ChemicalBook > CAS DataBase List > MRT-92 HCl salt
MRT-92 HCl salt
- Product Name
- MRT-92 HCl salt
- CAS No.
- 1428307-52-1
- Chemical Name
- MRT-92 HCl salt
- Synonyms
- MRT-92 HCl salt
- CBNumber
- CB63313503
- Molecular Formula
- C33H35ClN4O5
- Formula Weight
- 603.12
- MOL File
- 1428307-52-1.mol
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MRT-92 HCl salt Chemical Properties,Usage,Production
Description
MRT-92 is a potent and selective Smoothened (Smo) receptor inhibitor. MRT-92 displays subnanomolar antagonist activity against Smo in various Hh cell-based assays. MRT-92 inhibits rodent cerebellar granule cell proliferation induced by Hh pathway activation through pharmacologic (half maximal inhibitory concentration [IC50] = 0.4 nM) or genetic manipulation. Smo is the target of anticancer drugs that bind to a long and narrow cavity in the 7-transmembrane (7TM) domain.
MRT-92 HCl salt Preparation Products And Raw materials
Raw materials
Preparation Products
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