ChemicalBook > CAS DataBase List > CB-1158
CB-1158
- Product Name
- CB-1158
- CAS No.
- 2095732-06-0
- Chemical Name
- CB-1158
- Synonyms
- INCB01158;Numidargistat;Numidargistat (CB1158, INCB01158);Numidargistat 2HCl (CB1158, INCB01158);(3R,4S)-1-(L-alanyl)-3-amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic acid;3-Pyrrolidinecarboxylic acid, 3-amino-1-[(2S)-2-amino-1-oxopropyl]-4-(3-boronopropyl)-, (3R,4S)-;(3R,4S)-3-Amino-1-[(2S)-2-aminopropanoyl]-4-[3-(dihydroxyboranyl)propyl]pyrrolidine-3-carboxylic acid
- CBNumber
- CB63364611
- Molecular Formula
- C11H22BN3O5
- Formula Weight
- 287.12
- MOL File
- 2095732-06-0.mol
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CB-1158 Property
- Boiling point:
- 574.1±60.0 °C(Predicted)
- Density
- 1.299±0.06 g/cm3(Predicted)
- pka
- 2.13±0.40(Predicted)
- form
- Solid
- color
- Off-white to light yellow
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CB-1158 Chemical Properties,Usage,Production
Uses
(3R,4S)-3-Amino-1-[(2S)-2-amino-1-oxopropyl]-4-(3-boronopropyl)-3-pyrrolidinecarboxylic Acid Dihydrochloride is a salt analog of (3R,4S)-3-Amino-1-[(2S)-2-amino-1-oxopropyl]-4-(3-boronopropyl)-3-pyrrolidinecarboxylic Acid (CAS# 2095732-06-0), which inhibits arginase 1 (Arg1) enzyme and blocks myeloid cell-??mediated immune suppression in the tumor microenvironment.
CB-1158 Preparation Products And Raw materials
Raw materials
Preparation Products
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