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[1,1'-Biphenyl]-3-carboxamide, 6-(1-aminoethyl)-4'-fluoro-N-4-pyridinyl-

Product Name
[1,1'-Biphenyl]-3-carboxamide, 6-(1-aminoethyl)-4'-fluoro-N-4-pyridinyl-
CAS No.
934387-35-6
Chemical Name
[1,1'-Biphenyl]-3-carboxamide, 6-(1-aminoethyl)-4'-fluoro-N-4-pyridinyl-
Synonyms
ROCK-IN-1;ROCK IN 1,ROCKIN1;[1,1'-Biphenyl]-3-carboxamide, 6-(1-aminoethyl)-4'-fluoro-N-4-pyridinyl-
CBNumber
CB63339536
Molecular Formula
C20H18FN3O
Formula Weight
335.3748232
MOL File
934387-35-6.mol
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[1,1'-Biphenyl]-3-carboxamide, 6-(1-aminoethyl)-4'-fluoro-N-4-pyridinyl- Property

storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Solid
color 
White to light yellow
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Hazard and Precautionary Statements (GHS)

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[1,1'-Biphenyl]-3-carboxamide, 6-(1-aminoethyl)-4'-fluoro-N-4-pyridinyl- Chemical Properties,Usage,Production

Uses

ROCK-IN-1 is a potent inhibitor of ROCK, with an IC50 of 1.2 nM for ROCK2.

IC 50

ROCK2: 1.2 nM (IC50)

References

[1] Boland S, et al. 3-[2-(Aminomethyl)-5-[(pyridin-4-yl)carbamoyl]phenyl] benzoates as soft ROCK inhibitors. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6442-6. DOI:10.1016/j.bmcl.2013.09.040

[1,1'-Biphenyl]-3-carboxamide, 6-(1-aminoethyl)-4'-fluoro-N-4-pyridinyl- Preparation Products And Raw materials

Raw materials

Preparation Products

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[1,1'-Biphenyl]-3-carboxamide, 6-(1-aminoethyl)-4'-fluoro-N-4-pyridinyl- Suppliers

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934387-35-6, [1,1'-Biphenyl]-3-carboxamide, 6-(1-aminoethyl)-4'-fluoro-N-4-pyridinyl-Related Search:


  • [1,1'-Biphenyl]-3-carboxamide, 6-(1-aminoethyl)-4'-fluoro-N-4-pyridinyl-
  • ROCK-IN-1
  • ROCK IN 1,ROCKIN1
  • 934387-35-6