[glycyl-κN-L-histidyl-κN,κN3-L-lysinato(2-)]-Copper, monoacetate (9CI)

Product Name: [glycyl-κN-L-histidyl-κN,κN3-L-lysinato(2-)]-Copper, monoacetate (9CI)
CAS No.: 300801-03-0
Chemical Name: [glycyl-κN-L-histidyl-κN,κN3-L-lysinato(2-)]-Copper, monoacetate (9CI)
Synonyms: GHK-Cuacetat;Unii-DL1TR6W6VM;GHK-Cu (acetate);GHK-CU (1:1) acetate salt;Glycyl-L-Histidyl-L-Lysine Copper acetate(1:1);N2-(N-glycyl-L-histidyl)-L-Lysine,coppercomplex,acetate;[glycyl-κN-L-histidyl-κN,κN3-L-lysinato(2-)]-Copper, monoacetate (9CI);(2S)-6-amino-2-[[(2S)-2-[(2-aminoacetyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoate
CBNumber: CB63361115
Molecular Formula: C16H25CuN6O6
Formula Weight: 460.96
MOL File: 300801-03-0.mol

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[glycyl-κN-L-histidyl-κN,κN3-L-lysinato(2-)]-Copper, monoacetate (9CI) Property

storage temp.: Store at -20°C
solubility: PBS (pH 7.2): 5 mg/ml
form: A solid
InChIKey: DKCRJQSNYITGOA-ZVYQBGMQNA-L
SMILES: C(=O)(O)C.C([C@@H]1CC2=CNC=N2[Cu+2]2NCC(=O)[N-]12)(=O)N[C@H](C(=O)[O-])CCCCN |&1:5,20,r|

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 28259
Product name: GHK-Cu (acetate)
Packaging: 50mg
Price: $50
Updated: 2024/03/01

Cayman Chemical

Product number: 28259
Product name: GHK-Cu (acetate)
Packaging: 100mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 28259
Product name: GHK-Cu (acetate)
Packaging: 25mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 28259
Product name: GHK-Cu (acetate)
Packaging: 250mg
Price: $139
Updated: 2024/03/01

AK Scientific

Product number: Z3198
Product name: GHK-Cu
Packaging: 50mg
Price: $154
Updated: 2021/12/16

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[glycyl-κN-L-histidyl-κN,κN3-L-lysinato(2-)]-Copper, monoacetate (9CI) Chemical Properties,Usage,Production

Description

GHK-Cu acetate is a complex of the tripeptide Gly-His-Lys and a copper(II) ion that has wound healing and anti-inflammatory activities. It increases proliferation and the levels of collagen and secreted pro-matrix metalloproteinase-2 (MMP-2) in isolated human fibroblasts. GHK-Cu increases levels of collagen and glycosaminoglycans (GAGs) and the expression of decorin in the wound tissue of rats. It decreases LPS-induced increases in the levels of reactive oxygen species (ROS), IL-6, and TNF-α in RAW 264.7 cells when used at a concentration of 10 μM.3 GHK-Cu (10 μg/g) prevents LPS-induced decreases in lung superoxide dismutase (SOD) activity and glutathione (GSH) levels and reduces LPS-induced increases in the number of cells and the level of total protein in bronchoalveolar lavage fluid (BALF) in a mouse model of acute lung injury.

Uses

Copper tripeptide (GHK-Cu) acetate is a tripeptide. During wound healing, Copper tripeptide acetate may be freed from existing extracellular proteins via proteolysis and serves as a chemoattractant for inflammatory and endothelial cells. Copper tripeptide acetate has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Copper tripeptide acetate is a natural modulator of multiple cllular pathways in skin regeneration[1].

References

[1] Pollard JD, et al. Effects of copper tripeptide on the growth and expression of growth factors by normal and irradiated fibroblasts. Arch Facial Plast Surg. 2005 Jan-Feb;7(1):27-31. DOI:10.1001/archfaci.7.1.27

[glycyl-κN-L-histidyl-κN,κN3-L-lysinato(2-)]-Copper, monoacetate (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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[glycyl-κN-L-histidyl-κN,κN3-L-lysinato(2-)]-Copper, monoacetate (9CI) Suppliers

China 30 United States 1 Global 31

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View Lastest Price from [glycyl-κN-L-histidyl-κN,κN3-L-lysinato(2-)]-Copper, monoacetate (9CI) manufacturers

Wuhan Nutra Biotechnology Co.,Ltd

Product: GHK-Cu (acetate) 300801-03-0
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 100kgs
Release date: 2021-05-24

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