AZD5991

Product Name: AZD5991
CAS No.: 2143010-83-5
Chemical Name: AZD5991
Synonyms: AZD5991;AZD5991 ，S8643;AZD-5991 Racemate;AZD 5991 Racemate,AZD5991 Racemate;22H-9,4,8-(Metheniminomethyno)-14,20:26,23-dimetheno-10H,20H-pyrazolo[4,3-l][2,15,22,18,19]benzoxadithiadiazacyclohexacosine-32-carboxylic acid, 5-chloro-2,11,12,24,27,29-hexahydro-2,3,24,33-tetramethyl-
CBNumber: CB63364606
Molecular Formula: C35H34ClN5O3S2
Formula Weight: 672.26
MOL File: 2143010-83-5.mol

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AZD5991 Property

Boiling point:: 949.6±65.0 °C(Predicted)
Density: 1.42±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO

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Hazard and Precautionary Statements (GHS)

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AZD5991 Chemical Properties,Usage,Production

Uses

AZD-5991 Racemate is the racemate of AZD-5991. AZD-5991 Racemate is a Mcl-1 inhibitor with an IC50 of <3 nM in FRET assay.

IC 50

Mcl-1: 3 nM (IC₅₀)

References

[1] Tron AE, et al. Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia. Nat Commun. 2018 Dec 17;9(1):5341. DOI:10.1038/s41467-018-07551-w

AZD5991 Preparation Products And Raw materials

Raw materials

Preparation Products

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AZD5991 Suppliers

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2143010-83-5, AZD5991Related Search:

AZD5991

AZD-5991 Racemate

22H-9,4,8-(Metheniminomethyno)-14,20:26,23-dimetheno-10H,20H-pyrazolo[4,3-l][2,15,22,18,19]benzoxadithiadiazacyclohexacosine-32-carboxylic acid, 5-chloro-2,11,12,24,27,29-hexahydro-2,3,24,33-tetramethyl-

AZD 5991 Racemate,AZD5991 Racemate

AZD5991 ，S8643

2143010-83-5

C35H34ClN5O3S2