ChemicalBook > CAS DataBase List > TC-I 2014

TC-I 2014

Product Name
TC-I 2014
CAS No.
1221349-53-6
Chemical Name
TC-I 2014
Synonyms
TC-I 2014;TCI 2014,TC I 2014;VSMFCZZEKTVDHM-UHFFFAOYSA-N;3-[7-(TRIFLUOROMETHYL)-5-[2-(TRIFLUOROMETHYL)PHENYL]-1H-BENZIMIDAZOL-2-YL]-1-OXA-2-AZASPIRO[4.5]DEC-2-ENE;1-Oxa-2-azaspiro[4.5]dec-2-ene, 3-[7-(trifluoromethyl)-5-[2-(trifluoromethyl)phenyl]-1H-benzimidazol-2-yl]-;3-[7-(trifluoromethyl)-5-[2-(trifluoromethyl)phenyl]-1H-1,3-benzodiazol-2-yl]-1-oxa-2-azaspiro[4.5]dec-2-ene;3-(7-(Trifluoromethyl)-5-(2-(trifluoromethyl)phenyl)-1H-benzo[d]imidazol-2-yl)-1-oxa-2-azaspiro[4.5]dec-2-ene
CBNumber
CB63369777
Molecular Formula
C23H19F6N3O
Formula Weight
467.41
MOL File
1221349-53-6.mol
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TC-I 2014 Property

Boiling point:
564.3±60.0 °C(Predicted)
Density 
1.48±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Solid
pka
7.01±0.30(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Tocris
Product number
5410
Product name
TC-I2014
Purity
≥98%(HPLC)
Packaging
10
Price
$217
Updated
2021/12/16
Tocris
Product number
5410
Product name
TC-I2014
Purity
≥98%(HPLC)
Packaging
50
Price
$909
Updated
2021/12/16
TRC
Product number
T012160
Product name
TC-I2014
Packaging
2.5mg
Price
$175
Updated
2021/12/16
Usbiological
Product number
466888
Product name
TC-I 2014
Packaging
1mg
Price
$368
Updated
2021/12/16
Usbiological
Product number
256849
Product name
TC-I 2014
Packaging
10mg
Price
$475
Updated
2021/12/16
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TC-I 2014 Chemical Properties,Usage,Production

Uses

TC-I 2014 is a potent TRPM8 antagonist exhibiting antiallodynic properties in pain models.

in vivo

TC-I 2014 (10 mg/kg, Orally once) completely prevents icilin-induced WDS[1].

Animal Model:TC-I 2014 (10 mg/kg, Orally once) completely prevents icilin-induced WDS[1].
Dosage:3, 5.6, 10 mg/kg.
Administration:Orally once.
Result:Produced greater than 90% inhibition at 3, 5.6, and 10 mg/kg administered 2 h prior to icilin challenge.

storage

Store at +4°C

TC-I 2014 Preparation Products And Raw materials

Raw materials

Preparation Products

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TC-I 2014 Suppliers

Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4827
Advantage
55
Shanghai Beckham Medical Technology Co., Ltd
Tel
13816613772
Fax
QQ: 12922499
Email
huahero21@sina.com
Country
China
ProdList
2586
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
86249
Advantage
60
Jinan Yaoyan Pharmaceutical Co., Ltd.
Tel
Fax
-
Email
jnyaoyan@163.com
Country
China
ProdList
3069
Advantage
58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
Tel
meitaochem@126.com
Email
meitaochem@126.com
Country
China
ProdList
19103
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32467
Advantage
58
Changzhou Chenhong Biotechnology Co., Ltd.
Tel
+86-0519-85788828 +86-13775037613
Email
sales@chemrenpharm.com
Country
China
ProdList
4032
Advantage
58
ShangHai ChuanQian Chemcial Technique Centre
Tel
15869524721
Email
3525679403@qq.com
Country
China
ProdList
4411
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44896
Advantage
58

1221349-53-6, TC-I 2014Related Search:


  • 3-[7-(TRIFLUOROMETHYL)-5-[2-(TRIFLUOROMETHYL)PHENYL]-1H-BENZIMIDAZOL-2-YL]-1-OXA-2-AZASPIRO[4.5]DEC-2-ENE
  • TC-I 2014
  • VSMFCZZEKTVDHM-UHFFFAOYSA-N
  • 1-Oxa-2-azaspiro[4.5]dec-2-ene, 3-[7-(trifluoromethyl)-5-[2-(trifluoromethyl)phenyl]-1H-benzimidazol-2-yl]-
  • TCI 2014,TC I 2014
  • 3-(7-(Trifluoromethyl)-5-(2-(trifluoromethyl)phenyl)-1H-benzo[d]imidazol-2-yl)-1-oxa-2-azaspiro[4.5]dec-2-ene
  • 3-[7-(trifluoromethyl)-5-[2-(trifluoromethyl)phenyl]-1H-1,3-benzodiazol-2-yl]-1-oxa-2-azaspiro[4.5]dec-2-ene
  • 1221349-53-6
  • C23H19F6N3O