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Iodopropynyl butylcarbamate

Product Name
Iodopropynyl butylcarbamate
CAS No.
55406-53-6
Chemical Name
Iodopropynyl butylcarbamate
Synonyms
IPBC;3-IODO-2-PROPYNYL BUTYLCARBAMATE;3-IODO-2-PROPYNYL N-BUTYLCARBAMATE;IBP;lodopropynyl butylcarbamate;IODOCARB;troysanpolyphaseanti-mildew;IPBC-99;woodlife;PERMATOX
CBNumber
CB6334602
Molecular Formula
C8H12INO2
Formula Weight
281.09
MOL File
55406-53-6.mol
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Iodopropynyl butylcarbamate Property

Melting point:
64-68 °C(lit.)
Boiling point:
321.8±25.0 °C(Predicted)
Density 
1.606±0.06 g/cm3(Predicted)
vapor pressure 
0.005Pa at 25℃
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
soluble in Methanol
pka
12.03±0.46(Predicted)
color 
White to Almost white
Water Solubility 
168mg/L at 20℃
Merck 
14,5069
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
WYVVKGNFXHOCQV-UHFFFAOYSA-N
LogP
2.81 at 25℃
CAS DataBase Reference
55406-53-6(CAS DataBase Reference)
EPA Substance Registry System
3-Iodo-2-propynyl butylcarbamate (55406-53-6)
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Safety

Hazard Codes 
N
Risk Statements 
50/53-50
Safety Statements 
60-61-29
RIDADR 
3077
WGK Germany 
3
RTECS 
EZ0950000
HazardClass 
9
PackingGroup 
III
HS Code 
29241990
Hazardous Substances Data
55406-53-6(Hazardous Substances Data)
Toxicity
LD50 orally in rats: 1580 mg/kg; dermally in rabbit: >2000 mg/kg; LC50 (96 hr) in bluegill sunfish, rainbow trout, bobwhite quail: 1.12, 0.31, >7683 ppm; LC50 (8 day) in mallard duck: >7182 ppm (Hansen)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

H318Causes serious eye damage

H331Toxic if inhaled

H372Causes damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
521949
Product name
3-Iodo-2-propynyl N-butylcarbamate
Purity
97%
Packaging
10g
Price
$154
Updated
2024/03/01
Sigma-Aldrich
Product number
521949
Product name
3-Iodo-2-propynyl N-butylcarbamate
Purity
97%
Packaging
50g
Price
$433
Updated
2024/03/01
TCI Chemical
Product number
I0666
Product name
3-Iodo-2-propynyl N-Butylcarbamate
Purity
>97.0%(GC)
Packaging
25g
Price
$131
Updated
2024/03/01
TCI Chemical
Product number
I0666
Product name
3-Iodo-2-propynyl N-Butylcarbamate
Purity
>97.0%(GC)
Packaging
100g
Price
$328
Updated
2024/03/01
Sigma-Aldrich
Product number
90865
Product name
3-Iodo-2-propynyl N-butylcarbamate
Purity
analytical standard
Packaging
100mg
Price
$109
Updated
2024/03/01
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Iodopropynyl butylcarbamate Chemical Properties,Usage,Production

Description

Iodopropynyl butylcarbamate is a preservative that has been used as an industrial fungicide since the 1970s and more recently has been combined with formaldehydereleasing agents for use in cosmetics. The North American Contact Dermatitis Group patch tested with 0.1%iodopropynyl butylcarbamate in petrolatum and found 0.2% of their patch test clinic patients had positive reactions to this chemical. Most cosmetic applications appear to require less than 0.012% of this preservative.

Chemical Properties

Liquid

Uses

Glycacil(R) 2000 is used as a preservative in personal care formulations.

Uses

Glycacil(R) L is used as a preservative in personal care formulations.

Uses

Glycacil(R) S is used as a preservative in personal care formulations.

Uses

iodopropynyl butylcarbamate is a preservative with broad fungicidal activity used in skin care products. It is recommended for use in difficult formulation systems.

Uses

An antibacterial agent.

Uses

Fungicide; mildewcide; preservative in cosmetics, paints and coatings, metal working fluids; wood protection.

Application

1. Cosmetics 2. Wood preservatives 3. Paints 4. Metalworking fluids 5. Household products 6. Moistened toilet tissues 7. Contact lenses 8. Building materials 9. Cooling water 10. Adhesives 11. Textiles 12. Paper

Definition

ChEBI: A carbamate ester that is carbamic acid in which the nitrogen has been substituted by a butyl group and in which the hydrogen of the carboxy group is replaced by a 1-iodoprop-2-yn-3-yl group. A fungicide, it is used as a preservative and sapstain control c emical in wood products and as a preservative in adhesives, paints, latex paper coating, plastic, water-based inks, metal working fluids, textiles, and numerous consumer products.

General Description

Off-white solid.

Reactivity Profile

Iodopropynyl butylcarbamate is a carbamate ester. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates.

Flammability and Explosibility

Not classified

Contact allergens

Iodopropynyl butylcarbamate has produced slight irritation in rabbits. However, it was not found to be either a skin sensitizer or a photo sensitizer in guinea pigs. Cosmetic formulations containing up to 0.125% of iodopropynyl butylcarbamate produce no significant irritation or sensitization reactions in human repeated insult patch tests. Iodopropynyl butylcarbamate did not cause crosssensitization reactions in patients who had demonstrated sensitivity to related dithiocarbamate compounds. In the European Union, it is approved as a preservative up to 0.05% and is not to be used in oral hygiene or lip care products. If the concentration exceeds 0.02% in leave-on products, a warning label must indicate that the product contains iodine.

Contact allergens

Iodopropynyl butylcarbamate (IPBC) is a broad-spec- trum preservative used for years because of its wide field of application, in polymer emulsions and pigment dispersions such as water-based paints and adhesives, cements and inks, as a wood preservative, in metal- working fluids, household products, and cosmetics. Allergic contact dermatitis to IPBC was reported due to cosmetics, from sanitary wipes, and in metalworkers.

Clinical Use

Iodopropynyl butylcarbamate (3-iodo-2-propynyl-butylcarbamate) is a highly effective fungicide as well as a bactericide. It was first used in the 1970s as a film fungicide for paint and then as a wood preservative, where final use concentration up to 4% was permitted. For paint and coatings usually no more than 0.5% iodopropynyl butylcarbamate is used. For metalworking fluids, adhesives, textiles, and paper, concentrations between 0.1%and 0.2% are common. The Cosmetic Ingredient Review Expert Panel concluded that iodopropynyl butylcarbamate is safe as a cosmetic ingredient in concentrations less than or equal to 0.1%and that it should not be used in products intended to be aerosolized. By 1996, iodopropynyl butylcarbamate was used in 122 formulations reported to the United States Food and Drug Administration. Iodopropynyl butylcarbamate is found in a wide variety of occupational and consumer products, including shampoos, lotions, powders, makeup, baby products, paints, coatings, metalworking fluids, household products, cooling water, building materials, and contact lenses. It is an irritant, although at low concentrations few problems have been reported.

Iodopropynyl butylcarbamate Preparation Products And Raw materials

Raw materials

Preparation Products

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Iodopropynyl butylcarbamate Suppliers

Wuhan Xinli Biotechnology Co., Ltd
Tel
027-027-83305579 13697349395
Fax
027-83305570
Email
409374507@qq.com
Country
China
ProdList
27
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2208
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19179
Advantage
64
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View Lastest Price from Iodopropynyl butylcarbamate manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Iodopropynyl butylcarbamate 55406-53-6
Price
US $20.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20MT
Release date
2024-04-22
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Iodopropynyl butylcarbamate 55406-53-6
Price
US $0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
500kg/month
Release date
2023-01-09
Hebei Weibang Biotechnology Co., Ltd
Product
Iodopropynyl butylcarbamate 55406-53-6
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 mt
Release date
2024-10-28

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