RIBOFLAVINE TETRABUTYRATE
- Product Name
- RIBOFLAVINE TETRABUTYRATE
- CAS No.
- 752-56-7
- Chemical Name
- RIBOFLAVINE TETRABUTYRATE
- Synonyms
- hibon;Riboflavinebutyrate;Guaiacol Impurity 18;2,3,4,5-Tetrabutyrate;VITAMIN B2 TETRABUTYRATE;RIBOFLAVIN TETRABUTYRATE;RIBOFLAVINE TETRABUTYRATE;Riboflavin Tetrabutyrate >riboflavin,2’,3’,4’,5’-tetrabutyrate;riboflavin,2’,3’,4’,5’-tetrabutanoate
- CBNumber
- CB6326623
- Molecular Formula
- C33H44N4O10
- Formula Weight
- 656.72
- MOL File
- 752-56-7.mol
RIBOFLAVINE TETRABUTYRATE Property
- Melting point:
- 149 °C
- Density
- 1.250 g/cm3
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Sparingly)
- form
- Solid
- pka
- 9.83±0.70(Predicted)
- color
- Yellow
- Merck
- 14,8200
- InChIKey
- MJNIWUJSIGSWKK-FSGGQHMVSA-N
- SMILES
- CC1C(C)=CC2N=C3C(=NC(=O)NC3=O)N(C[C@@H](OC(=O)CCC)[C@@H](OC(=O)CCC)[C@@H](OC(=O)CCC)COC(=O)CCC)C=2C=1
Safety
- RTECS
- VJ1755000
- HS Code
- 2934.99.4400
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P233Keep container tightly closed.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304IF INHALED:
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P340Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362Take off contaminated clothing and wash before reuse.
P403Store in a well-ventilated place.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- R0055
- Product name
- Riboflavin Tetrabutyrate
- Purity
- >98.0%(HPLC)
- Packaging
- 5g
- Price
- $61
- Updated
- 2025/07/31
- Product number
- R0055
- Product name
- Riboflavin Tetrabutyrate
- Purity
- >98.0%(HPLC)
- Packaging
- 25g
- Price
- $199
- Updated
- 2025/07/31
- Product number
- R590698
- Product name
- RiboflavineTetrabutyrate
- Packaging
- 50mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- R590698
- Product name
- RiboflavineTetrabutyrate
- Packaging
- 100mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- CS-7761
- Product name
- Riboflavin Tetrabutyrate
- Purity
- 98.16%
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
RIBOFLAVINE TETRABUTYRATE Chemical Properties,Usage,Production
Uses
Riboflavin Tetrabutyrate is a lipophilic flavin derivative with antioxidative and lipid peroxide-removing activity.
Definition
ChEBI: Riboflavin butyrate is a flavin.
in vivo
Riboflavin Tetrabutyrate might improve the metabolism of lipids in patients suffering from atherosclerosis, diabetes, fatty liver and so on through the inhibition of lipid peroxide, resulting in the decrease of the elevated serum lipid[1]. Feeding of Riboflavin Tetrabutyrate results in an increase in the hepatic activity of 3-ketoacyl-CoA thiolase by 50% of the control level, while the activities of renal 3-ketoacyl-CoA thiolase and of hepatic and renal acyl-CoA synthetase and acyl-CoA dehydrogenase remain unaffected. The increase in hepatic 3-ketoacyl-CoA thiolase activity suggests that prolonged Riboflavin Tetrabutyrate administration results in an increased beta-oxidation of fatty acid in the liver [2].
References
[1] Tahara K, et al. Effect of riboflavin and riboflavin 2',3',4',5'-tetrabutyrate on rat liver microsomallipid peroxidation. J Nutr Sci Vitaminol (Tokyo). 1974;20(2):81-8. DOI:10.3177/jnsv.20.81
[2] Okuno E, et al. Effect of chronic administration of riboflavin 2',3',4',5'-tetrabutyrate on the hepatic enzymes of fatty acid oxidation in the rat. J Nutr Sci Vitaminol (Tokyo). 1983 Dec;29(6):637-42. DOI:10.3177/jnsv.29.637
[3] Yagi K, et al. Studies on fatty acid esters of flavins. VI. Incorporation of riboflavin part of riboflavin tetrabutyrate-2-14C into flavin nucleotides in the organs of rat. J Vitaminol (Kyoto). 1969 Jun 10;15(2):155-9. PMID:5347449
RIBOFLAVINE TETRABUTYRATE Preparation Products And Raw materials
Raw materials
Preparation Products
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