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Chlorophacinone

Product Name
Chlorophacinone
CAS No.
3691-35-8
Chemical Name
Chlorophacinone
Synonyms
YY1;lm91;CAID;DRAT;Afnor;delta;LM 91;Quick;Ranac;Rozol
CBNumber
CB6372862
Molecular Formula
C23H15ClO3
Formula Weight
374.82
MOL File
3691-35-8.mol
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Chlorophacinone Property

Melting point:
138°
Boiling point:
490.38°C (rough estimate)
Density 
1.1517 (rough estimate)
refractive index 
1.4585 (estimate)
Flash point:
>100 °C
storage temp. 
-20°C
pka
2.61±0.10(Predicted)
Merck 
13,2171
NIST Chemistry Reference
Chlorophacinone(3691-35-8)
EPA Substance Registry System
Chlorophacinone (3691-35-8)
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Safety

Hazard Codes 
T+;N,N,T+
Risk Statements 
23-27/28-48/24/25-50/53
Safety Statements 
36/37-45-60-61
RIDADR 
UN 2811
RTECS 
NK5335000
HazardClass 
6.1(a)
PackingGroup 
I
HS Code 
29147000
Hazardous Substances Data
3691-35-8(Hazardous Substances Data)
Toxicity
LD50 oral in rabbit: 50mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

H310Fatal in contact with skin

H331Toxic if inhaled

H372Causes damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P350IF ON SKIN: Gently wash with plenty of soap and water.

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Chlorophacinone Chemical Properties,Usage,Production

Description

Chlorophacinone is produced by condensation of 1- phenyl-1-(4-chlorophenyl) acetone with dimethyl phthalate in the presence of sodium methoxide (31).
This compound was introduced in 1961 and is now widely used in Europe, the United States, and elsewhere. It is used in baits against norway rats at a concentration of 0.005–0.01%. Bait containing 0.025% chlorophacinone gave a complete kill of house mice after a 7-d feeding period but, in other tests, survivors were recorded following 10 and 21 days of feeding (5). Chlorophacinone acts as an uncoupler of oxidative phosphorylation as well as an anticoagulant (32), which is unusual among this group of compounds.

Chemical Properties

Chlorophacinone is a highly toxic crystalline solid.

Uses

Chlorophacinone (CPN) is an anticoagulant rodenticide widely used to control rodent infestations.

Uses

Anticoagulant rodenticide.

General Description

Crystals. Commercially available as oil concentrate and as dust concentrate. Used as an anticoagulant rodenticide. Chronic acting, multiple dose rodenticide.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Fire may produce irritating or poisonous gases.

Health Hazard

Chlorphacinon is highly toxic orally and by skin absorption. The probable oral lethal dose for humans is less than 5 mg/kg to 50 mg/kg, or between a taste (less than 7 drops) and 1 teaspoonful for a 150 lb. (70 kg) person.

Health Hazard

Highly toxic anticoagulant rodenticide; lowchlorine content but highly toxic; exhibitsacute, delayed, and chronic poisoning;symptoms include bleeding of nose andgum, blood in cough, urine, and stool,abdominal pain and hemorrhage; can beabsorbed through skin causing systemicpoisoning; ingestion of 1–2 g is estimatedto be fatal dose for adult human; U.S. EPAlisted extremely hazardous substance.
LD50 oral (rat): ~2 mg/kg
LD50 oral (mouse): ~1 mg/kg
LD50 oral (rabbit): 50 mg/kg
LD50 skin (rabbit): 200 mg/kg.

Fire Hazard

(Non-Specific -- Coumarin Derivative Pesticide, Solid, n.o.s.) Fire may produce irriating or poisonous gases. Runoff from fire control water may give off poisonous gases. Runoff from fire control or dilution water may cause pollution. When heated Chlorphacinon emits toxic fumes of chlorides.

Agricultural Uses

Rodenticide: This material is an anticoagulant rodenticide used around livestock and also on crops such as artichokes. Some brands are labeled for use indoors and outdoors for the control of mice, rats, moles, muskrats, voles and vampire bats. Not approved for use in EU countries. Registered for use in the U.S. There are 24 global suppliers.

Trade name

AFNOR®; CAID®; DELTA®; DRAT RAT BAIT®; ENDORATS®; LIPHADIONE®; LM 91®; MICROZUL®; MURIOL®; PARTOX®[C]; QUICK®; RAMUCIDE®; RANAC®; RATOMET®; RAVIAC®; ROZOL®[C]; TOPITOX®

Safety Profile

Poison by ingestion and skin contact. Human systemic effects by ingestion: vascular changes. A pesticide. When heated to decomposition it emits toxic fumes of Cl-.

Potential Exposure

Agricultural Chemical. This material is an anticoagulant rodenticide. A potential danger to those involved in its manufacture, formulation, and application are at risk.

Shipping

UN3027 Coumarin derivative pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Waste Disposal

Incineration at high temperature with effluent gas scrubbing.

Chlorophacinone Preparation Products And Raw materials

Raw materials

Preparation Products

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Chlorophacinone Suppliers

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