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RIBOFLAVINE TETRABUTYRATE

Product Name
RIBOFLAVINE TETRABUTYRATE
CAS No.
752-56-7
Chemical Name
RIBOFLAVINE TETRABUTYRATE
Synonyms
hibon;Riboflavinebutyrate;Guaiacol Impurity 18;2,3,4,5-Tetrabutyrate;VITAMIN B2 TETRABUTYRATE;RIBOFLAVIN TETRABUTYRATE;RIBOFLAVINE TETRABUTYRATE;Riboflavin Tetrabutyrate >riboflavin,2’,3’,4’,5’-tetrabutyrate;riboflavin,2’,3’,4’,5’-tetrabutanoate
CBNumber
CB6326623
Molecular Formula
C33H44N4O10
Formula Weight
656.72
MOL File
752-56-7.mol
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RIBOFLAVINE TETRABUTYRATE Property

Melting point:
149 °C
Density 
1.250 g/cm3
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Sparingly)
form 
Solid
pka
9.83±0.70(Predicted)
color 
Yellow
Merck 
14,8200
InChIKey
MJNIWUJSIGSWKK-FSGGQHMVSA-N
SMILES
CC1C(C)=CC2N=C3C(=NC(=O)NC3=O)N(C[C@@H](OC(=O)CCC)[C@@H](OC(=O)CCC)[C@@H](OC(=O)CCC)COC(=O)CCC)C=2C=1
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Safety

RTECS 
VJ1755000
HS Code 
2934.99.4400
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P233Keep container tightly closed.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304IF INHALED:

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P340Remove victim to fresh air and keep at rest in a position comfortable for breathing.

P362Take off contaminated clothing and wash before reuse.

P403Store in a well-ventilated place.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
R0055
Product name
Riboflavin Tetrabutyrate
Purity
>98.0%(HPLC)
Packaging
5g
Price
$61
Updated
2025/07/31
TCI Chemical
Product number
R0055
Product name
Riboflavin Tetrabutyrate
Purity
>98.0%(HPLC)
Packaging
25g
Price
$199
Updated
2025/07/31
TRC
Product number
R590698
Product name
RiboflavineTetrabutyrate
Packaging
50mg
Price
$50
Updated
2021/12/16
TRC
Product number
R590698
Product name
RiboflavineTetrabutyrate
Packaging
100mg
Price
$70
Updated
2021/12/16
ChemScene
Product number
CS-7761
Product name
Riboflavin Tetrabutyrate
Purity
98.16%
Packaging
100mg
Price
$60
Updated
2021/12/16
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RIBOFLAVINE TETRABUTYRATE Chemical Properties,Usage,Production

Uses

Riboflavin Tetrabutyrate is a lipophilic flavin derivative with antioxidative and lipid peroxide-removing activity.

Definition

ChEBI: Riboflavin butyrate is a flavin.

in vivo

Riboflavin Tetrabutyrate might improve the metabolism of lipids in patients suffering from atherosclerosis, diabetes, fatty liver and so on through the inhibition of lipid peroxide, resulting in the decrease of the elevated serum lipid[1]. Feeding of Riboflavin Tetrabutyrate results in an increase in the hepatic activity of 3-ketoacyl-CoA thiolase by 50% of the control level, while the activities of renal 3-ketoacyl-CoA thiolase and of hepatic and renal acyl-CoA synthetase and acyl-CoA dehydrogenase remain unaffected. The increase in hepatic 3-ketoacyl-CoA thiolase activity suggests that prolonged Riboflavin Tetrabutyrate administration results in an increased beta-oxidation of fatty acid in the liver [2].

References

[1] Tahara K, et al. Effect of riboflavin and riboflavin 2',3',4',5'-tetrabutyrate on rat liver microsomallipid peroxidation. J Nutr Sci Vitaminol (Tokyo). 1974;20(2):81-8. DOI:10.3177/jnsv.20.81
[2] Okuno E, et al. Effect of chronic administration of riboflavin 2',3',4',5'-tetrabutyrate on the hepatic enzymes of fatty acid oxidation in the rat. J Nutr Sci Vitaminol (Tokyo). 1983 Dec;29(6):637-42. DOI:10.3177/jnsv.29.637
[3] Yagi K, et al. Studies on fatty acid esters of flavins. VI. Incorporation of riboflavin part of riboflavin tetrabutyrate-2-14C into flavin nucleotides in the organs of rat. J Vitaminol (Kyoto). 1969 Jun 10;15(2):155-9. PMID:5347449

RIBOFLAVINE TETRABUTYRATE Preparation Products And Raw materials

Raw materials

Preparation Products

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RIBOFLAVINE TETRABUTYRATE Suppliers

Chongqing Daxin Pharmaceutical Co., Ltd.
Tel
86-21-61462981
Fax
+86 (23) 6751-9202
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liumd@fsspc.com
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China
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J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
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China
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40228
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TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
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Sales-CN@TCIchemicals.com
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China
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Energy Chemical
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021-021-58432009 400-005-6266
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021-58436166
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sales8178@energy-chemical.com
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China
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TOKYO CHEMICAL INDUSTRY CO., LTD.
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03-36680489
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03-3668-0520
Email
Sales-JP@TCIchemicals.com
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Japan
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9ding chemical ( Shanghai) Limited
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4009209199
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86-021-52271987
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sales@9dingchem.com
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China
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Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
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China
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71826
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9ding chemical ( Shanghai) Limited
Tel
021-021-52271985 17721149837
Fax
+86 (21) 52271987
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sales@9dingchem.com
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China
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19800
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Aikon International Limited
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025-58859352 18068836627
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
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752-56-7, RIBOFLAVINE TETRABUTYRATERelated Search:


  • RIBOFLAVINE TETRABUTYRATE
  • RIBOFLAVIN TETRABUTYRATE
  • VITAMIN B2 TETRABUTYRATE
  • hibon
  • riboflavin,2’,3’,4’,5’-tetrabutanoate
  • riboflavin,2’,3’,4’,5’-tetrabutyrate
  • Riboflavinebutyrate
  • [(2S,3S,4R)-3,4,5-tri(butanoyloxy)-1-(7,8-dimethyl-2,4-dioxo-benzo[g]pteridin-10-yl)pentan-2-yl] butanoate
  • [(2S,3S,4R)-3,4,5-tri(butanoyloxy)-1-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)pentan-2-yl] butanoate
  • butyric acid [(1S,2S,3R)-2,3,4-tributyryloxy-1-[(2,4-diketo-7,8-dimethyl-benzo[g]pteridin-10-yl)methyl]butyl] ester
  • 2,3,4,5-Tetrabutyrate
  • Riboflavin Tetrabutyrate &gt
  • inhibit,Inhibitor,Reactive Oxygen Species,Riboflavin Tetrabutyrate
  • Guaiacol Impurity 18
  • Riboflavin Tetrabutyrate, 10 mM in DMSO
  • 752-56-7
  • C33H44N4O10
  • C33H34N4O10
  • Biochemistry
  • Vitamins
  • Vitamins and derivatives