(TETRAHYDROFURAN-3-YL)METHANAMINE HYDROCHLORIDE
- Product Name
- (TETRAHYDROFURAN-3-YL)METHANAMINE HYDROCHLORIDE
- CAS No.
- 184950-35-4
- Chemical Name
- (TETRAHYDROFURAN-3-YL)METHANAMINE HYDROCHLORIDE
- Synonyms
- 3-oxolanylmethanamine;1-Tetrahydrofuran-3-ylmet...;oxolan-3-ylmethanamine hydrochloride;(Tetrahydrofuran-3-yl)MethanaMine HCl;Tetrahydro-3-furanmethanamine hydrochloride;3-Tetrahydrofuranylmethylamine hydrochloride;3- Tetrahydro-furanmethanamine hydrochloride;3-(Aminomethyl)tetrahydrofuran hydrochloride;(3-Tetrahydrofuranyl)methanamine hydrochloride;(TETRAHYDROFURAN-3-YL)METHANAMINE HYDROCHLORIDE
- CBNumber
- CB6362041
- Molecular Formula
- C5H12ClNO
- Formula Weight
- 137.61
- MOL File
- 184950-35-4.mol
(TETRAHYDROFURAN-3-YL)METHANAMINE HYDROCHLORIDE Property
- Melting point:
- 72-92 °C
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- 722715
- Product name
- 3-(Aminomethyl)tetrahydrofuran hydrochloride
- Purity
- 95%
- Packaging
- 250mg
- Price
- $73.8
- Updated
- 2023/01/07
- Product number
- T795463
- Product name
- (Tetrahydrofuran-3-yl)methanamineHydrochloride
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- W3996
- Product name
- (Tetrahydrofuran-3-yl)methanaminehydrochloride
- Packaging
- 1g
- Price
- $72
- Updated
- 2021/12/16
- Product number
- 4H56-5-60
- Product name
- Oxolan-3-ylmethanamine hydrochloride
- Packaging
- 25g
- Price
- $500
- Updated
- 2021/12/16
- Product number
- CHM0078030
- Product name
- (TETRAHYDROFURAN-3-YL)METHANAMINE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $939.87
- Updated
- 2021/12/16
(TETRAHYDROFURAN-3-YL)METHANAMINE HYDROCHLORIDE Chemical Properties,Usage,Production
Synthesis
79710-86-4
24424-99-5
184950-35-4
A. Synthesis of (tetrahydrofuran-3-yl)methylamine hydrochloride. A mixture of tetrahydrofuran-3-carbaldehyde (50 wt%, aqueous solution, 5 mL, 25 mmol), ammonium chloride (13 g, 25 mmol), and Ruanne nickel (2 mL slurry) in methanol was placed in a Parr shaker and reacted at 40 °C. Hydrogen was passed through and kept at room temperature for 16 hours. After completion of the reaction, the mixture was filtered through diatomaceous earth and the filtrate was concentrated to obtain an oily substance. To this oily substance was added dioxane (50 mL), 1 M sodium hydroxide solution (50 mL) and di-tert-butyl dicarbonate (5.5 g, 25 mmol). The reaction mixture was stirred at room temperature for 16 hours. After completion of the reaction, extraction was carried out with ethyl acetate and water. The organic layer was dried with magnesium sulfate, filtered and concentrated to give an oil. The oil was purified by silica gel column chromatography (eluent: 0-20% ethyl acetate in hexane solution) to give a clarified oily product. The oily product was treated with a dioxane solution of 4 N HCl. The reaction solution was concentrated and ground with ether to give a white solid product (0.33 g, 10% yield). MS (ESI) m/z 101.9 [M + 1]+.
References
[1] Patent: WO2008/51493, 2008, A2. Location in patent: Page/Page column 173
(TETRAHYDROFURAN-3-YL)METHANAMINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (TETRAHYDROFURAN-3-YL)METHANAMINE HYDROCHLORIDE manufacturers
- Product
- (TETRAHYDROFURAN-3-YL)METHANAMINE HYDROCHLORIDE 184950-35-4
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-13