LRE1

Product Name: LRE1
CAS No.: 1252362-53-0
Chemical Name: LRE1
Synonyms: LRE1;LRE1 - RU-0204277;LRE1 >=98% (HPLC);LRE1, 10 mM in DMSO;2,4-Pyrimidinediamine, 6-chloro-N4-cyclopropyl-N4-(2-thienylmethyl)-;6-Chloro-N4-cyclopropyl-N4-(thiophen-2-ylmethyl)pyrimidine-2,4-diamine;6-Chloro-4-N-cyclopropyl-4-N-(thiophen-2-ylmethyl)pyrimidine-2,4-diamine
CBNumber: CB63309355
Molecular Formula: C12H13ClN4S
Formula Weight: 280.78
MOL File: 1252362-53-0.mol

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LRE1 Property

Boiling point:: 532.6±60.0 °C(Predicted)
Density: 1.496±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: 10mg/mL, clear
pka: 4.32±0.10(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1857
Product name: LRE1
Purity: ≥98% (HPLC)
Packaging: 5 mg
Price: $108
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML1857
Product name: LRE1
Purity: ≥98% (HPLC)
Packaging: 25 mg
Price: $436
Updated: 2025/07/31

ChemScene

Product number: CS-0019660
Product name: LRE1
Purity: 99.59%
Packaging: 5mg
Price: $70
Updated: 2021/12/16

Axon Medchem

Product number: Axon2664
Product name: LRE1-RU-0204277
Purity: 98%
Packaging: 10mg
Price: $104.5
Updated: 2021/12/16

ChemScene

Product number: CS-0019660
Product name: LRE1
Purity: 99.59%
Packaging: 10mg
Price: $120
Updated: 2021/12/16

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LRE1 Chemical Properties,Usage,Production

Description

T15787, also known as LRE1, is a novel specific and allosteric inhibitor of soluble adenylyl cyclase (sAC), binding to the bicarbonate activator binding site and inhibiting sAC via a unique allosteric mechanism, preventing sAC-dependent processes in cellular and physiological systems.

Uses

LRE1 is a specific and allosteric inhibitor of soluble adenylyl cyclase.

References

[1] Ramos-Espiritu L, et al. Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase. Nat Chem Biol. 2016 Oct;12(10):838-44. DOI:10.1038/nchembio.2151

LRE1 Preparation Products And Raw materials

Raw materials

Preparation Products

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LRE1 Suppliers

China 29 United States 2 USA 1 Global 32

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 9186
Advantage: 58

Shanghai Yu Ben Biotechnology Co., Ltd.

Tel: 021-61350663 15502154572
Fax: -
Email: 1639466865@qq.com
Country: China
ProdList: 498
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32470
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Jingmo (Xiamen) Biotechnology Co., Ltd

Tel: 13621943973; 13621943973
Email: sales@jamxmpharmatech.com
Country: China
ProdList: 1169
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44894
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 59936
Advantage: 58

1252362-53-0, LRE1Related Search:

LRE1

LRE1 - RU-0204277

2,4-Pyrimidinediamine, 6-chloro-N4-cyclopropyl-N4-(2-thienylmethyl)-

LRE1 >=98% (HPLC)

6-Chloro-N4-cyclopropyl-N4-(thiophen-2-ylmethyl)pyrimidine-2,4-diamine

LRE1, 10 mM in DMSO

6-Chloro-4-N-cyclopropyl-4-N-(thiophen-2-ylmethyl)pyrimidine-2,4-diamine

1252362-53-0