ChemicalBook > CAS DataBase List > trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide

trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide

Product Name
trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide
CAS No.
3854-04-4
Chemical Name
trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide
Synonyms
CPD3509;Oxotremorine M (iodide);Oxotremorine M iodide, 10 mM in DMSO;trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide
CBNumber
CB63387012
Molecular Formula
C11H19IN2O
Formula Weight
322.19
MOL File
3854-04-4.mol
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trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide Property

storage temp. 
Desiccate at -20°C
solubility 
DMSO : 125 mg/mL (387.97 mM; Need ultrasonic)
form 
Powder
color 
Light yellow to yellow
Water Solubility 
Soluble to 100 mM in water
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
20847
Product name
Oxotremorine M (iodide)
Purity
≥98%
Packaging
50mg
Price
$72
Updated
2024/03/01
Cayman Chemical
Product number
20847
Product name
Oxotremorine M (iodide)
Purity
≥98%
Packaging
100mg
Price
$128
Updated
2024/03/01
TRC
Product number
O870518
Product name
Oxotremorine M
Packaging
25mg
Price
$140
Updated
2021/12/16
AK Scientific
Product number
1713CA
Product name
(4-(2-Oxo-1-pyrrolidinyl)-2-butynyl)trimethylammoniumiodide
Packaging
50mg
Price
$178
Updated
2021/12/16
AK Scientific
Product number
1713CA
Product name
(4-(2-Oxo-1-pyrrolidinyl)-2-butynyl)trimethylammoniumiodide
Packaging
100mg
Price
$240
Updated
2021/12/16
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trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide Chemical Properties,Usage,Production

Description

Oxotremorine M is a non-selective muscarinic (M) acetylcholine receptor agonist that induces phosphoinositide hydrolysis in mouse ileum isolated from wild-type, M2, M3, and M2/M3 knockout mice (EC50s = 0.36, 0.52, 1.62, and 1.48 μM, respectively). It also increases M4-induced inhibition of calcium currents in NG108-15 mouse neuroblastoma X rat glioma hybrid cells (EC50 = 0.14 μM). Oxotremorine M inhibits KCNQ2/3 potassium currents in Xenopus oocytes expressing M1 receptors and KCNQ2/3 potassium channels (IC50 = 1.1 μM). It also directly inhibits KCNQ2/3 potassium channels, decreasing KCNQ2/3 potassium currents in Xenopus oocytes lacking muscarinic receptors in a dose-dependent manner.

Uses

Oxotremorine M is a muscarinic receptor agonist.

storage

Desiccate at -20°C

trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide Preparation Products And Raw materials

Raw materials

Preparation Products

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trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide Suppliers

CHINA 17 United Kingdom 1 United States 7 USA 1 Global 26
ShangHai Caerulum Pharma Discovery Co., Ltd.
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China
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3854-04-4, trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodideRelated Search:


  • trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide
  • Oxotremorine M (iodide)
  • CPD3509
  • Oxotremorine M iodide, 10 mM in DMSO
  • 3854-04-4