ChemicalBook > CAS DataBase List > SS5020
SS5020
- Product Name
- SS5020
- CAS No.
- 1334310-70-1
- Chemical Name
- SS5020
- Synonyms
- SS5020;2-Propenoic acid, 3-[4-[(7-hydroxy-2-oxo-3-phenyl-2H-1-benzopyran-4-yl)methyl]phenyl]-, (2E)-
- CBNumber
- CB63345566
- Molecular Formula
- C25H18O5
- Formula Weight
- 398.41
- MOL File
- 1334310-70-1.mol
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SS5020 Property
- Boiling point:
- 679.5±55.0 °C(Predicted)
- Density
- 1.375±0.06 g/cm3(Predicted)
- pka
- 4.50±0.10(Predicted)
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SS5020 Chemical Properties,Usage,Production
Description
SS5020 is a a new benzopyran antiestrogen. Unlike tamoxifen (TAM), SS5020 exhibits no genotoxic activity to damage DNA. Furthermore, SS5020 does not present significant uterotrophic potential in rats; in contrast, the structurally related compounds, TAM, toremifene, raloxifene (RAL) and SP500263 all have uterotrophic activity. At the human equivalent molar dose of TAM (0.33 or 1.0 mg/kg), SS5020 had much stronger antitumor potential than those same antiestrogens against 7,12-dimethylbenz(a)anthracene-induced mammary carcinoma in rats.
SS5020 Preparation Products And Raw materials
Raw materials
Preparation Products
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