ChemicalBook > CAS DataBase List > 2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1)
2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1)
- Product Name
- 2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1)
- CAS No.
- 1369427-40-6
- Chemical Name
- 2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1)
- Synonyms
- Boc-Dap-OH.DCHA;N-Boc-Dolaproline DCHA;N-Boc-dolaproine (dicyclohexylamine);N-Boc-(2R,3R,4S)-dolaproine DCHA salt;(2R,3R)-BOC-dolaproine dicyclohexylamine;Dicyclohexylamine (2R,3R)-3-[(S)-1-Boc-2-pyrrolidinyl]-3-methoxy-2-methylpropanoate;(2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoic acid.DHEA;dicyclohexylamine (2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoate;(2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoic acid N-cyclohexylcyclohexanamine salt;(2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoic acid N-cyclohexylcyclohexanamine salt(1:1)
- CBNumber
- CB63367339
- Molecular Formula
- C26H48N2O5
- Formula Weight
- 468.68
- MOL File
- 1369427-40-6.mol
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2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1) Property
- storage temp.
- 2-8°C, stored under nitrogen, away from moisture
- form
- Solid
- color
- White to off-white
- InChIKey
- PKZALTWOMMNNOL-QNEVMNBPNA-N
- SMILES
- N(C1CCCCC1)C1CCCCC1.[C@@H]([C@]1([H])CCCN1C(=O)OC(C)(C)C)(OC)[C@@H](C)C(=O)O |&1:13,14,29,r|
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2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1) Chemical Properties,Usage,Production
Uses
N-Boc-dolaproine dicyclohexylamine is an amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity. And contains dicyclohexylamine[1].
References
[1] Almeida W P, et al. An easy and stereoselective synthesis of N-Boc-dolaproine via the Baylis–Hillman reaction[J]. Tetrahedron letters, 2003, 44(5): 937-940.
2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1) Preparation Products And Raw materials
Raw materials
Preparation Products
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2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1) Suppliers
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