3-BROMO-5-METHYLBENZONITRILE
- Product Name
- 3-BROMO-5-METHYLBENZONITRILE
- CAS No.
- 124289-21-0
- Chemical Name
- 3-BROMO-5-METHYLBENZONITRILE
- Synonyms
- Bromo-5-methyl-benzonitrile;3-BROMO-5-METHYLBENZONITRILE;3-Methyl-5-bromobenzonitrile;Benzonitrile,3-bromo-5-methyl-;3-BroMo-5-Methylbenzonitrile, 95+%
- CBNumber
- CB6367990
- Molecular Formula
- C8H6BrN
- Formula Weight
- 196.04
- MOL File
- 124289-21-0.mol
3-BROMO-5-METHYLBENZONITRILE Property
- Melting point:
- 57-58.5℃
- Boiling point:
- 256.1±20.0℃ (760 Torr)
- Density
- 1.51±0.1 g/cm3 (20 ºC 760 Torr)
- Flash point:
- 108.7±21.8℃
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- solid
- color
- White to off-white
Safety
- HS Code
- 2926907090
N-Bromosuccinimide Price
- Product number
- B688145
- Product name
- 3-Bromo-5-methylbenzonitrile
- Packaging
- 1g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- B688145
- Product name
- 3-Bromo-5-methylbenzonitrile
- Packaging
- 5G
- Price
- $155
- Updated
- 2021/12/16
- Product number
- FB139552
- Product name
- 3-Bromo-5-methylbenzonitrile
- Packaging
- 5G
- Price
- $170
- Updated
- 2021/12/16
- Product number
- 074002
- Product name
- 3-Bromo-5-methylbenzonitrile
- Purity
- 95+%
- Packaging
- 1g
- Price
- $46
- Updated
- 2021/12/16
- Product number
- J90931
- Product name
- 3-Bromo-5-methylbenzonitrile
- Packaging
- 1g
- Price
- $47
- Updated
- 2021/12/16
3-BROMO-5-METHYLBENZONITRILE Chemical Properties,Usage,Production
Uses
3-Bromo-5-methylbenzonitrile is used in the synthesis of arenes with high steric regiocontrol.
Synthesis
1007578-82-6
124289-21-0
Example 45 Synthesis of 3-bromo-5-methylbenzonitrile: Phosphorus pentoxide (29.8 g, 210.2 mmol) was added to a chloroform suspension of 3-bromo-5-methylbenzamide (15.0 g, 70.1 mmol), and the reaction mixture was stirred under reflux conditions for 2 days (the reaction progress was monitored by thin layer chromatography). Upon completion of the reaction, the mixture was cooled to room temperature and slowly poured into ice water with stirring. The organic layer was separated and the aqueous layer was extracted with dichloromethane (150 mL x 2). The organic phases were combined, washed with saturated saline and dried over anhydrous sodium sulfate. Purification by fast column chromatography afforded the target product 3-bromo-5-methylbenzonitrile (7.20 g, 52% yield).1H NMR (400 MHz, CDCl3) δ 7.60-7.56 (m, 2H), 7.40-7.39 (m, 1H), 2.39 (s, 3H).
References
[1] Patent: US2009/203657, 2009, A1. Location in patent: Page/Page column 53
[2] Patent: US2009/203677, 2009, A1. Location in patent: Page/Page column 56; 57
[3] Patent: US2009/197871, 2009, A1. Location in patent: Page/Page column 56
[4] Patent: WO2009/100169, 2009, A1. Location in patent: Page/Page column 137
3-BROMO-5-METHYLBENZONITRILE Preparation Products And Raw materials
Raw materials
Preparation Products
3-BROMO-5-METHYLBENZONITRILE Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
View Lastest Price from 3-BROMO-5-METHYLBENZONITRILE manufacturers
- Product
- 3-Bromo-5-methylbenzonitrile 124289-21-0
- Price
- US $42.00-585.00/g
- Min. Order
- 5g
- Purity
- 0.98
- Supply Ability
- 10kg
- Release date
- 2023-12-20
- Product
- 3-BROMO-5-METHYLBENZONITRILE 124289-21-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-11