1-(4-FLUOROPHENYL)-2-PYRROLIDINONE

Product Name: 1-(4-FLUOROPHENYL)-2-PYRROLIDINONE
CAS No.: 54660-08-1
Chemical Name: 1-(4-FLUOROPHENYL)-2-PYRROLIDINONE
Synonyms: BUTTPARK 32\07-63;1-(4-FLUOROPHENYL)-2-PYRROLIDINONE;1-(4-Fluorophenyl)pyrrolidin-2-one;1-(4-Fluorophenyl)-2-pyrrolidone97%;1-(4-Fluorophenyl)-2-pyrrolidone 97%;2-Pyrrolidinone, 1-(4-fluorophenyl)-;1-(4-Fluorophenyl)pyrrolidin-2-one 97%;1-(4-FLUOROPHENYL)-2-PYRROLIDINONE 99+%;1-(4-Fluorophenyl)pyrrolidin-2-one 95+%;1-(4-Fluorophenyl)-2-oxopyrrolidine, 1-Fluoro-4-(2-oxopyrrolidin-1-yl)benzene
CBNumber: CB6348193
Molecular Formula: C10H10FNO
Formula Weight: 179.19
MOL File: 54660-08-1.mol

More

Less

1-(4-FLUOROPHENYL)-2-PYRROLIDINONE Property

Melting point:: 55-58 °C
Density: 1.1545 (estimate)
storage temp.: Sealed in dry,Room Temperature
Appearance: White to off-white Solid

More

Less

Safety

Hazard Codes: Xi,Xn
Risk Statements: 22
Safety Statements: 24/25
Hazard Note: Irritant
HS Code: 29339980

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

More

Less

N-Bromosuccinimide Price

Apolloscientific

Product number: PC9696
Product name: 1-(4-Fluorophenyl)pyrrolidin-2-one
Purity: 95+%
Packaging: 1g
Price: $65
Updated: 2021/12/16

AK Scientific

Product number: 5393AE
Product name: 1-(4-Fluorophenyl)pyrrolidin-2-one
Packaging: 250mg
Price: $94
Updated: 2021/12/16

Oakwood

Product number: 005898
Product name: 1-(4-Fluorophenyl)-2-pyrrolidinone
Packaging: 1g
Price: $99
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H48-3-Z6
Product name: 1-(4-Fluorophenyl)-2-pyrrolidone
Purity: 97%
Packaging: 1g
Price: $104
Updated: 2021/12/16

Apolloscientific

Product number: PC9696
Product name: 1-(4-Fluorophenyl)pyrrolidin-2-one
Purity: 95+%
Packaging: 5g
Price: $130
Updated: 2021/12/16

More

Less

1-(4-FLUOROPHENYL)-2-PYRROLIDINONE Chemical Properties,Usage,Production

Chemical Properties

beige crystalline powder

Synthesis

616-45-5

352-34-1

54660-08-1

General procedure for the synthesis of 1-(4-fluorophenyl)-2-pyrrolidinone from 2-pyrrolidinone and p-fluoroiodobenzene: N-nucleophilic reagent (2.21 mmol), Cu2O (Sigma-Aldrich, 99.99% purity, 0.147-0.294 mmol), K3PO4 (2.94 mmol), aryl halide (1.47 mmol), phase transfer catalyst (0.147-0.294 mmol) and water (0.40 mL) were sequentially added to the reaction vial and sealed by installing a screw cap. The reaction mixture was stirred in a closed system at 130 °C for 24 h under air atmosphere. Upon completion of the reaction, the non-homogeneous mixture was cooled to room temperature and diluted with dichloromethane. The resulting solution was filtered directly through diatomaceous earth. The organic extracts were combined, dried with anhydrous Na2SO4 and concentrated under reduced pressure to remove the solvent. The crude product was purified by silica gel column chromatography to afford the N-arylated product 1-(4-fluorophenyl)-2-pyrrolidinone. The structure and purity of the product were confirmed by 1H NMR and 13C NMR spectral analysis.

References

[1] Tetrahedron Letters, 2011, vol. 52, # 11, p. 1169 - 1172
[2] Synlett, 2015, vol. 26, # 12, p. 1697 - 1701
[3] Advanced Synthesis and Catalysis, 2018, vol. 360, # 11, p. 2178 - 2182

1-(4-FLUOROPHENYL)-2-PYRROLIDINONE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

1-(4-FLUOROPHENYL)-2-PYRROLIDINONE Suppliers

Belgium 1 China 30 France 1 Germany 1 India 2 Japan 1 United Kingdom 7 United States 9 Global 52

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

Tel: +86-21-54098501
Fax: +86-21-54096319
Email: sales@sinch.com.cn
Country: China
ProdList: 11598
Advantage: 64

ShangHai AmK Pharmaceutical Technology Co., Ltd.

Tel: 微信 17321281695 18019252918
Fax: 17321281695
Email: sale@amkchem.com
Country: China
ProdList: 15136
Advantage: 55

Zhengzhou Alfachem Co., Ltd.

Tel: 0371-53765687 18937137882
Fax: QQ:2885373884
Email: 2853979813@qq.com
Country: China
ProdList: 7992
Advantage: 55

Wuhan Chemwish Technology Co.， Ltd

Tel: 027-67849912
Fax: 027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 9148
Advantage: 60

Changzhou Hopschain Chemical Co.,Ltd.

Tel: 0519-85528066 13775048983
Fax: 0519-85528066
Email: sales@hopschem.com
Country: China
ProdList: 31553
Advantage: 55

BePharm Ltd

Tel: 400-685-9117
Fax: 021-51816740
Email: market@bepharm.com
Country: China
ProdList: 15081
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

More

Less

View Lastest Price from 1-(4-FLUOROPHENYL)-2-PYRROLIDINONE manufacturers

Career Henan Chemical Co

Product: 1-(4-FLUOROPHENYL)-2-PYRROLIDINONE 54660-08-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98% HPLC
Supply Ability: 10t
Release date: 2019-12-20

54660-08-1, 1-(4-FLUOROPHENYL)-2-PYRROLIDINONERelated Search:

1-(4-FLUOROPHENYL)-2-PYRROLIDINONE 4-(3`-FLUOROPHENYL)-2-PYRROLIDINONE 3-METHOXYCARBONYL-4-(2`-FLUOROPHENYL)-2-PYRROLIDINONE 4-(2`-FLUOROPHENYL)-2-PYRROLIDINONE 3-METHOXYCARBONYL-4-(4`-FLUOROPHENYL)-2-PYRROLIDINONE 4-(4`-FLUOROPHENYL)-2-PYRROLIDINONE 3-METHOXYCARBONYL-4-(3`-FLUOROPHENYL)-2-PYRROLIDINONE N-(4-FLUOROPHENYL)SUCCINIMIDE 1-(4-FLUOROPHENYL)-3-[4-(4-FLUOROPHENYL)PIPERAZIN-1-YL]PYRROLIDINE-2,5-DIONE CHEMBRDG-BB 5311496 3-(4-BENZHYDRYLPIPERAZIN-1-YL)-1-(4-FLUOROPHENYL)PYRROLIDINE-2,5-DIONE 3-(4-BENZYLPIPERAZINO)-1-(2,4-DIFLUOROPHENYL)DIHYDRO-1H-PYRROLE-2,5-DIONE 3,3'-(PIPERAZINE-1,4-DIYL)BIS(1-(4-FLUOROPHENYL)PYRROLIDINE-2,5-DIONE) 1-(2,4-difluorophenyl)-3-morpholinodihydro-1H-pyrrole-2,5-dione 1-(2,4-difluorophenyl)-3-piperidinodihydro-1H-pyrrole-2,5-dione 1-(2,4-DIFLUOROPHENYL)-3-[(4-METHYLPHENYL)SULFANYL]DIHYDRO-1H-PYRROLE-2,5-DIONE 3-[(4-CHLOROPHENYL)SULFANYL]-1-(2,4-DIFLUOROPHENYL)DIHYDRO-1H-PYRROLE-2,5-DIONE 1-(2,4-DIFLUOROPHENYL)DIHYDRO-1H-PYRROLE-2,5-DIONE

BUTTPARK 32\07-63

1-(4-FLUOROPHENYL)-2-PYRROLIDINONE

1-(4-Fluorophenyl)-2-pyrrolidone 97%

1-(4-Fluorophenyl)-2-pyrrolidone97%

1-(4-Fluorophenyl)pyrrolidin-2-one

1-(4-FLUOROPHENYL)-2-PYRROLIDINONE 99+%

1-(4-Fluorophenyl)-2-oxopyrrolidine, 1-Fluoro-4-(2-oxopyrrolidin-1-yl)benzene

1-(4-Fluorophenyl)pyrrolidin-2-one 97%

1-(4-Fluorophenyl)pyrrolidin-2-one 95+%

2-Pyrrolidinone, 1-(4-fluorophenyl)-

54660-08-1

C10H10FNO

Halides

Phenyls & Phenyl-Het