ChemicalBook > CAS DataBase List > CB-1158

CB-1158

Product Name
CB-1158
CAS No.
2095732-06-0
Chemical Name
CB-1158
Synonyms
INCB01158;Numidargistat;CB-1158 (Numidargistat);Numidargistat (CB1158, INCB01158);Numidargistat 2HCl (CB1158, INCB01158);(3R,4S)-1-(L-alanyl)-3-amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic acid;3-Pyrrolidinecarboxylic acid, 3-amino-1-[(2S)-2-amino-1-oxopropyl]-4-(3-boronopropyl)-, (3R,4S)-;(3R,4S)-3-Amino-1-[(2S)-2-aminopropanoyl]-4-[3-(dihydroxyboranyl)propyl]pyrrolidine-3-carboxylic acid
CBNumber
CB63364611
Molecular Formula
C11H22BN3O5
Formula Weight
287.12
MOL File
2095732-06-0.mol
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CB-1158 Property

Boiling point:
574.1±60.0 °C(Predicted)
Density 
1.299±0.06 g/cm3(Predicted)
pka
2.13±0.40(Predicted)
form 
Solid
color 
Off-white to light yellow
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Hazard and Precautionary Statements (GHS)

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CB-1158 Chemical Properties,Usage,Production

Uses

(3R,4S)-3-Amino-1-[(2S)-2-amino-1-oxopropyl]-4-(3-boronopropyl)-3-pyrrolidinecarboxylic Acid Dihydrochloride is a salt analog of (3R,4S)-3-Amino-1-[(2S)-2-amino-1-oxopropyl]-4-(3-boronopropyl)-3-pyrrolidinecarboxylic Acid (CAS# 2095732-06-0), which inhibits arginase 1 (Arg1) enzyme and blocks myeloid cell-??mediated immune suppression in the tumor microenvironment.

CB-1158 Preparation Products And Raw materials

Raw materials

Preparation Products

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CB-1158 Suppliers

ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185 18149758185
Email
sales-cpd@caerulumpharma.com
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China
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3466
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Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
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+86-21-52996696
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China
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4587
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Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
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info@efebio.com
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China
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9804
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58
Shanghai Shanyuan pharmaceutical technology co., LTD
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021-31761238 13167072949
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021-31761238
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3146446224@qq.com
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China
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1649
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Nanjing Xinmeihe Pharmaceutical Co., Ltd.
Tel
025-57672321 13739186949
Fax
025-57672123
Email
2548785915@qq.com
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China
ProdList
298
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58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
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China
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9729
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58
Guangzhou Younan Technology Co., Ltd
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020-82000279 18988968278
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QQ:3283937693
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sales@ubiochem.com
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China
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Shanghai hongqu biomedical technology co. LTD
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88888888888
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hongquchem@qq.com
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China
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5132
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Wuhan Topule
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+86-02787215551 +86-19945035818
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027-87215551
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2936752263@qq.com
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Changzhou Furuisi Biotechnology Co., Ltd
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0519-85524369
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3477467573@qq.com
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Hubei Kele Fine Chemical Co., Ltd
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027-59101668 19945030958
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027-59101668
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2881924765@qq.com
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China
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SHENZHEN REISCH BIOTECH CO., LTD
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0755-0755-28609002 15112530219
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1179151648@qq.com
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China
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InvivoChem
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13549236410
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sales@invivochem.cn
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China
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TargetMol Chemicals Inc.
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4008200310
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marketing@tsbiochem.com
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Shanghai Tachizaki Biomedical Research Center
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18014399201
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Wuhan Jingkangen Biomedical Technology Co., Ltd
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13720134139 086-15871494362 13720134139
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Nantong QuanYi Biotechnology Co., Ltd
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0513-66337626 18051384581
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sales@chemhifuture.com
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Nanjing Shizhou Biology Technology Co.,Ltd
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Changsha Fuzhen Biotechnology Co.,LTD
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RD International Technology Co., Limited
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Olix (Shanghai) Pharmaceutical Technology Co., Ltd
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Shanghai Fine Biotech Co.,Ltd
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Wuhan Jingkang en Biomedical Technology Co., Ltd
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Jilin Chinese Academy of Sciences-yanshen Technology
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Wuhan Topule Biopharmaceutical Co., Ltd
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Absin Bioscience Inc.
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chenjw@absin.cn
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2095732-06-0, CB-1158Related Search:


  • (3R,4S)-1-(L-alanyl)-3-amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic acid
  • INCB01158
  • 3-Pyrrolidinecarboxylic acid, 3-amino-1-[(2S)-2-amino-1-oxopropyl]-4-(3-boronopropyl)-, (3R,4S)-
  • Numidargistat (CB1158, INCB01158)
  • Numidargistat 2HCl (CB1158, INCB01158)
  • Numidargistat
  • (3R,4S)-3-Amino-1-[(2S)-2-aminopropanoyl]-4-[3-(dihydroxyboranyl)propyl]pyrrolidine-3-carboxylic acid
  • CB-1158 (Numidargistat)
  • 2095732-06-0
  • C11H22BN3O5
  • pyrolidine