CDC801

Product Name: CDC801
CAS No.: 192819-27-5
Chemical Name: CDC801
Synonyms: CDC801;CDC801, 10 mM in DMSO;3-(3-cyclopentyloxy-4-methoxyphenyl)-3-(1,3-dioxoisoindol-2-yl)propanamide;2H-Isoindole-2-propanamide, β-[3-(cyclopentyloxy)-4-methoxyphenyl]-1,3-dihydro-1,3-dioxo-
CBNumber: CB63339637
Molecular Formula: C23H24N2O5
Formula Weight: 408.45
MOL File: 192819-27-5.mol

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CDC801 Property

Melting point:: 165-166 °C
Boiling point:: 639.7±55.0 °C(Predicted)
Density: 1.325±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
pka: 16.06±0.40(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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CDC801 Chemical Properties,Usage,Production

Uses

CDC801 is a potent and orally active phosphodiesterase 4 (PDE4) and tumor necrosis factor-α (TNF-α) inhibitor with IC50 of 1.1 μM and 2.5 μM, respectively.

IC 50

PDE4

References

[1] Man HW, et al. Discovery of (S)-N-[2-[1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl] acetamide (apremilast), a potent and orally active phosphodiesterase 4and tumor necrosis factor-alpha inhibitor. J Med Chem. 2009 Mar 26;52(6):1522-4. DOI:10.1021/jm900210d

CDC801 Preparation Products And Raw materials

Raw materials

Preparation Products

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CDC801 Suppliers

China 20 United States 4 USA 1 Global 25

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192819-27-5, CDC801Related Search:

CDC801

3-(3-cyclopentyloxy-4-methoxyphenyl)-3-(1,3-dioxoisoindol-2-yl)propanamide

2H-Isoindole-2-propanamide, β-[3-(cyclopentyloxy)-4-methoxyphenyl]-1,3-dihydro-1,3-dioxo-

CDC801, 10 mM in DMSO

192819-27-5