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1-(3-Chlorphenyl)piperazine

Product Name
1-(3-Chlorphenyl)piperazine
CAS No.
6640-24-0
Chemical Name
1-(3-Chlorphenyl)piperazine
Synonyms
MCPP;1-(3-CHLOROPHENYL)PIPERAZINE;CHLOROPHENYLPIPERAZINE;m-Chlorophenylpiperazine;NSC 49307;AKOS BBS-00003580;TIMTEC-BB SBB003579;RARECHEM AH CK 0071;1,3ChlorofenylPiperazine;3-chlorophenyl piperazine
CBNumber
CB6325545
Molecular Formula
C10H13ClN2
Formula Weight
196.68
MOL File
6640-24-0.mol
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1-(3-Chlorphenyl)piperazine Property

Melting point:
210-214°C
Boiling point:
105 °C
Density 
1.193
refractive index 
1,598-1,600
storage temp. 
-20°C Freezer, Under Inert Atmosphere
solubility 
Chloroform (Slightly), Methanol (Sparingly)
form 
Oil
pka
8.85±0.10(Predicted)
color 
Colourless to Orange
LogP
2.468
CAS DataBase Reference
6640-24-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39-36
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Hazard statements

H411Toxic to aquatic life with long lasting effects

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N-Bromosuccinimide Price

TRC
Product number
C379590
Product name
1-(3-Chlorophenyl)piperazine
Packaging
1g
Price
$240
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK287024
Product name
1-(3-Chlorophenyl)piperazine
Purity
98%
Packaging
5g
Price
$59
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK287024
Product name
1-(3-Chlorophenyl)piperazine
Purity
98%
Packaging
25g
Price
$219
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
8430
Product name
1-(3-Chlorophenyl)piperazine
Packaging
25mg
Price
$2000
Updated
2021/12/16
Abosyn
Product number
61-3144
Product name
1-(3-Chlorophenyl)piperazine
Purity
95%-98%
Packaging
1g
Price
$90
Updated
2021/12/16
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1-(3-Chlorphenyl)piperazine Chemical Properties,Usage,Production

Chemical Properties

clear colorless to light yellow oily liquid

Uses

It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone. The metabolite m-CPP is of significant interest because it has 5-HT2C agonistic and 5-HT2A antagonistic properties. It has also been suggested that m-CPP may contribute to the antidepressant efficacy of Trazodone.

Uses

It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone (1,2,3). The metabolite m-CPP is of significant interest because it has 5-HT2C agonistic and 5-HT2A antagonistic properties. It has also been suggested that m-CPP may contribute to the antidepressant efficacy of Trazodone.

Definition

ChEBI: A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.

Hazard

A poison.

1-(3-Chlorphenyl)piperazine Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(3-Chlorphenyl)piperazine Suppliers

6640-24-0, 1-(3-Chlorphenyl)piperazineRelated Search:


  • RARECHEM AH CK 0071
  • N-(3-CHLOROPHENYL)PIPERAZINE
  • TIMTEC-BB SBB003579
  • MCPP
  • 1-(3-CHLORPHENYL)-PIPERAZINE
  • 1-(3-CHLOROPHENYL)PIPERAZINE
  • 1-(3-Chlorophenyl)piperazine 97%
  • 1-(3-CHLOROPHENYL)PIPERAZINE (MCPP)
  • 3-chlorophenyl piperazine
  • AKOS BBS-00003580
  • 1-(3-CHLOROPHENYL)PIPERAZINE HBR
  • 1,3ChlorofenylPiperazine
  • 3-Chlorophenyl-1-Piperazine
  • CHLOROPHENYLPIPERAZINE
  • 4-(3-Chlorophenyl)piperazine
  • N-(m-Chlorophenyl)piperazine
  • NSC 49307
  • Piperazine, 1-(3-chlorophenyl)-
  • 1-(3-Chlorophenyl)piperazine ,98%
  • m-Chlorophenylpiperazine
  • 1-(3-Chlorophenyl)piperazine,95%
  • Piperazine, 1-(3-chlorophenyl)-, monohydrochloride
  • Piperazine, 1-(m-chlorophenyl)-, monohydrochloride
  • N-(3-Chlorophenyl) piperazine 1-(3-Chlorophenyl) piperazine
  • Metachlorophenyl Piprazine
  • 1-(3-CHLOROPHENYL) PIPERAZINE ( CPP )
  • 6640-24-0
  • 39512-50-01
  • 5-HT2c serotonin receptor agonist; metabolite of trazodone.
  • FOR TRAZODONE'S PRODUCTION
  • Various Metabolites and Impurities
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • PHARMACEUTICAL INTERMEDIATES
  • Piperidines, Piperidones, Piperazines
  • Piperaizine
  • API intermediates
  • Piperazines