor agonist with an EC50 of 11 nM. PHM-27 (human) efficiently enhances glucose-induced insulin secretion from beta cells by an autocrine mechanism[1][2][3].

References

[1] N Itoh, et al. Human preprovasoactive intestinal polypeptide contains a novel PHI-27-like peptide, PHM-27. Nature. 1983 Aug 11-17;304(5926):547-9. DOI:10.1038/304547a0
[2] Jian-Nong Ma, et al. Discovery of novel peptide/receptor interactions: identification of PHM-27 as a potent agonist of the human calcitonin receptor. Biochem Pharmacol. 2004 Apr 1;67(7):1279-84. DOI:10.1016/j.bcp.2003.11.008
[3] I Kato, et al. Transgenic mice overexpressing human vasoactive intestinal peptide (VIP) gene in pancreatic beta cells. Evidence for improved glucose tolerance and enhanced insulin secretion by VIP and PHM-27 in vivo. J Biol Chem. 1994 Aug 19;269(33):21223 PMID:8063743

PHM-27 (HUMAN) Preparation Products And Raw materials

Raw materials

Preparation Products

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87403-73-4, PHM-27 (HUMAN)Related Search:

(Z)-2-Methoxyimino-2-(furyl-2-yl) acetic acid ammonium salt ([125I]-TYR)-PHM-27 (HUMAN) Vasoactive Intestinal Peptide, PHM-27 (human) ANTI-PHM-27 (HUMAN) PHM-27 (HUMAN)

PHM-27 (HUMAN)

PHM, HUMAN

PHI HUMAN

PEPTIDE HISTIDINE METHIONINE, HUMAN

HIS-ALA-ASP-GLY-VAL-PHE-THR-SER-ASP-PHE-SER-LYS-LEU-LEU-GLY-GLN-LEU-SER-ALA-LYS-LYS-TYR-LEU-GLU-SER-LEU-MET-NH2

H-HIS-ALA-ASP-GLY-VAL-PHE-THR-SER-ASP-PHE-SER-LYS-LEU-LEU-GLY-GLN-LEU-SER-ALA-LYS-LYS-TYR-LEU-GLU-SER-LEU-MET-NH2

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Human PHI

L-Methioninamide, L-histidyl-L-alanyl-L-α-aspartylglycyl-L-valyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-phenylalanyl-L-seryl-L-lysyl-L-leucyl-L-leucylglycyl-L-glutaminyl-L-leucyl-L-seryl-L-alanyl-L-lysyl-L-lysyl-L-tyrosyl-L-leucyl-L-α-glutamyl-L-seryl-L-leucyl-

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PHM 27 (human) TFA

87403-73-4

PHM