8-BROMO-CADP-RIBOSE

Product Name: 8-BROMO-CADP-RIBOSE
CAS No.: 151898-26-9
Chemical Name: 8-BROMO-CADP-RIBOSE
Synonyms: Br-cADPR;8-BR-CADPR;BR-CADP-RIBOSE;8-BROMO-CADP-RIBOSE;Br-cADP-ribose, Br-cADPR;8-bromo-Cyclic ADP-Ribose;8-Bromo-cADP-Ribose (8-Br-cADPR);8-BROMO-CYCLIC ADENOSINE DIPHOSPHATE RIBOSE;8-Bromo-cADP-Ribose (8-Br-cADPR) DISCONTINUED;8-Bromocyclic adenosine diphosphate ribose sodium
CBNumber: CB6357407
Molecular Formula: C15H20BrN5O13P2
Formula Weight: 620.2
MOL File: 151898-26-9.mol

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8-BROMO-CADP-RIBOSE Property

Boiling point:: 941.8±75.0 °C(Predicted)
Density: 2.78±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: H₂O: 5 mg/mL
form: lyophilized powder
pka: 0.97±0.70(Predicted)
color: white
Water Solubility: H2O: 5mg/mL
InChIKey: PLQQKRPSINJWTK-VNMBDIRDSA-N
SMILES: Nc1ncnc2n([C@@H]3O[C@@H]4COP(O)(=O)OP(=O)(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H]5O)O[C@H]4[C@H]3O)c(Br)nc12

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 29349990
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 18442
Product name: 8-bromo-Cyclic ADP-Ribose
Purity: ≥95%
Packaging: 1mg
Price: $369
Updated: 2021/12/16

Usbiological

Product number: 295421
Product name: 8-Bromocyclic adenosine diphosphate ribose sodium salt
Packaging: 300ug
Price: $576
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: NUC0002063
Product name: 8-BROMO-CYCLIC ADENOSINE DIPHOSPHATE RIBOSE
Purity: 95.00%
Packaging: 0.5MG
Price: $701.09
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NB05042
Product name: 8-Bromocyclic adenosine diphosphate ribose sodium salt
Packaging: 900ug
Price: $378
Updated: 2021/12/16

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8-BROMO-CADP-RIBOSE Chemical Properties,Usage,Production

Chemical Properties

white lyophilized powder

Uses

8-Br-cADPR is a potent cADPR antagonist. 8-Br-cADPR reduces renal damage and the expression of caspase-3 and TRPM2[1].

Biochem/physiol Actions

An antagonist of cyclic ADP-ribose (cADPR), and an endogenous metabolite of β-NAD+. cADPR has been shown to regulate calcium release from the endoplasmic and sarcoplasmic reticulum. In cells, cADPR is synthesized by ADP-ribosyl cyclase or CD38, a lymphocyte differentiation antigen.

References

[1] Eraslan E, et al. 8-Br-cADPR, a TRPM2 ion channel antagonist, inhibits renal ischemia-reperfusion injury. J Cell Physiol. 2019 Apr;234(4):4572-4581. DOI:10.1002/jcp.27236

8-BROMO-CADP-RIBOSE Preparation Products And Raw materials

Raw materials

Preparation Products

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8-BROMO-CADP-RIBOSE Suppliers

China 36 Germany 1 India 1 Switzerland 2 United Kingdom 2 United States 5 Global 47

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
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Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
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Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
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NewCan Biotech Limited

Tel: +86-0571-86912261 +8613735419629
Email: sales@newcanbio.com
Country: China
ProdList: 9985
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Energy Chemical

Tel: 021-58432009 400-005-6266
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MedBioPharmaceutical Technology Inc

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Email: order@med-bio.cn
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Shanghai Universal Biotech Co.,Ltd

Tel: 15921930842 15921930842
Email: yh-wang@univ-bio.com
Country: China
ProdList: 25004
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Shanghai Yingxin laboratory equipment Co., Ltd

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Country: China
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Shanghai Guchen Biotechnology Co., LTD

Tel: 021-34675735 19147740836
Email: 1986399151@qq.com
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151898-26-9, 8-BROMO-CADP-RIBOSERelated Search:

Clindamycin phosphate CADP-RIBOSE 8-BROMOADENOSINE 5'-MONOPHOSPHATE 8-BROMOADENOSINE 8-BROMO-CADP-RIBOSE 8-BROMO-2'-DEOXYADENOSINE 6-Amino-2-bromopurine

8-BR-CADPR

8-BROMO-CYCLIC ADENOSINE DIPHOSPHATE RIBOSE

8-BROMO-CADP-RIBOSE

BR-CADP-RIBOSE

Br-cADP-ribose, Br-cADPR

8-Bromocyclic adenosine diphosphate ribose sodium salt

Br-cADPR

8-Bromo-cADP-Ribose (8-Br-cADPR)

8-bromo-Cyclic ADP-Ribose

Adenosine 5'-(trihydrogen diphosphate), 8-bromo-1-β-D-ribofuranosyl-, intramol. P',5''-ester

8-Bromo-cADP-Ribose (8-Br-cADPR) DISCONTINUED

8-Bromocyclic adenosine diphosphate ribose sodium

151898-26-9

C15H20BrN5NaO13P2

C15H19BrN5NaO13P2

C15H20BrN5O13P2

Intracellular Calcium Regulators

Intracellular Calcium Signaling

Cell Signaling and Neuroscience

Cell Biology

BioChemical