ChemicalBook > CAS DataBase List > (6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN

(6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN

Product Name
(6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN
CAS No.
259869-55-1
Chemical Name
(6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN
Synonyms
JWH 133;JW 133;CS-317;JWH 133, >=98%;JWH 133 (in Tocrisolve 100);JWH 133 (in Tocrisolve(TM) 100);JW 133 (10 mg/mL in Methyl Acetate);3-(1,1-Dimethylbutyl)-1-deoxy-Δ8-THC;3-(1,1-Dimethylbutyl)-1-deoxy-Δ8-tetrahydrocannabinol;(6aR,10aR)-6,6,9-trimethyl-3-(2-methylpentan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromene
CBNumber
CB6332673
Molecular Formula
C22H32O
Formula Weight
312.49
MOL File
259869-55-1.mol
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(6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN Property

Boiling point:
382.0±42.0 °C(Predicted)
Density 
0.950±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Chloroform, Ethyl Acetate
form 
Oil
color 
Clear Colorless
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML3627
Product name
JWH-133
Purity
≥98% (HPLC)
Packaging
5MG
Price
$129
Updated
2024/03/01
Sigma-Aldrich
Product number
SML3627
Product name
JWH-133
Purity
≥98% (HPLC)
Packaging
25MG
Price
$519
Updated
2024/03/01
Cayman Chemical
Product number
10005428
Product name
JWH 133
Purity
≥95%
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
10005428
Product name
JWH 133
Purity
≥95%
Packaging
5mg
Price
$151
Updated
2024/03/01
Cayman Chemical
Product number
10005428
Product name
JWH 133
Purity
≥95%
Packaging
10mg
Price
$243
Updated
2024/03/01
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(6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN Chemical Properties,Usage,Production

Uses

JW 133 is an intermediate used to synthesize potent CB2-Selective Cannabinoid Receptor Ligands such as 4-oxo-1,4-dihydroquinoline-3-carboxamides and 3-(1'',1''-Dimethylbutyl)-1-deoxy-Δ8-THC analogs.

Definition

ChEBI: JWH-133 is a dibenzopyran that is Delta(9)-tetrahydrocannabinol which is lacking the hydroxy group and in which the pentyl group at position 3 has been replaced by a 1,1-dimethylbutyl group. A potent and highly selective CB2 receptor agonist. It has a role as a CB2 receptor agonist, an antineoplastic agent, a vasodilator agent, an anti-inflammatory agent, an apoptosis inhibitor, an analgesic and an opioid analgesic. It is a dibenzopyran, an organic heterotricyclic compound and a benzochromene.

Biological Activity

Potent CB 2 selective agonist (K i = 3.4 nM). Approx. 200-fold selective over CB 1 receptors. Active in vivo , reducing spasticity in a murine model of multiple sclerosis. Also available in water soluble emulsion ((6aR,10aR)-3-(1,1-dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran ).

storage

Store at -20°C

(6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN Preparation Products And Raw materials

Raw materials

Preparation Products

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(6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN Suppliers

China 31 Germany 2 Japan 1 Switzerland 1 The Netherlands 1 United Kingdom 2 United States 10 USA 1 Global 49
Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Tocris Bioscience
Tel
--
Fax
--
Email
customerservice@tocris.co.uk
Country
United Kingdom
ProdList
5726
Advantage
77
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View Lastest Price from (6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN manufacturers

Career Henan Chemical Co
Product
(6aR,10aR)-6,6,9-trimethyl-3-(2-methylpentan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromene 259869-55-1
Price
US $1.00/KG
Min. Order
1KG
Purity
Min98% HPLC
Supply Ability
g/kg/ton
Release date
2019-12-20

259869-55-1, (6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRANRelated Search:

tert-Butylhydroquinone HU-210 Ajulemic acid (6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN L-759,633 (6AR,10AR)-6A,7,10,10A-TETRAHYDRO-3-[5-(1H-IMIDAZOL-1-YL)-1,1-DIMETHYLPENTYL]-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN-1-OL HYDROCHLORIDE

  • (6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN
  • JWH 133
  • 6H-Dibenzo[b,d]pyran, 3-(1,1-diMethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-triMethyl-, (6aR,10aR)-
  • 3-(1,1-Dimethylbutyl)-1-deoxy-Δ8-tetrahydrocannabinol
  • 3-(1,1-Dimethylbutyl)-1-deoxy-Δ8-THC
  • JWH 133, >=98%
  • (6aR,10aR)-3-(1,1-Dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-(6H)-dibenzo[b.d]pyrane
  • 3-(1,1-Dimethylbutyl)-1-deoxy-Δ8-THC, 3-(1,1-Dimethylbutyl)-1-deoxy-Δ8-tetrahydrocannabinol
  • JW 133
  • JWH 133 (in Tocrisolve(TM) 100)
  • JWH 133 (in Tocrisolve 100)
  • JW 133 (10 mg/mL in Methyl Acetate)
  • (6aR,10aR)-6,6,9-trimethyl-3-(2-methylpentan-2-yl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromene
  • (6aR,10aR)-6,6,9-trimethyl-3-(2-methylpentan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromene
  • CS-317
  • 259869-55-1
  • C22H32O
  • Cannabinoid receptor
  • Cannabinoids